LOCUS       gnlProkkaICJHBCCI_5    12938 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ICJHBCCI_5.
ACCESSION   gnlProkkaICJHBCCI_5
VERSION     gnlProkkaICJHBCCI_5
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-05-22 09:40:21
            Original ID  :: gnl|Prokka|ICJHBCCI_5
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12938
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12938
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3246:3952]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3247..3952
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..12938
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12938
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             141..374
                     /locus_tag="ctg4_1"
                     /transl_table=11
                     /translation="MSVENNYCKLQQAHDQKCRVSLRFYKTNGQMAETVGYVTTIVPKA
                     IAFMAITGHRHLIQLNRIITVSLQSQDRRYVM"
     CDS             765..2879
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     960.6; E-value: 1.2e-290)"
                     /gene_kind="other"
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP
                     DEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREN
                     EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS
                     LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH
                     HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK
                     LEAAKEAAVKSEDFKKAADIKKSIEETKQKIKKTDQKEKIIATIDDVAQSVERLTGIPV
                     ADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT
                     GVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER
                     VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGN
                     EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA
                     KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL
                     VDAEIVISAA"
     CDS             3247..3843
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="AgrB (E-value: 2.1e-35, bitscore: 111.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV
                     IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV
                     IGTGISEVYRLLLSLIFVIIISIFAPADTVKNPITSKSLRKKLKRRAIGLSLILSLLQI
                     VSNNYFGTIILIAMALAALLLMPYERRENYERKNV"
     CDS             3824..3952
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="TIGR04223 (E-value: 9.4e-09, bitscore:
                     25.3, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKMYKVLSHLFQYVGTKQLVMCCHGILFETKIPDELKSKD"
     CDS             3962..5224
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA
                     KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY
                     VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ
                     VILSNLIILSVVMGLVLVIYNEYLKNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR
                     FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS
                     ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS
                     AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE
                     TRVLGAVFLQRLTVKRVSQND"
     CDS             5217..5960
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDMSICLACQDPHELL
                     DKVNAQQPQKAIYVLDIALNSDINGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV
                     EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF
                     ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYRCHKSYVVNLKRIKSLDKHLRRLT
                     MTNGEKVLCSAQANRYLAKWLAKKS"
     CDS             6316..6753
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MIRLYTQSSCHSSRVARQWLEAHGIEFKEKNFSVDSPTVQDLKRI
                     LSLTEHGVDDIISARSKDYPEIAPKLPEMPLNEALKLLCDHPKLLRRPIIISDSKIQVG
                     FNEDDIRQFIPRPVRRLKFNALLSRLDGNTGDHIINKRMVE"
     CDS             complement(6911..8362)
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MTEKLTTETGQPWANNEHSQTAGARGPVLMQDYNLLEKLAHFDRE
                     RIPERVVHAKGAGAKGFFELENDMGEYTKADLFNGVGKKTPVILRFSQVAGEKGYPDTV
                     RDVRGFALKFYTQQGNYDLVGNNTPVFFVNDPLKFPDFIHSQKRDPKTNRRTQNMQWDF
                     WAHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVNQNGEQFWVKYHFISDQGVKN
                     MTAQAAEKAMSQDLDYLQDDLYDAIQEKNYPSWTMYVQILPYEEGLNYKWDIFDVTKVI
                     SHKDYPLIKVGKLTLNENPTNNFTDIEEAAMSPANFVPGIEPSPDKLLQGRLFSYKDAQ
                     RYRLGANFEDLPVNKPVVPVHNYERDGYMKINNQGAEVNYEPNALHGPEEVPDAALSPD
                     SVRGETRAQPYRYQVDYTTQAGDLYLMSEPEQERLINTIKDALGQVTLPGVKKLEIKQF
                     YEADKNYGTRVANALGMNIADIISD"
     CDS             8708..8953
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MHWLWVLIIGAIIGAIAGAITNKGKSMGWISNIIAGLVGSAIGEA
                     LLGSWGPQLAGMAIVPSIIGGVIVVAITSFVLTRMD"
     CDS             8970..9104
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MIKSILKFCLAATLIVSGVLIGGTVLTAKGIDNLGDKLQDKLHG"
     CDS             9299..9847
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MSKLIAKNVFQLPKMNLLVLTTSAFLLALDVILYKIAIGPAYFQL
                     SFGFLSMACIGYLYGPIWGGLLEMISDILSFTIFGSGAFQIAFLLTAFLGGFIDGLFLY
                     RKSVNWLSVVMTQILVMIFVSLMMDSWLISVLFGTNFKVLLLGRLARVIIQIPLQVIAI
                     FYFIKALEKRHVFDRMRLR"
     CDS             complement(10043..10414)
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MRLWHEQLIHQLPRQQLLGQHRELAALKGNGWGKNHATVNYVFKY
                     SPYKLYQFHVLVMDEMQLRGYHPNKIWYDPNYRGQFCPPYDHLTPIALTTPIYPEHNAS
                     YLAECVRNLAAKGIIMPTT"
     CDS             10881..12086
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 125.7; E-value: 3e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_13"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.2e-54, bitscore:
                     175.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLDQTNNYRYVIVGGGMVAGYAIKGIRQEDPEGAILVISQEAD
                     VPYERPALSKKLWLDDEFTEENIRIGAEDYPNVTFKFKTTVTAINRQDKVITLTDSEQI
                     KYEQLLLATGGEPRQIQGPADPHVLVFRQWSDYRKLRKFSGPNKRVVIIGGGYVGTELA
                     SSLTQNGTKVTMIFPEKALGEGKFPESIRAEYEATFKRNGVTLMSGQFVQSYQRQGDHL
                     TLLTKDGTAIAADTIIVGLGVTPRISLAEDSSLDLADGGVKVDEYLNTSDPAIWSAGDI
                     ASYPDHILGRQRIEHVDHARLSGELVGRNMAGAHMSYQHTPYFYSMIFDISWQAIGNID
                     PKLQLIFDRRTHGSLVYFIDAGKLVGVLVWNVKVNLDDVRALLANAPATDDLVGSIREQ
                     EG"
     CDS             complement(12225..12911)
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="MKNTFLNTVKGSLIISCQALPNEPLHSSFIMSRMALAAKEAGAAG
                     IRANSVVDIQAIQDEVDLPLIGLSKVDYPDSPVYITPTIKEMRAVAATGCAVVACDVTG
                     QPRPNGEKLAEIVATMRTEFPDTLLMADTDTIENVKVADRLGFDIIGTTMHGYTPATTG
                     ANIADNDFAYLKEVLQATSRPVIAEGKVDTPEKMKRCLDLGCHAVVVGAAITRPLEIAQ
                     RFISAL"
ORIGIN
        1 aacatgaata ctagttattt agtttttact gaatagctga ctccttaatg tggacttacg
       61 ccgtcaacaa tgagaaaaac aaacacatag attcactgac gaataaataa acctgaattc
      121 tttgaacggg agactttaat ttgagtgttg aaaataatta ttgtaaatta caacaagcgc
      181 atgatcaaaa atgtcgagtc tcattacggt tttataaaac aaatgggcag atggccgaga
      241 cagttggcta tgtcactacg attgtaccga aagcaattgc atttatggca attactggtc
      301 atcggcacct tatccaactc aatagaatca ttactgtgag tttacagtcc caagaccgcc
      361 gttacgtcat gtaatatgtt ttggtttatg attttacacg tgtatcatga ttgctagtat
      421 tgatatttaa gtggcaatat taacgataac tagttggcct taacttgata ctgggtgtgc
      481 tttttgagtc gcagtctctt aaattaaaat tggtctggaa agtaacttgt taattcaagt
      541 tctttatcaa gggctattaa atagggaacc ttgtagggaa atcaattcat tttatgaaat
      601 tgatttctct tttgtttaaa caaaattatt ctaattattt ctaattgatt ctataagcac
      661 tttacttaac gatacataaa aatcgtgata cgattcagtt gtagttttaa aggatattat
      721 ggtcactaag ttacacatat aaatttttat ggaggtgttg taatatggca aatttctacg
      781 gaaatgatcc ttttttcaac aatgatatgg atgatgtttt caatcaatta tttcggcgca
      841 tggataatca aaattcggag cgtgcacggt atttagttaa tggacaatcg ctgacaccgg
      901 atgagtttgc tcaataccga gcaactggta agctacccca aaataataaa acaatagaag
      961 tatctaaaga tggtaaacag gctgttaaaa aaggggggat tttagaaaag ttagggacta
     1021 atttgacgga acaggctcgt gatggattac tagatccagt gattggacgt gagaatgaga
     1081 ttcaagaaac tgcagaaatt ttgagtcgta ggacgaaaaa taatccaatc ttagttggtg
     1141 atgctggtgt aggtaaaact gcagtcgtcg aaggtctggc acaagcaatt gtggctggta
     1201 aagttccaga aacgattcaa gataaagaaa tctattcgat tgatttatcg tctttggaag
     1261 caggaactca atatcgcggt tcttttgaag agaatattaa acagctggta aaggaagtta
     1321 aagcagctgg taatattatt ctattcttcg atgaaattca tcagattatc ggcacgggtg
     1381 ccactggtgg tgaagacggt ggcaagggat tggctgatat cattaaacct gctttgtcac
     1441 gtggcgagct gactgtaatc ggggctacga ctcaagatga atatcgcaat actattttga
     1501 aaaatgcggc tttggcacgg cgattcaatg atgttgtgat taatgaaccg acggccgctg
     1561 acactttacg tatattacaa ggtgttaaaa agctgtacga aaagcatcat catgttgtat
     1621 taccagatga tgttttgaag gcggctgtgg attattcaat ccaatatata ccacaacgca
     1681 ctttgccaga taaagctatc gatttgatcg acatgactgc ggctcattta gcggctaaaa
     1741 attcgcaaac tgatgttgag acattggatc aacgcgttaa aaaattagag gcagctaagg
     1801 aggccgccgt taaatcggag gactttaaaa aagccgctga tatcaagaag tcgatcgagg
     1861 aaaccaagca aaaaattaaa aaaacggatc aaaaagaaaa aatcattgcc acgattgatg
     1921 atgtggcaca atcggttgaa cgtttaactg gtataccagt tgctgatatg ggcgctaatg
     1981 atattgagca cttgaaaaat cttgataagc gtctgaaaag taaggtaatc ggtcaagatg
     2041 aagcggttga aatggtagcg aaggcaattc ggcgtaaccg tgcgggcttt tcagagggtg
     2101 atcagccaat tggaagtttt ctgtttgtgg gcccaactgg cgtaggaaag actgaattag
     2161 ctaagcaatt agccttagat atgtttggaa ataaaaatgc gattattcgg ctagatatga
     2221 gtgaatatgc tgatcgtaca gctgtgtcga aattaattgg tacctcggct ggatacgtag
     2281 gctatgaaga taatgctaat actctaaccg aacgggttcg gcgtaatcca tattccattg
     2341 tattattaga tgaaattgaa aaggctgatc cacaagtatt aacgttactg ttacaagtga
     2401 tggatgatgg gcgcttaacg gatggacaag gcaatgtcat taatttcaaa aatacgatta
     2461 ttatcgctac ttctaatgct ggctttggta atgaagcatt aagtggtgac aagcaacgag
     2521 atcagtcatt aatggataag ttagcaccat ttttccgccc agaatttctg aaccgtttta
     2581 atggaatcgt ggaattttca catctgacta agcaagactt aagtcaaatt gtcgatttga
     2641 tgttggcgga tgtacaaaaa acgttagcca aaaaatccat caaacttgag gtaactaaag
     2701 cggccaaaga ttggctgatg gaacaaggct atgatgaagc gatgggtgcg cggccattac
     2761 ggcgagtaat tgaacaacaa attcgtgaca aggtaacgga tttctacctt gaccacttag
     2821 atgtcaaaaa cttgaaggct gatttagtgg atgctgagat tgtgatatcg gcagcttagc
     2881 ttaaatcagt gttcataaat aactttatgt aagaggagat tgcttgatag atctcctctt
     2941 ttcgttgatt ttcaccattt gatattaatc tattgagtaa tgtgaattag tgaaattaag
     3001 tctagtttga cttgtaatct aaggaaaaat taagggggag tatcgatgaa actgatttat
     3061 attaacgatc tttttacatg aaactttagt ttcgtatgaa taattaaact gatgtatctt
     3121 taaatgttta tttctagtct taaaacaata ttgaataatt aatatattta tgtattcttt
     3181 tcaattaatt aatactgttt taaactgttg atacaggtat gtatttgagc attataggag
     3241 tgggatatgg aaaagccaga acaaaaacta ttgctttata aattaagcga tcggttattc
     3301 gctgcgattc aaaagaatct tcaactagaa agacggcagg cattactagt taaactaggc
     3361 attgatactg tattaaatgt tattcctaag ctgataatta ctattatctt agcgttgctg
     3421 ctacacgagt tggtcccagt gttagttttt atgggtagtt ttttagtttt gcgtggcttt
     3481 gcctatggac gtcacttgaa atcggatttg ttatgtacga tattaactat ctttgtgttt
     3541 gtgggtgtgc cgtatgtgat tggaactggt atttctgaag tatacagatt gttattaagt
     3601 ttaatatttg taataatcat aagtattttt gctccagctg atacggtaaa gaatcctatt
     3661 acatcgaagt cattgagaaa aaaattaaag cgacgggcaa ttggattgtc attaattttg
     3721 agtttgttac aaatagttag taataattat tttggcacaa tcattttaat tgcgatggca
     3781 ttagccgctt tattactaat gccctatgaa aggagggaaa attatgaaag aaaaaatgta
     3841 taaagtactt agccatcttt ttcaatacgt aggtactaaa cagttggtta tgtgctgcca
     3901 tgggatatta ttcgaaacta aaattcctga tgaattaaaa agcaaggatt agtgtagata
     3961 tatgttaatg attgtcttcc aagaattatc tatctatttg ataattaaat ctttgttgag
     4021 aaatatattt tttgtgagac tttttgatgt tatattctta tccgtctgta tgctgatgag
     4081 ttatattttt ttagcaaagt taggaattag tttttctttt ttaatgttaa tgatgtttat
     4141 atttttcact tggtggtatg tacgagttct aagcggtgca ctatgtataa catttcaagt
     4201 gttcatatgg tcgattatgg ttgaccatat ttgtgatata ttaactcgtt taatgaaagt
     4261 tcctaatggg tatgtggtag tgtttgtcat attgagtgtc gtaagcttaa tttttcttaa
     4321 tattgtaatg gatcgcacga atttcagtcc cacgtttagt aatcagagct taaatcgcat
     4381 aaccgcacta ttattaatga taatatactt gtatattatg ttgagtgaag gtctggaaaa
     4441 tcagttccag gttatattaa gtaatttaat tatattgtca gttgtaatgg ggttagtatt
     4501 ggtgatttat aacgaatatt taaaaaatgt aagagccaaa tatgaagtcc aaaagcaaag
     4561 aatacaaata caaaatgata ctcgctatat gaatgaaatc gaagctcact ataatgagtt
     4621 gcgacgtttc agacatgact atcagaatat gttgatttcg atagatgaat atttgaaaac
     4681 tgatgattta gaaggtttac aagaatatta tcaaaagaat cttgcaccgg tttcaaatcg
     4741 ggtgttaaaa gaaaaatata atcttgaaga tttgagtcgg gtcaaagtga agtcgattaa
     4801 gagtatccta tttagtaagt tgagctatgc acaatcgcaa gagattgaag ttcattttga
     4861 tttaaaggaa ccattaattg acattactgt taatgaattg gatttagaca ttgcattagg
     4921 gattatgttg gataatgcaa tcgaagcatc ggtaggacat gctgatggag agattatgag
     4981 tgccattttt atcgaaaaaa atagtacggt gttcttgatt caaaacaatg tttttgaaca
     5041 gttaccaccc ttatggaagc tgaaagaggc aggttattcc actaagggca agaatcgggg
     5101 gattggattg aatagtttaa gtaagattgt taatcgcaat gagaacatga tactcgaaac
     5161 cagagtctta ggagcggtat tcttacaacg cttgacggtg aagcgagtat ctcagaatga
     5221 ttagtgtcta catttgcgaa gatgatccga aacaattaca acaaatacgg caaatcatta
     5281 ctaaggtaat cgtcgatcaa cagctagaca tgagtatctg tttagcatgc caagatcccc
     5341 acgaattgtt agacaaggtt aatgcacagc agcctcaaaa ggcaatctat gtgttagata
     5401 ttgcccttaa ttcagatatt aatggtattc aactagctag ccagattcgt gacatgggcc
     5461 gtcgcagcaa gattattttt atcacgacac acacggagtt atctttgatg gtgtttcaat
     5521 atcaagttga ggcattagat tttattctta aggattttcc agattccttg tatgagcgat
     5581 ttagcaaggt tttacacgtg gcgcaagatc gttttcaaac cgatgaaaat gaccaagacg
     5641 actatgttca aataaaaatt ggtgagacgg tcagatcaat taatgttaaa agcattatat
     5701 tttttgaaag ttcaaccagt ccccataaaa tcgtagtcca tttggatgat ggtgaattag
     5761 aatactatgg actgttaaag gacgttcctg atttgagtcc taatttctat aggtgtcata
     5821 agtcatatgt tgttaacttg aaacgcatta agtcattgga caagcacttg cgacgattaa
     5881 ccatgacaaa tggtgaaaaa gtgctttgtt ctgcacaagc taatcgttat ctagctaaat
     5941 ggcttgctaa aaagtcataa tagttccaag gaagtcgcct gctaaattag taggcgactt
     6001 tttatgtgct acgcgatgaa aattcagcgt tattcgatta gaaattgcag tgatatttgt
     6061 tagcattacg tgtactgggt tcgttctttc ctaaaccgtt taaaagtgta cttaaaacga
     6121 ttatcctcag attattcgtc ttaaaacggt cggtatgtcc cttgttcaga gcctataata
     6181 aagatgtgtt cacggggtat tggattggtc atgacagtaa cgaatgcgtt tagtttaaag
     6241 gatgttgtga caggcagaag ttaatgtcga tcaatacgct gtgatgaatt ttaacgagag
     6301 aggggcagat taggaatgat taggttatat acacaatcaa gctgtcattc ttctagagtt
     6361 gcacggcaat ggttggaagc acatgggatt gagttcaagg agaaaaattt tagtgttgat
     6421 tcgcccacgg tgcaagatct aaaacgtatt ttgagtttaa ccgaacatgg tgtagacgat
     6481 attatctcag ctcgatctaa agactatcct gaaattgcgc ctaagttacc cgaaatgcca
     6541 ttgaatgagg cacttaaatt gttgtgtgat catccgaagt tgttacgtcg gcctatcatc
     6601 attagtgata gtaaaattca agttggcttt aatgaagatg atattcgcca atttattcca
     6661 cgaccagttc ggcgactaaa gttcaatgca ttgttgagtc gtctagatgg taatacaggg
     6721 gatcacatta ttaataaaag gatggtcgag tagtaagcta tatctaagat tttttgttaa
     6781 ttaaagagcg acaagctaga cttacacgat atgagtctaa cctgtcgctc tttagttaat
     6841 aaccatgaga cggcatcatc attctttaca acaaaaataa tatcgcgctg gataacatcc
     6901 ggtcaaaata ttaatcactg ataatatcag caatattcat tcccagagca ttagccacgc
     6961 gtgtaccgta gtttttgtcg gcctcataaa attgcttgat ttcgagtttt ttgacaccag
     7021 gcaaagtaac ttggcctaac gcatctttga tagtattaat taagcgttct tgctcgggtt
     7081 ctgacattag atataggtcg cctgcttgag ttgtgtaatc aacttgatag cgataaggct
     7141 gtgcgcgtgt ttcaccacga acagaatcag gtgaaagtgc ggcatccggc acctcttctg
     7201 gcccatgcag tgcattaggc tcgtagttga cctcagcacc ttgattatta attttcatgt
     7261 aaccatcacg ttcataatta tgaactggaa caaccggctt gttcacgggt aaatcttcaa
     7321 agttggcacc taaccgatat cgctgtgcat ctttatagga gaataggcga ccttgtagta
     7381 atttgtcggg agatggttcg ataccaggaa caaaatttgc tggcgacatg gccgcctctt
     7441 caatatcggt aaagttatta gtgggattct catttaaagt tagtttgccg actttaatta
     7501 gtggatagtc tttgtgggag atgactttag tgacatcaaa aatgtcccat ttatagttta
     7561 gaccttcctc atatggcaag atttggacat acatcgtcca tgatgggtaa tttttttctt
     7621 gaattgcatc atataagtca tcttgtaagt aatctaaatc ttggctcatt gctttttcag
     7681 ctgcttgagc agtcatattt ttaacgcctt ggtctgagat gaagtgatac ttaacccaaa
     7741 actgttcgcc attctgatta acccatttaa aagtatggga accgtaacca ttcatggttc
     7801 gataggacgc aggaagacct cggtcgccca ttaaataagt gacctggtgc aatgattctg
     7861 gagaatgagc ccaaaaatcc cattgcatat tttgcgtacg acggttcgtt ttaggatccc
     7921 gtttttgtga atggatgaag tcaggaaatt ttaaagggtc gtttacaaaa aagaccggtg
     7981 tgttgtttcc aacgagatca taattgcctt gctgagtata aaattttaag gcaaaaccgc
     8041 gcacgtctcg aacggtgtca ggataacctt tttcaccggc aacttgtgag aaccttaaga
     8101 ttacgggagt tttcttaccg acaccattaa ataagtctgc cttagtatat tcccccatgt
     8161 cgttttcaag ttcaaaaaaa ccttttgctc cggccccctt agcatgaacg acccgttctg
     8221 gaattcgttc acgatcaaaa tgggctagtt tttccaaaag attatagtct tgcattaata
     8281 cgggaccacg agctcctgcc gtttgggaat gttcattgtt agcccatggt tggccggttt
     8341 ccgtcgttaa tttttccgtc attttaatcg cccttttcac gtaaattaca aggaagctct
     8401 tgcacaattt aaacgctaac accttaacag agtgacttca atcattatgc acagttaagt
     8461 taatcgttca tgtggcgtag tttaatttta atcagctatc aagctgtttg atattttcta
     8521 ggccacccgg aatcgtcaca tgagaaatag tagcgaccca tttattaaat aatgtgttat
     8581 atttgtctat cattatcgat aattgtaaaa tgataattat aagaagtaat catttatgaa
     8641 tcggcttaaa tattcgtgta attctattat tgtatttaag cggtttaata agtctaggag
     8701 ggattttatg cattggttat gggttttgat cattggtgct attattggtg caattgcagg
     8761 tgctattact aataaaggta aatcgatggg gtggattagt aatattattg ccggattggt
     8821 tggatctgca attggggaag ctcttttggg atcatgggga ccacaattag ccggaatggc
     8881 aattgttcct tcaattattg gtggtgtgat tgttgttgcg ataacctcat ttgttctgac
     8941 acggatggat tagtaaggag atgattgcga tgattaaaag cattttaaag ttttgtttag
     9001 ctgcaacctt aatcgtaagt ggtgttctta ttggtgggac cgtacttact gctaagggaa
     9061 ttgataactt gggtgataaa ttacaagata agttacatgg ataaaaatta attttacaat
     9121 gagccactga tgggtgtact agttgacctg ttagtggctt ttagtatgag taatatcatt
     9181 gagttcaagg aactaaatca agagcgacga ttttaaacta ccttcaatcg aataaaagta
     9241 atatttactt ttattaagaa tgagggtatg attaaaatca aaaaaagagg attggcctat
     9301 gtctaaactt attgcgaaaa atgtttttca gttgccaaaa atgaatttat tagtgctgac
     9361 tacatcggct ttcttattgg ccttagacgt tattttatac aaaattgcta tcggaccagc
     9421 gtattttcaa ttatcttttg gctttttgtc tatggcttgt attggttatc tatatggtcc
     9481 catttggggt ggtctcttgg agatgatctc cgatatatta agctttacta tttttggttc
     9541 cggcgcgttt cagattgcct ttttgttaac tgcattttta gggggattta ttgacggttt
     9601 gtttttatat cgtaaatcag tcaattggtt atccgttgtg atgacgcaaa tacttgtaat
     9661 gatttttgtt agtttgatga tggactcatg gctaatttca gtgctatttg gcactaattt
     9721 taaagtgtta ttgttgggaa gattggcacg cgtcatcatt cagataccat tacaggtgat
     9781 tgctattttt tacttcatta aggcgttaga aaaacgacac gtttttgata gaatgaggct
     9841 tagataatat cgatggatgc tacaaaaaga ggttgaacac ggtatgaaac gcgctacaat
     9901 cgttaaacaa ataagtctaa cttttctatt gcacttcaag tctagttcaa ccttttttaa
     9961 tattaactgg ccttattatg actgcggaaa aacaatttgg gtatcgatgg ttgagttggt
    10021 acccagcaaa ataaaagagc ggctatgtgg tgggcatgat aattccctta gcagctaaat
    10081 tgcggacaca ttctgctaag tagctggcgt tgtgttctgg atagattggt gttgttaatg
    10141 caataggagt gaggtgatca taaggcgggc aaaactgccc acgataattt ggatcatacc
    10201 atattttatt aggatgatag ccgcgaagtt gcatttcatc catcactaat acatgaaatt
    10261 gatacaactt gtaaggggaa tatttgaaaa cataattaac ggttgcatga tttttacccc
    10321 aaccattgcc tttcaatgcg gcaagctcac ggtgttgacc tagtaattgt tgtcgtggta
    10381 attgatggat taattgttca tgccatagac gcataggcca cactccctta tcgaatttta
    10441 aaattaacag gtgaatatta aaaggaccaa ctcatcatta tgatgccgaa tatactgata
    10501 cttttgaacg ggtgatgatt gtaaacgacg gatagttaaa gtgaatattc gcaattatta
    10561 tagcatagcg aattgatcaa tagtttagta caagatcaaa aaaacggcca tagcaacaac
    10621 tgatatgatc aaacattcct tagaatgctt accttgaaag ttgggttgag taattaaaaa
    10681 taatattatt ttatgttgtg ttagcagcag ttcttaattt tgatcacagc ggtgtttgat
    10741 agatgtttga cggtatgcaa ataaaattat tgttctgata aaaggaatca atgattaata
    10801 atcttgagcg tcatttttcg aatcatggcg tttttatatt acaatggtcc tagaaaaagt
    10861 aaagttatgg aggcgattaa atgagtgatt tggatcagac aaacaactat cgatacgtca
    10921 ttgttggtgg cggaatggtt gctggctatg ccatcaaggg aattcgacag gaagatccag
    10981 agggcgcaat cttagttatt tcgcaagagg cggatgttcc gtatgaacgg ccggcactga
    11041 gtaaaaagct atggctagat gatgagttta ctgaagagaa cattcggatt ggtgctgaag
    11101 attatcctaa tgtgactttt aagttcaaga caacggttac ggctattaat cggcaagata
    11161 aggtcattac attgactgat agtgagcaaa tcaagtatga acagctattg ctggcaactg
    11221 gcggagaacc tcgacaaatc cagggacctg ctgatccaca tgtgctagtc tttagacagt
    11281 ggtcagatta tcgcaagtta cgtaaattta gtggtccgaa caagcgagtt gtgatcattg
    11341 gtggtggata tgttggtaca gagctcgcat cgtcactgac tcaaaatggg actaaagtta
    11401 cgatgatttt tccagaaaaa gcgctgggcg agggtaaatt tcctgagtcc attcgggctg
    11461 agtatgaagc aacgttcaaa cgtaatggtg tcacactgat gagtggtcag tttgtccaat
    11521 catatcaacg ccaaggtgat catttgactc tattgacaaa ggatggtacg gcgatcgcag
    11581 ccgatacgat tattgttggg ttaggtgtca cgccgcggat tagtttggct gaagatagta
    11641 gtttggattt agctgatggt ggtgtgaaag ttgatgagta tctcaatact agtgacccag
    11701 ccatctggtc tgctggagat attgcctctt atccagatca catcttgggt cggcaacgga
    11761 ttgagcacgt ggaccacgcc cgactttctg gtgaattagt tggccgtaat atggcaggtg
    11821 ctcacatgag ctatcaacat accccatact tctattccat gatttttgat atttcctggc
    11881 aagcaatcgg taatattgat cctaaattgc aattgatttt tgatcggcga acgcatggat
    11941 cgcttgttta tttcatagat gccggtaagt tagttggtgt tttagtttgg aatgttaagg
    12001 tgaaccttga tgatgttcgc gcattgcttg cgaacgctcc agccacggat gatttggtag
    12061 gttccattcg agagcaagag ggatagtatc tggatgagac atttgcgcta ttgtgaatgt
    12121 acgtcaggac aaatcgacca tcattaacga tggttcagta acaaatgaaa agtcagccgt
    12181 aagttatttt gcttacgact ggcttttatt tttaatgtct aaaattataa ggcgctaatg
    12241 aagcgttgtg cgatttcgag tggccgggtg atggcggccc cgacaacgac cgcgtggcac
    12301 cctaagtcaa ggcaacgttt catcttctcg ggcgtatcca ccttaccttc agcgataaca
    12361 gggcgtgatg tggcttggag gacttccttt aagtaggcga agtcattatc agcaatgttg
    12421 gcaccagtcg tggctggtgt gtagccgtgc atcgtggtcc caataatatc aaaccctaac
    12481 ctatccgcta ctttgacgtt ctcgatggta tcagtatcag ccatcaagag ggtatcaggg
    12541 aattctgttc gcatggtggc cacaatctcc gccaattttt caccgttagg acgcggctga
    12601 cccgtgacat cgcaggcaac tacggcacag cccgtagcag caacggctcg catctctttg
    12661 attgttggcg tgatgtaaac aggtgagtcg ggatagtcga ctttgcttaa accaatgagc
    12721 ggtagatcaa cttcgtcttg aatggcctga atatcaacaa cggaattagc gcgaataccc
    12781 gcggccccag cttccttagc ggcaagggcc attcgtgaca taataaatga actatgcagt
    12841 ggttcattag gtaacgcctg acacgagata attaatgatc ccttaactgt atttaagaat
    12901 gtatttttca taaaaaagac cgctttctac tagggtcc
//
