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ORF_ID	ortholog	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKDIFGKN_00001	1291743.LOSG293_490040	3.67e-41	-	-	-	-	-	-	-	-
HKDIFGKN_00002	1423815.BACR01000049_gene2337	2.06e-103	-	-	-	L	-	-	-	Integrase
HKDIFGKN_00004	1122149.BACN01000100_gene1979	2.17e-08	-	-	-	L	-	-	-	Integrase
HKDIFGKN_00005	1122149.BACN01000104_gene2005	8.83e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKDIFGKN_00006	1122149.BACN01000104_gene2004	4.68e-67	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HKDIFGKN_00007	1231336.L248_2047	3.45e-28	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKDIFGKN_00008	1133569.AHYZ01000024_gene420	6.86e-81	-	-	-	-	-	-	-	-
HKDIFGKN_00009	1423815.BACR01000049_gene2339	3.5e-220	-	-	-	L	-	-	-	Initiator Replication protein
HKDIFGKN_00010	220668.45723542	1.35e-214	-	-	-	L	-	-	-	Replication protein
HKDIFGKN_00011	1071400.347309353	5.24e-176	mob	-	-	D	-	-	-	Plasmid recombination enzyme
HKDIFGKN_00012	60520.HR47_10420	2.96e-183	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HKDIFGKN_00013	1423816.BACQ01000022_gene746	2.13e-05	-	-	-	-	-	-	-	-
HKDIFGKN_00014	220668.lp_2464	1.19e-257	-	-	-	S	-	-	-	Phage portal protein
HKDIFGKN_00015	60520.HR47_10405	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HKDIFGKN_00016	220668.lp_2462	5.85e-56	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKDIFGKN_00017	1400520.LFAB_05370	5.17e-72	-	-	-	-	-	-	-	-
HKDIFGKN_00018	60520.HR47_09180	2.1e-41	-	-	-	-	-	-	-	-
HKDIFGKN_00021	220668.lp_2476	4.09e-15	-	-	-	-	-	-	-	-
HKDIFGKN_00023	60520.HR47_10455	2.99e-158	-	-	-	L	-	-	-	DNA replication protein
HKDIFGKN_00024	701521.PECL_590	3.49e-136	-	-	-	S	ko:K06919	-	ko00000	DNA primase
HKDIFGKN_00025	1400520.LFAB_15680	3.2e-24	-	-	-	-	-	-	-	-
HKDIFGKN_00026	60520.HR47_10440	1.53e-35	-	-	-	-	-	-	-	-
HKDIFGKN_00027	60520.HR47_10435	6.81e-64	-	-	-	S	-	-	-	Head-tail joining protein
HKDIFGKN_00028	220668.lp_2469	1.62e-83	-	-	-	L	-	-	-	HNH endonuclease
HKDIFGKN_00029	1400520.LFAB_00205	2.05e-102	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HKDIFGKN_00030	220668.lp_1197	6.93e-163	epsB	-	-	M	-	-	-	biosynthesis protein
HKDIFGKN_00031	1400520.LFAB_09265	1.6e-161	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKDIFGKN_00032	1400520.LFAB_09260	1.68e-174	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKDIFGKN_00033	1400520.LFAB_09255	1.62e-151	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HKDIFGKN_00034	1400520.LFAB_09250	1.16e-265	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKDIFGKN_00035	1400520.LFAB_09245	5.72e-196	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HKDIFGKN_00036	1400520.LFAB_09240	4.2e-246	-	-	-	S	-	-	-	EpsG family
HKDIFGKN_00037	1033837.WANG_1780	4.51e-128	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKDIFGKN_00038	1033837.WANG_1737	2e-88	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKDIFGKN_00039	1033837.WANG_1737	1.83e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKDIFGKN_00040	220668.lp_0925	1.61e-37	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HKDIFGKN_00041	1400520.LFAB_17400	3.37e-123	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HKDIFGKN_00042	1400520.LFAB_17430	7.55e-53	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HKDIFGKN_00043	278197.PEPE_1049	3.57e-65	-	-	-	M	-	-	-	domain, Protein
HKDIFGKN_00044	1400520.LFAB_17405	2.07e-80	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKDIFGKN_00045	1123359.AUIQ01000090_gene154	2.26e-130	-	-	-	L	-	-	-	Resolvase, N terminal domain
HKDIFGKN_00047	1122149.BACN01000113_gene2019	2.71e-300	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKDIFGKN_00048	557436.Lreu_1346	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HKDIFGKN_00049	1138822.PL11_10595	3.99e-46	-	-	-	L	-	-	-	Integrase
HKDIFGKN_00050	1138822.PL11_10630	5.97e-42	-	-	-	L	-	-	-	Integrase
HKDIFGKN_00051	1423815.BACR01000049_gene2337	2.8e-101	-	-	-	L	-	-	-	Integrase
HKDIFGKN_00052	1133569.AHYZ01000091_gene708	1.74e-31	-	-	-	-	-	-	-	-
HKDIFGKN_00053	60520.HR47_09180	4.86e-101	-	-	-	-	-	-	-	-
HKDIFGKN_00054	1139219.I569_00539	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_00055	1139219.I569_00538	5.95e-110	-	-	-	S	-	-	-	Membrane
HKDIFGKN_00056	1045004.OKIT_0536	3.14e-191	-	-	-	-	-	-	-	-
HKDIFGKN_00057	1423816.BACQ01000038_gene1588	8.47e-87	-	-	-	-	-	-	-	-
HKDIFGKN_00058	1291743.LOSG293_220250	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKDIFGKN_00059	797515.HMPREF9103_01821	3.6e-42	-	-	-	-	-	-	-	-
HKDIFGKN_00060	1400520.LFAB_17305	1.67e-252	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKDIFGKN_00061	220668.lp_0941	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKDIFGKN_00062	203123.OEOE_0093	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	C-terminal repeat of topoisomerase
HKDIFGKN_00069	883168.HMPREF9318_00132	2.81e-154	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HKDIFGKN_00072	1140001.I571_02880	3.21e-32	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKDIFGKN_00075	220668.lp_2455	2.69e-278	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKDIFGKN_00077	390333.Ldb1396	4.05e-43	-	-	-	-	-	-	-	-
HKDIFGKN_00084	1136177.KCA1_2039	3.77e-86	-	-	-	-	-	-	-	-
HKDIFGKN_00085	220668.lp_2449	4.71e-98	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HKDIFGKN_00086	220668.lp_0631	4.65e-52	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_00089	60520.HR47_13635	3.26e-72	-	-	-	-	-	-	-	-
HKDIFGKN_00090	60520.HR47_13630	2.59e-102	-	-	-	-	-	-	-	-
HKDIFGKN_00092	220668.lp_2441	1.91e-106	-	-	-	-	-	-	-	-
HKDIFGKN_00093	755164.D6PSU1_9CAUD	1.46e-80	-	-	-	S	-	-	-	ERF superfamily
HKDIFGKN_00094	755164.D6PSU2_9CAUD	2.85e-59	-	-	-	S	-	-	-	Single-strand binding protein family
HKDIFGKN_00095	220668.lp_0643	4.05e-214	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
HKDIFGKN_00096	60520.HR47_13590	1.88e-66	-	-	-	-	-	-	-	-
HKDIFGKN_00097	1423807.BACO01000085_gene2467	3.69e-77	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
HKDIFGKN_00098	220668.lp_2434	1.5e-79	-	-	-	-	-	-	-	-
HKDIFGKN_00099	220668.lp_2433	4.32e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HKDIFGKN_00101	220668.lp_2432	9.2e-08	-	-	-	-	-	-	-	-
HKDIFGKN_00102	220668.lp_0656	3.86e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HKDIFGKN_00105	1291743.LOSG293_110420	6.68e-26	-	-	-	S	-	-	-	KTSC domain
HKDIFGKN_00107	220668.lp_2425	2.19e-31	-	-	-	-	-	-	-	-
HKDIFGKN_00108	797515.HMPREF9103_00825	1.05e-39	-	-	-	-	-	-	-	-
HKDIFGKN_00110	220668.lp_2423	3.89e-89	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HKDIFGKN_00111	220668.lp_0661	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HKDIFGKN_00112	220668.lp_2420	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HKDIFGKN_00113	220668.lp_2419	5.37e-221	-	-	-	S	-	-	-	Phage Mu protein F like protein
HKDIFGKN_00114	220668.lp_2418	2.08e-107	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HKDIFGKN_00115	220668.lp_2417	7.2e-240	gpG	-	-	-	-	-	-	-
HKDIFGKN_00116	220668.lp_2416	3.37e-79	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKDIFGKN_00117	220668.lp_0667	2.6e-65	-	-	-	-	-	-	-	-
HKDIFGKN_00118	220668.lp_2414	9.66e-123	-	-	-	-	-	-	-	-
HKDIFGKN_00119	220668.lp_2413	1.05e-85	-	-	-	-	-	-	-	-
HKDIFGKN_00120	220668.lp_2412	1.21e-122	-	-	-	-	-	-	-	-
HKDIFGKN_00121	220668.lp_2411	1.6e-108	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HKDIFGKN_00123	220668.lp_0673	0.0	-	-	-	D	-	-	-	domain protein
HKDIFGKN_00124	220668.lp_2408	1.19e-200	-	-	-	S	-	-	-	Phage tail protein
HKDIFGKN_00125	220668.lp_2407	2.56e-256	-	-	-	M	-	-	-	Prophage endopeptidase tail
HKDIFGKN_00128	1127131.WEISSC39_10845	2.57e-55	-	-	-	-	-	-	-	-
HKDIFGKN_00130	1136177.KCA1_1485	1.32e-144	-	-	-	KT	-	-	-	Purine catabolism regulatory protein-like family
HKDIFGKN_00131	1136177.KCA1_1487	2.8e-210	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
HKDIFGKN_00132	1136177.KCA1_1488	1.06e-203	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HKDIFGKN_00133	1136177.KCA1_1489	1.07e-254	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
HKDIFGKN_00134	913848.AELK01000013_gene1302	1.56e-15	-	-	-	-	-	-	-	-
HKDIFGKN_00135	913848.AELK01000251_gene1265	1.15e-07	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HKDIFGKN_00136	220668.lp_0550	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKDIFGKN_00137	220668.lp_0549	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKDIFGKN_00138	220668.lp_0548	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKDIFGKN_00139	220668.lp_0547	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKDIFGKN_00140	220668.lp_0546	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKDIFGKN_00141	220668.lp_0545	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKDIFGKN_00142	220668.lp_0543	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HKDIFGKN_00143	220668.lp_0542	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HKDIFGKN_00145	220668.lp_0541	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HKDIFGKN_00146	220668.lp_0540	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKDIFGKN_00147	220668.lp_0539	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKDIFGKN_00148	220668.lp_0538	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKDIFGKN_00149	220668.lp_0537	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKDIFGKN_00150	220668.lp_0536	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKDIFGKN_00151	220668.lp_0535	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HKDIFGKN_00152	220668.lp_0533	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HKDIFGKN_00153	220668.lp_0532	1.52e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKDIFGKN_00154	220668.lp_0531	3.52e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HKDIFGKN_00155	220668.lp_0530	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HKDIFGKN_00156	220668.lp_0529	1.96e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKDIFGKN_00157	220668.lp_0528	2.18e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKDIFGKN_00158	220668.lp_0527	3.7e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKDIFGKN_00159	220668.lp_0526	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKDIFGKN_00160	60520.HR47_08560	5.79e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKDIFGKN_00161	1136177.KCA1_0443	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDIFGKN_00162	60520.HR47_08570	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HKDIFGKN_00163	220668.lp_0525	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKDIFGKN_00164	1136177.KCA1_0440	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HKDIFGKN_00165	220668.lp_0523	1.67e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKDIFGKN_00166	220668.lp_0522	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKDIFGKN_00167	220668.lp_0520	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKDIFGKN_00168	220668.lp_0518	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKDIFGKN_00169	220668.lp_0517	1.84e-189	-	-	-	-	-	-	-	-
HKDIFGKN_00170	220668.lp_0516	1.6e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKDIFGKN_00171	220668.lp_0515	8.87e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKDIFGKN_00172	220668.lp_0514	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HKDIFGKN_00173	220668.lp_0513	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
HKDIFGKN_00174	1136177.KCA1_0423	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKDIFGKN_00175	220668.lp_0511	1.26e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKDIFGKN_00176	220668.lp_0510	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKDIFGKN_00177	220668.lp_0509	4.01e-36	-	-	-	-	-	-	-	-
HKDIFGKN_00178	220668.lp_0507	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HKDIFGKN_00179	220668.lp_0506	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKDIFGKN_00180	220668.lp_0505	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HKDIFGKN_00181	220668.lp_0502	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HKDIFGKN_00182	220668.lp_0501	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKDIFGKN_00183	220668.lp_0481	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKDIFGKN_00184	1136177.KCA1_0413	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKDIFGKN_00185	220668.lp_0479	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HKDIFGKN_00186	220668.lp_0477	1.14e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HKDIFGKN_00187	220668.lp_0476	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HKDIFGKN_00188	220668.lp_0475	7.18e-192	yxeH	-	-	S	-	-	-	hydrolase
HKDIFGKN_00190	220668.lp_3579	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HKDIFGKN_00191	220668.lp_3580	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKDIFGKN_00192	60520.HR47_10820	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKDIFGKN_00193	60520.HR47_10815	9.62e-19	-	-	-	-	-	-	-	-
HKDIFGKN_00194	60520.HR47_10810	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HKDIFGKN_00195	220668.lp_3583	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HKDIFGKN_00197	220668.lp_3586	1.89e-254	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKDIFGKN_00198	220668.lp_3587	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKDIFGKN_00199	220668.lp_3588	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_00200	220668.lp_3589	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKDIFGKN_00201	220668.lp_3652	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKDIFGKN_00202	220668.lp_3653	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HKDIFGKN_00203	220668.lp_3654	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HKDIFGKN_00204	220668.lp_3655	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HKDIFGKN_00205	220668.lp_3656	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HKDIFGKN_00206	220668.lp_3657	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HKDIFGKN_00207	220668.lp_3658	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HKDIFGKN_00208	220668.lp_3659	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKDIFGKN_00209	220668.lp_3660	4.52e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKDIFGKN_00210	220668.lp_3661	1.88e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKDIFGKN_00211	1136177.KCA1_2828	3.36e-06	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKDIFGKN_00212	585394.RHOM_04430	6.2e-09	-	-	-	-	-	-	-	-
HKDIFGKN_00213	1121864.OMO_00392	2.2e-26	-	-	-	-	-	-	-	-
HKDIFGKN_00214	220668.lp_3662	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKDIFGKN_00215	220668.lp_3663	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HKDIFGKN_00216	220668.lp_3664	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HKDIFGKN_00217	220668.lp_3665	2.14e-132	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HKDIFGKN_00218	220668.lp_3666	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HKDIFGKN_00219	220668.lp_3668	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDIFGKN_00220	220668.lp_3669	3.3e-202	degV1	-	-	S	-	-	-	DegV family
HKDIFGKN_00221	220668.lp_3672	2.89e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HKDIFGKN_00222	220668.lp_3673	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKDIFGKN_00224	220668.lp_3675	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKDIFGKN_00225	220668.lp_3676	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_00227	220668.lp_3678	2.13e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKDIFGKN_00228	220668.lp_3679	1.66e-144	-	-	-	S	-	-	-	Cell surface protein
HKDIFGKN_00229	220668.lp_3681	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKDIFGKN_00230	220668.lp_3682	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKDIFGKN_00231	220668.lp_3683	2.14e-155	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HKDIFGKN_00232	220668.lp_3684	3.75e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HKDIFGKN_00233	220668.lp_3686	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKDIFGKN_00234	220668.lp_3687	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKDIFGKN_00235	1136177.KCA1_3018	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKDIFGKN_00236	220668.lp_0001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKDIFGKN_00237	220668.lp_0002	4.74e-266	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKDIFGKN_00238	220668.lp_0004	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HKDIFGKN_00239	220668.lp_0005	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKDIFGKN_00240	220668.lp_0006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKDIFGKN_00241	220668.lp_0007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKDIFGKN_00242	1136177.KCA1_0007	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKDIFGKN_00243	60520.HR47_10595	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKDIFGKN_00244	220668.lp_0011	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKDIFGKN_00245	220668.lp_0012	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKDIFGKN_00246	220668.lp_0013	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKDIFGKN_00247	220668.lp_0014	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKDIFGKN_00248	220668.lp_0015	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_00249	220668.lp_0016	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKDIFGKN_00250	220668.lp_0017	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKDIFGKN_00252	220668.lp_0018	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKDIFGKN_00253	220668.lp_0020	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKDIFGKN_00254	220668.lp_0021	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKDIFGKN_00255	220668.lp_0022	2.38e-250	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HKDIFGKN_00256	220668.lp_0023	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKDIFGKN_00257	220668.lp_0024	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKDIFGKN_00258	220668.lp_0025	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKDIFGKN_00260	220668.lp_0026	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKDIFGKN_00261	220668.lp_0027	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKDIFGKN_00262	220668.lp_0028	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HKDIFGKN_00263	220668.lp_0030	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HKDIFGKN_00264	220668.lp_0031	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HKDIFGKN_00265	220668.lp_0032	2.54e-50	-	-	-	-	-	-	-	-
HKDIFGKN_00267	1136177.KCA1_0029	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKDIFGKN_00268	220668.lp_0037	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKDIFGKN_00269	220668.lp_0038	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HKDIFGKN_00270	220668.lp_0039	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HKDIFGKN_00271	220668.lp_0041	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HKDIFGKN_00272	220668.lp_0043	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HKDIFGKN_00273	220668.lp_0045	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKDIFGKN_00274	220668.lp_0046	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_00275	220668.lp_0047	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HKDIFGKN_00276	60520.HR47_05810	8.48e-215	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HKDIFGKN_00277	220668.lp_0048	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HKDIFGKN_00278	220668.lp_0050	2.33e-157	pnb	-	-	C	-	-	-	nitroreductase
HKDIFGKN_00279	220668.lp_0052	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HKDIFGKN_00280	220668.lp_0053	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HKDIFGKN_00281	220668.lp_0055	0.0	-	-	-	C	-	-	-	FMN_bind
HKDIFGKN_00282	220668.lp_0056	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKDIFGKN_00283	220668.lp_0057	1.46e-204	-	-	-	K	-	-	-	LysR family
HKDIFGKN_00284	220668.lp_0058	2.49e-95	-	-	-	C	-	-	-	FMN binding
HKDIFGKN_00285	220668.lp_0059	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKDIFGKN_00286	220668.lp_0060	4.06e-211	-	-	-	S	-	-	-	KR domain
HKDIFGKN_00287	220668.lp_0061	2.6e-199	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HKDIFGKN_00288	220668.lp_0062	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HKDIFGKN_00289	220668.lp_0063	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HKDIFGKN_00290	220668.lp_0066	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKDIFGKN_00291	220668.lp_0067	7.63e-249	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKDIFGKN_00292	220668.lp_0068	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKDIFGKN_00293	220668.lp_0069	1.97e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKDIFGKN_00294	60520.HR47_05895	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HKDIFGKN_00295	220668.lp_0072	1.65e-106	-	-	-	S	-	-	-	ASCH
HKDIFGKN_00296	220668.lp_0073	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HKDIFGKN_00297	220668.lp_0074	1.67e-220	-	-	-	K	-	-	-	WYL domain
HKDIFGKN_00298	220668.lp_0075	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKDIFGKN_00299	220668.lp_0076	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HKDIFGKN_00300	220668.lp_0077	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HKDIFGKN_00301	220668.lp_0077	1.15e-80	-	-	-	S	-	-	-	Protein of unknown function
HKDIFGKN_00302	220668.lp_0078	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HKDIFGKN_00303	220668.lp_0080	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HKDIFGKN_00304	220668.lp_0081	1.27e-64	-	-	-	S	-	-	-	DJ-1/PfpI family
HKDIFGKN_00305	220668.lp_0082	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKDIFGKN_00306	220668.lp_0083	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDIFGKN_00307	220668.lp_0085	3.61e-283	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HKDIFGKN_00308	220668.lp_0088	1.04e-27	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKDIFGKN_00309	220668.lp_0088	5.61e-173	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKDIFGKN_00310	220668.lp_0089	2.23e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HKDIFGKN_00311	220668.lp_0091	2.38e-99	-	-	-	-	-	-	-	-
HKDIFGKN_00312	220668.lp_0092	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKDIFGKN_00313	220668.lp_0096	4.85e-180	-	-	-	-	-	-	-	-
HKDIFGKN_00314	60520.HR47_05995	4.07e-05	-	-	-	-	-	-	-	-
HKDIFGKN_00315	220668.lp_0098	6.61e-183	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HKDIFGKN_00316	220668.lp_0099	1.67e-54	-	-	-	-	-	-	-	-
HKDIFGKN_00317	220668.lp_0100	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_00318	220668.lp_0101	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKDIFGKN_00319	220668.lp_0102	1.06e-234	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HKDIFGKN_00320	220668.lp_0103	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HKDIFGKN_00321	60520.HR47_06030	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HKDIFGKN_00322	220668.lp_0105	8.84e-161	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HKDIFGKN_00323	220668.lp_0106	3.93e-177	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKDIFGKN_00324	220668.lp_0107	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HKDIFGKN_00325	220668.lp_0108	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKDIFGKN_00326	220668.lp_0109	2.6e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HKDIFGKN_00327	220668.lp_0111	7.11e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKDIFGKN_00328	220668.lp_0113	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKDIFGKN_00329	220668.lp_0114	7.44e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKDIFGKN_00330	220668.lp_0116	2.65e-257	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HKDIFGKN_00331	220668.lp_0117	2.39e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKDIFGKN_00332	220668.lp_0118	0.0	-	-	-	L	-	-	-	HIRAN domain
HKDIFGKN_00333	220668.lp_0119	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKDIFGKN_00334	220668.lp_0120	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKDIFGKN_00335	220668.lp_0121	5.18e-159	-	-	-	-	-	-	-	-
HKDIFGKN_00336	220668.lp_0122	2.07e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HKDIFGKN_00337	220668.lp_0124	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKDIFGKN_00338	220668.lp_0125	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
HKDIFGKN_00339	220668.lp_0126	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HKDIFGKN_00340	60520.HR47_06130	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKDIFGKN_00341	220668.lp_0128	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_00342	60520.HR47_06140	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKDIFGKN_00343	220668.lp_0130	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKDIFGKN_00344	220668.lp_0132	3.63e-288	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKDIFGKN_00345	220668.lp_0133	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDIFGKN_00346	220668.lp_0134	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HKDIFGKN_00348	220668.lp_0136	2.16e-204	morA	-	-	S	-	-	-	reductase
HKDIFGKN_00349	220668.lp_0137	3.76e-110	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HKDIFGKN_00350	220668.lp_0137	2.24e-50	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HKDIFGKN_00351	220668.lp_0138	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HKDIFGKN_00352	220668.lp_0139	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKDIFGKN_00353	220668.lp_0141	7.45e-103	-	-	-	-	-	-	-	-
HKDIFGKN_00354	220668.lp_0145	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_00355	220668.lp_0146	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HKDIFGKN_00356	220668.lp_0148	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKDIFGKN_00357	220668.lp_0149	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_00358	220668.lp_0150	2.11e-127	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HKDIFGKN_00360	220668.lp_0152	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKDIFGKN_00361	220668.lp_0154	1.19e-71	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKDIFGKN_00362	220668.lp_0155	6.08e-180	-	-	-	-	-	-	-	-
HKDIFGKN_00363	220668.lp_0156	1.1e-191	-	-	-	-	-	-	-	-
HKDIFGKN_00364	220668.lp_0158	3.37e-115	-	-	-	-	-	-	-	-
HKDIFGKN_00365	220668.lp_0159	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HKDIFGKN_00366	220668.lp_0160	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_00367	220668.lp_0161	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HKDIFGKN_00368	220668.lp_0162	1.33e-149	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HKDIFGKN_00369	220668.lp_0163	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HKDIFGKN_00370	220668.lp_0164	1.67e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HKDIFGKN_00372	220668.lp_0165	2.16e-120	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_00373	220668.lp_0166	7.86e-242	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HKDIFGKN_00374	220668.lp_0168	3.72e-237	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HKDIFGKN_00375	220668.lp_0169	7.88e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HKDIFGKN_00376	220668.lp_0170	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HKDIFGKN_00377	220668.lp_0171	2.32e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKDIFGKN_00378	220668.lp_0172	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKDIFGKN_00379	220668.lp_0173	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKDIFGKN_00380	220668.lp_0174	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKDIFGKN_00381	220668.lp_0175	3.85e-298	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKDIFGKN_00382	220668.lp_0176	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDIFGKN_00383	220668.lp_0177	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_00384	220668.lp_0178	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HKDIFGKN_00385	220668.lp_0179	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HKDIFGKN_00386	220668.lp_0180	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKDIFGKN_00387	220668.lp_0181	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKDIFGKN_00388	220668.lp_0182	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HKDIFGKN_00389	220668.lp_0183	1.17e-60	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HKDIFGKN_00390	220668.lp_0184	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKDIFGKN_00391	278197.PEPE_0517	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKDIFGKN_00392	278197.PEPE_0517	1.42e-21	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKDIFGKN_00393	220668.lp_0185	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDIFGKN_00394	220668.lp_0187	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKDIFGKN_00395	220668.lp_0188	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKDIFGKN_00396	220668.lp_0189	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKDIFGKN_00397	220668.lp_0190	4.71e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKDIFGKN_00398	220668.lp_0192	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKDIFGKN_00399	220668.lp_0193	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKDIFGKN_00400	220668.lp_0194	2.44e-212	mleR	-	-	K	-	-	-	LysR substrate binding domain
HKDIFGKN_00401	220668.lp_0197	0.0	-	-	-	M	-	-	-	domain protein
HKDIFGKN_00403	220668.lp_0199	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKDIFGKN_00404	220668.lp_0200	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKDIFGKN_00405	220668.lp_0201	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKDIFGKN_00406	220668.lp_0202	2.65e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKDIFGKN_00407	220668.lp_0203	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKDIFGKN_00408	220668.lp_0204	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKDIFGKN_00409	220668.lp_0205	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HKDIFGKN_00410	60520.HR47_03225	4.12e-228	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HKDIFGKN_00411	220668.lp_0207	6.33e-46	-	-	-	-	-	-	-	-
HKDIFGKN_00412	220668.lp_0208	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HKDIFGKN_00413	220668.lp_0209	4.37e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HKDIFGKN_00414	220668.lp_0210	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKDIFGKN_00415	1136177.KCA1_0189	3.81e-18	-	-	-	-	-	-	-	-
HKDIFGKN_00416	220668.lp_0213	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKDIFGKN_00417	220668.lp_0214	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKDIFGKN_00418	314315.LCA_0141	3.59e-126	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HKDIFGKN_00419	797515.HMPREF9103_01322	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKDIFGKN_00420	1400520.LFAB_17405	1.15e-77	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKDIFGKN_00421	1400520.LFAB_17400	1.67e-123	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HKDIFGKN_00422	768486.EHR_02535	2.93e-73	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
HKDIFGKN_00423	220668.lp_2399	2.38e-49	-	-	-	S	-	-	-	Bacteriophage holin
HKDIFGKN_00424	1400520.LFAB_09020	3.45e-45	-	-	-	S	-	-	-	Haemolysin XhlA
HKDIFGKN_00425	1136177.KCA1_1105	1.39e-258	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKDIFGKN_00426	1423807.BACO01000096_gene2531	3.4e-33	-	-	-	-	-	-	-	-
HKDIFGKN_00427	220668.lp_2404	8.38e-77	-	-	-	-	-	-	-	-
HKDIFGKN_00430	60520.HR47_09980	3.72e-106	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKDIFGKN_00431	511437.Lbuc_2396	6.43e-49	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKDIFGKN_00433	1114972.AUAW01000027_gene729	7.47e-43	-	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
HKDIFGKN_00434	1114972.AUAW01000027_gene728	1.28e-153	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKDIFGKN_00435	1114972.AUAW01000027_gene727	6.72e-242	galM1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKDIFGKN_00436	1071400.LBUCD034_2335	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKDIFGKN_00437	1114972.AUAW01000027_gene725	3.74e-82	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKDIFGKN_00438	1114972.AUAW01000027_gene724	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKDIFGKN_00439	1114972.AUAW01000027_gene723	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKDIFGKN_00440	1114972.AUAW01000027_gene720	1.47e-242	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKDIFGKN_00441	1423780.LOT_2221	0.0	-	-	-	L	-	-	-	MobA MobL family protein
HKDIFGKN_00442	1400520.LFAB_17315	5.67e-36	-	-	-	-	-	-	-	-
HKDIFGKN_00443	1138822.PL11_10670	3.57e-54	-	-	-	-	-	-	-	-
HKDIFGKN_00444	1423780.LOT_2224	6.43e-103	-	-	-	-	-	-	-	-
HKDIFGKN_00445	1045004.OKIT_0519	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HKDIFGKN_00446	585524.HMPREF0493_1297	4.73e-66	repA	-	-	S	-	-	-	Replication initiator protein A
HKDIFGKN_00448	1138822.PL11_10490	2.13e-188	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HKDIFGKN_00449	1138822.PL11_10485	2.87e-76	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HKDIFGKN_00450	1114972.AUAW01000027_gene738	3.09e-79	-	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_00452	1045854.WKK_00090	3.37e-144	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HKDIFGKN_00453	278197.PEPE_0498	6.04e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKDIFGKN_00456	1400520.LFAB_13530	9.52e-49	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HKDIFGKN_00457	1400520.LFAB_13535	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKDIFGKN_00458	1400520.LFAB_13540	5.49e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKDIFGKN_00459	1114972.AUAW01000027_gene737	3.44e-120	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HKDIFGKN_00460	334390.LAF_0686	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_00461	334390.LAF_0685	6.28e-226	-	-	-	-	-	-	-	-
HKDIFGKN_00462	1138822.PL11_10520	3.46e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HKDIFGKN_00463	220668.lp_3577	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HKDIFGKN_00464	1229758.C270_04340	1.06e-16	-	-	-	-	-	-	-	-
HKDIFGKN_00465	220668.lp_3575	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HKDIFGKN_00466	220668.lp_3573	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HKDIFGKN_00467	220668.lp_3572	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HKDIFGKN_00468	220668.lp_3571	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKDIFGKN_00469	220668.lp_3568	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HKDIFGKN_00470	220668.lp_3567	4.66e-197	nanK	-	-	GK	-	-	-	ROK family
HKDIFGKN_00471	220668.lp_3566	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKDIFGKN_00472	220668.lp_3565	2.32e-262	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKDIFGKN_00473	220668.lp_3563	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKDIFGKN_00474	220668.lp_3562	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKDIFGKN_00475	220668.lp_3561	7.3e-210	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKDIFGKN_00476	220668.lp_3560	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKDIFGKN_00477	220668.lp_3559	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKDIFGKN_00478	60520.HR47_10910	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKDIFGKN_00479	60520.HR47_10915	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HKDIFGKN_00480	220668.lp_3548	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKDIFGKN_00481	220668.lp_3547	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKDIFGKN_00482	220668.lp_3546	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKDIFGKN_00483	220668.lp_3545	8.72e-246	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HKDIFGKN_00484	220668.lp_3544	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKDIFGKN_00485	220668.lp_3543	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKDIFGKN_00486	220668.lp_3542	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKDIFGKN_00487	220668.lp_3541	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HKDIFGKN_00488	220668.lp_3540	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKDIFGKN_00489	220668.lp_3539	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKDIFGKN_00490	220668.lp_3538	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKDIFGKN_00491	220668.lp_3537	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
HKDIFGKN_00492	220668.lp_3536	1.91e-235	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKDIFGKN_00493	1114972.AUAW01000010_gene933	3.77e-19	-	-	-	S	-	-	-	Mor transcription activator family
HKDIFGKN_00495	1423775.BAMN01000011_gene634	6.42e-26	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKDIFGKN_00497	1267003.KB911387_gene1880	9.61e-141	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HKDIFGKN_00501	60520.HR47_05785	1.14e-50	-	-	-	-	-	-	-	-
HKDIFGKN_00502	60520.HR47_05780	5.09e-149	-	-	-	Q	-	-	-	Methyltransferase domain
HKDIFGKN_00503	1400520.LFAB_13655	5.91e-167	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKDIFGKN_00504	220668.lp_3171	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKDIFGKN_00505	220668.lp_3172	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HKDIFGKN_00506	220668.lp_3173	2.92e-143	-	-	-	-	-	-	-	-
HKDIFGKN_00507	220668.lp_3174	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKDIFGKN_00508	220668.lp_3175	3.32e-210	-	-	-	-	-	-	-	-
HKDIFGKN_00509	220668.lp_3176	5.33e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HKDIFGKN_00510	220668.lp_3177	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HKDIFGKN_00511	220668.lp_3178	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HKDIFGKN_00512	220668.lp_3179	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKDIFGKN_00513	220668.lp_3180	2.12e-72	-	-	-	-	-	-	-	-
HKDIFGKN_00514	60520.HR47_05710	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKDIFGKN_00515	1136177.KCA1_2610	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HKDIFGKN_00516	220668.lp_3185	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HKDIFGKN_00517	220668.lp_3187	6.77e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKDIFGKN_00518	220668.lp_3189	3.1e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKDIFGKN_00519	220668.lp_3190	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HKDIFGKN_00520	220668.lp_3191	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HKDIFGKN_00521	220668.lp_3192	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HKDIFGKN_00522	220668.lp_3193	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKDIFGKN_00523	220668.lp_3194	1.42e-269	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKDIFGKN_00524	220668.lp_3195	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HKDIFGKN_00525	220668.lp_3196	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKDIFGKN_00526	1136177.KCA1_2620	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HKDIFGKN_00527	220668.lp_3198	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKDIFGKN_00528	60520.HR47_05635	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HKDIFGKN_00529	220668.lp_3200	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKDIFGKN_00530	220668.lp_3201	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKDIFGKN_00531	220668.lp_3204	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HKDIFGKN_00532	60520.HR47_05615	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKDIFGKN_00533	220668.lp_3205	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_00534	220668.lp_3206	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HKDIFGKN_00535	220668.lp_3207	1.7e-301	-	-	-	EK	-	-	-	Aminotransferase, class I
HKDIFGKN_00536	220668.lp_3209	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKDIFGKN_00537	220668.lp_3210	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_00538	220668.lp_3211	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_00539	220668.lp_3214	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKDIFGKN_00540	220668.lp_3215	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
HKDIFGKN_00541	220668.lp_3216	8.2e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HKDIFGKN_00542	220668.lp_3217	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HKDIFGKN_00543	220668.lp_3218	1.13e-200	-	-	-	S	-	-	-	Putative adhesin
HKDIFGKN_00544	220668.lp_3219	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDIFGKN_00545	220668.lp_3220	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKDIFGKN_00546	220668.lp_3221	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HKDIFGKN_00547	220668.lp_3223	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HKDIFGKN_00548	220668.lp_3224	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HKDIFGKN_00549	220668.lp_3225	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_00550	220668.lp_3226	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKDIFGKN_00551	220668.lp_3227	6.26e-101	-	-	-	-	-	-	-	-
HKDIFGKN_00552	220668.lp_3236	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HKDIFGKN_00553	220668.lp_3237	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKDIFGKN_00554	220668.lp_3637	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKDIFGKN_00555	1545702.LACWKB8_1360	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HKDIFGKN_00556	1140002.I570_00535	1.35e-154	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HKDIFGKN_00557	1410674.JNKU01000043_gene113	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKDIFGKN_00558	1499684.CCNP01000018_gene968	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HKDIFGKN_00559	208596.CAR_c23420	1.5e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKDIFGKN_00560	220668.lp_3238	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HKDIFGKN_00561	220668.lp_3239	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
HKDIFGKN_00562	220668.lp_3240	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDIFGKN_00563	220668.lp_3241	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HKDIFGKN_00565	220668.lp_3244	2.01e-29	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKDIFGKN_00566	220668.lp_3244	2.15e-75	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKDIFGKN_00567	220668.lp_3245	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HKDIFGKN_00568	220668.lp_3246	1.16e-135	-	-	-	-	-	-	-	-
HKDIFGKN_00569	220668.lp_3247	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HKDIFGKN_00570	220668.lp_3248	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HKDIFGKN_00571	220668.lp_3250	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HKDIFGKN_00572	220668.lp_3251	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKDIFGKN_00573	220668.lp_3252	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKDIFGKN_00574	220668.lp_3254	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HKDIFGKN_00575	220668.lp_3255	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HKDIFGKN_00576	220668.lp_3256	1.28e-184	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HKDIFGKN_00577	220668.lp_3257	1.03e-34	-	-	-	-	-	-	-	-
HKDIFGKN_00578	220668.lp_3259	7.02e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HKDIFGKN_00579	220668.lp_3262	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HKDIFGKN_00580	220668.lp_3263	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HKDIFGKN_00581	220668.lp_3265	1.09e-196	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKDIFGKN_00582	220668.lp_3266	4.27e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKDIFGKN_00583	220668.lp_3267	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKDIFGKN_00584	220668.lp_3268	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
HKDIFGKN_00585	220668.lp_3269	5.2e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKDIFGKN_00586	220668.lp_3270	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKDIFGKN_00587	220668.lp_3271	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKDIFGKN_00588	220668.lp_3272	4.15e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKDIFGKN_00589	220668.lp_3273	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKDIFGKN_00591	220668.lp_3275	4.62e-107	-	-	-	-	-	-	-	-
HKDIFGKN_00592	220668.lp_3278	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HKDIFGKN_00594	220668.lp_3279	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKDIFGKN_00595	220668.lp_3280	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKDIFGKN_00596	220668.lp_3281	3.1e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKDIFGKN_00597	220668.lp_3283	1.38e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKDIFGKN_00598	60520.HR47_05270	1.63e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HKDIFGKN_00599	220668.lp_3285	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HKDIFGKN_00600	220668.lp_3286	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HKDIFGKN_00601	220668.lp_3287	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDIFGKN_00602	220668.lp_3288	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HKDIFGKN_00603	220668.lp_3292	8.03e-28	-	-	-	-	-	-	-	-
HKDIFGKN_00604	220668.lp_3293	4.57e-123	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKDIFGKN_00605	220668.lp_3294	5.59e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HKDIFGKN_00606	220668.lp_3295	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HKDIFGKN_00607	220668.lp_3296	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKDIFGKN_00608	220668.lp_3297	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HKDIFGKN_00609	220668.lp_3298	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKDIFGKN_00610	220668.lp_3299	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKDIFGKN_00611	220668.lp_3301	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HKDIFGKN_00612	220668.lp_3302	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKDIFGKN_00613	220668.lp_3303	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_00615	220668.lp_3305	4.54e-54	-	-	-	-	-	-	-	-
HKDIFGKN_00616	1291743.LOSG293_540090	2.92e-15	-	-	-	S	-	-	-	Initiator Replication protein
HKDIFGKN_00619	60520.HR47_09180	3.92e-45	-	-	-	-	-	-	-	-
HKDIFGKN_00621	1291743.LOSG293_490070	3.45e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKDIFGKN_00622	1291743.LOSG293_490060	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HKDIFGKN_00623	60520.HR47_14815	7.6e-139	-	-	-	L	-	-	-	Integrase
HKDIFGKN_00624	797515.HMPREF9103_01297	2.03e-67	-	-	-	-	-	-	-	-
HKDIFGKN_00625	1400520.LFAB_17310	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HKDIFGKN_00626	525309.HMPREF0494_0002	2.73e-35	-	-	-	-	-	-	-	-
HKDIFGKN_00627	1423807.BACO01000083_gene2425	1.03e-55	-	-	-	-	-	-	-	-
HKDIFGKN_00628	1122149.BACN01000095_gene1995	8.3e-71	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKDIFGKN_00629	1423816.BACQ01000069_gene2568	4.49e-74	-	-	-	L	-	-	-	Transposase DDE domain
HKDIFGKN_00630	511437.Lbuc_1192	5.98e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HKDIFGKN_00631	1423816.BACQ01000033_gene1383	1.53e-26	-	-	-	-	-	-	-	-
HKDIFGKN_00632	1133569.AHYZ01000098_gene924	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDIFGKN_00633	1449063.JMLS01000005_gene3200	2.09e-64	-	-	-	E	ko:K14591	-	ko00000	AroM protein
HKDIFGKN_00634	1449063.JMLS01000002_gene1237	3.43e-220	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HKDIFGKN_00635	1122921.KB898190_gene1468	9.3e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
HKDIFGKN_00636	1211035.CD30_10490	3.71e-19	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
HKDIFGKN_00637	1114972.AUAW01000027_gene721	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HKDIFGKN_00639	220668.lp_1642	3.2e-70	-	-	-	-	-	-	-	-
HKDIFGKN_00640	220668.lp_1640	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKDIFGKN_00641	220668.lp_1639	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKDIFGKN_00642	220668.lp_1638	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKDIFGKN_00643	220668.lp_1637	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKDIFGKN_00644	1136177.KCA1_1400	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKDIFGKN_00645	220668.lp_1635	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKDIFGKN_00646	220668.lp_1634	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKDIFGKN_00647	220668.lp_1633	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKDIFGKN_00648	220668.lp_1632	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKDIFGKN_00649	220668.lp_1631	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKDIFGKN_00650	220668.lp_1629	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKDIFGKN_00651	220668.lp_1628	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKDIFGKN_00652	220668.lp_1627	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKDIFGKN_00653	220668.lp_1626	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HKDIFGKN_00654	1136177.KCA1_1390	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKDIFGKN_00655	1136177.KCA1_1389	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKDIFGKN_00656	220668.lp_1622	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKDIFGKN_00657	220668.lp_1621	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKDIFGKN_00658	220668.lp_1620	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKDIFGKN_00659	220668.lp_1619	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKDIFGKN_00660	220668.lp_1618	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKDIFGKN_00661	220668.lp_1617	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKDIFGKN_00662	220668.lp_1616	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKDIFGKN_00663	220668.lp_1615	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKDIFGKN_00664	220668.lp_1614	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKDIFGKN_00665	220668.lp_1613	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKDIFGKN_00666	220668.lp_1612	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKDIFGKN_00667	220668.lp_1611	8.28e-73	-	-	-	-	-	-	-	-
HKDIFGKN_00668	220668.lp_1610	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDIFGKN_00669	220668.lp_1609	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKDIFGKN_00670	220668.lp_1608	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_00671	220668.lp_1607	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_00672	220668.lp_1605	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKDIFGKN_00673	220668.lp_1604	2.15e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKDIFGKN_00674	220668.lp_1603	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKDIFGKN_00675	220668.lp_1602	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKDIFGKN_00676	220668.lp_1601	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKDIFGKN_00677	220668.lp_1600	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKDIFGKN_00678	220668.lp_1599	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKDIFGKN_00679	220668.lp_1598	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKDIFGKN_00680	220668.lp_1597	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HKDIFGKN_00681	220668.lp_1596	4.11e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKDIFGKN_00682	220668.lp_1595	3.49e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKDIFGKN_00683	1136177.KCA1_1359	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKDIFGKN_00684	220668.lp_1593	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HKDIFGKN_00685	220668.lp_1592	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKDIFGKN_00686	220668.lp_1591	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_00687	1136177.KCA1_1355	9.81e-27	-	-	-	-	-	-	-	-
HKDIFGKN_00690	220668.lp_1587	2.97e-41	-	-	-	-	-	-	-	-
HKDIFGKN_00691	220668.lp_1586	3.11e-73	-	-	-	-	-	-	-	-
HKDIFGKN_00692	220668.lp_1585	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HKDIFGKN_00693	220668.lp_1584	2.7e-232	-	-	-	-	-	-	-	-
HKDIFGKN_00694	220668.lp_1583	1.77e-205	-	-	-	-	-	-	-	-
HKDIFGKN_00695	220668.lp_1581	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKDIFGKN_00696	220668.lp_1580	2.24e-84	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HKDIFGKN_00697	220668.lp_1579	1.55e-223	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKDIFGKN_00698	220668.lp_1578	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HKDIFGKN_00699	220668.lp_1577	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HKDIFGKN_00700	220668.lp_1576	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HKDIFGKN_00701	220668.lp_1574	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HKDIFGKN_00702	220668.lp_1573	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HKDIFGKN_00703	220668.lp_1572	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HKDIFGKN_00704	220668.lp_1571	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HKDIFGKN_00705	220668.lp_1570	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKDIFGKN_00706	1136177.KCA1_1336	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKDIFGKN_00707	220668.lp_1568	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKDIFGKN_00708	220668.lp_1567	0.0	-	-	-	S	-	-	-	membrane
HKDIFGKN_00709	220668.lp_1566	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HKDIFGKN_00710	220668.lp_1565	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKDIFGKN_00711	220668.lp_1564	9.72e-146	-	-	-	S	-	-	-	membrane
HKDIFGKN_00712	220668.lp_1563	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKDIFGKN_00713	220668.lp_1562	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HKDIFGKN_00714	220668.lp_1561	5.01e-248	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKDIFGKN_00715	220668.lp_1559	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKDIFGKN_00716	220668.lp_1558	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKDIFGKN_00717	1136177.KCA1_1325	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKDIFGKN_00718	220668.lp_1556	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKDIFGKN_00719	220668.lp_1555	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKDIFGKN_00720	1136177.KCA1_1322	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKDIFGKN_00721	220668.lp_1553	6.94e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKDIFGKN_00722	220668.lp_1552	4.18e-121	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKDIFGKN_00723	220668.lp_1549	1.36e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKDIFGKN_00724	220668.lp_1548	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HKDIFGKN_00725	220668.lp_1546	1.12e-217	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKDIFGKN_00726	220668.lp_1545	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKDIFGKN_00727	1136177.KCA1_1314	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HKDIFGKN_00728	220668.lp_1543	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKDIFGKN_00729	220668.lp_1541	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKDIFGKN_00730	220668.lp_1540	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKDIFGKN_00731	220668.lp_1539	3.57e-123	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKDIFGKN_00732	220668.lp_1535	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKDIFGKN_00733	220668.lp_1534	6.14e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKDIFGKN_00734	220668.lp_1533	9.45e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HKDIFGKN_00735	220668.lp_1532	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKDIFGKN_00736	220668.lp_1531	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HKDIFGKN_00737	220668.lp_1530	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKDIFGKN_00738	220668.lp_1529	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HKDIFGKN_00739	220668.lp_1528	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HKDIFGKN_00740	220668.lp_1527	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HKDIFGKN_00741	220668.lp_1525	6.32e-114	-	-	-	-	-	-	-	-
HKDIFGKN_00742	220668.lp_1524	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HKDIFGKN_00743	220668.lp_1523	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HKDIFGKN_00744	220668.lp_1522	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKDIFGKN_00745	220668.lp_1521	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKDIFGKN_00746	220668.lp_1519	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HKDIFGKN_00747	220668.lp_1518	4.59e-73	-	-	-	-	-	-	-	-
HKDIFGKN_00748	220668.lp_1517	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKDIFGKN_00749	1136177.KCA1_1289	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKDIFGKN_00750	220668.lp_1515	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKDIFGKN_00751	220668.lp_1514	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKDIFGKN_00752	220668.lp_1513	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKDIFGKN_00753	220668.lp_1512	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HKDIFGKN_00754	220668.lp_1511	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKDIFGKN_00755	220668.lp_1510	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKDIFGKN_00756	220668.lp_1509	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKDIFGKN_00757	220668.lp_1508	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKDIFGKN_00758	220668.lp_1507	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKDIFGKN_00759	1136177.KCA1_1260	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKDIFGKN_00760	60520.HR47_04600	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKDIFGKN_00761	220668.lp_1472	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HKDIFGKN_00762	220668.lp_1471	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKDIFGKN_00763	220668.lp_1470	4.5e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKDIFGKN_00764	60520.HR47_04540	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HKDIFGKN_00765	220668.lp_1468	2.58e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKDIFGKN_00766	220668.lp_1467	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HKDIFGKN_00767	220668.lp_1466	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKDIFGKN_00768	220668.lp_1465	4.32e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HKDIFGKN_00769	220668.lp_1462	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKDIFGKN_00770	220668.lp_1461	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKDIFGKN_00771	220668.lp_1460	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKDIFGKN_00772	220668.lp_1459	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKDIFGKN_00773	220668.lp_1458	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKDIFGKN_00774	220668.lp_1457	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HKDIFGKN_00775	220668.lp_1456	4.72e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_00776	220668.lp_1455	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_00777	220668.lp_1454	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HKDIFGKN_00778	220668.lp_1453	6.76e-73	-	-	-	-	-	-	-	-
HKDIFGKN_00779	220668.lp_1452	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKDIFGKN_00780	1136177.KCA1_1228	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HKDIFGKN_00781	220668.lp_1450	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_00782	220668.lp_1449	1.63e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_00783	220668.lp_1448	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
HKDIFGKN_00784	220668.lp_1447	1.65e-80	-	-	-	-	-	-	-	-
HKDIFGKN_00785	220668.lp_1446	5.12e-71	-	-	-	-	-	-	-	-
HKDIFGKN_00786	220668.lp_1446	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_00787	220668.lp_1445	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKDIFGKN_00788	220668.lp_1443	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_00789	220668.lp_1442	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HKDIFGKN_00790	220668.lp_1440	1.96e-137	-	-	-	-	-	-	-	-
HKDIFGKN_00791	220668.lp_1439	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HKDIFGKN_00792	220668.lp_1438	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKDIFGKN_00793	220668.lp_1437	5.12e-285	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HKDIFGKN_00794	60520.HR47_04360	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HKDIFGKN_00795	60520.HR47_04355	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKDIFGKN_00796	220668.lp_1435	0.0	-	-	-	S	-	-	-	membrane
HKDIFGKN_00797	220668.lp_1433	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HKDIFGKN_00798	220668.lp_1431	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKDIFGKN_00799	220668.lp_1431	7.78e-20	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKDIFGKN_00800	220668.lp_1430	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HKDIFGKN_00801	220668.lp_1427	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HKDIFGKN_00802	220668.lp_1426	2.57e-128	-	-	-	-	-	-	-	-
HKDIFGKN_00803	220668.lp_1425	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKDIFGKN_00804	220668.lp_1424	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKDIFGKN_00805	220668.lp_1422	1.28e-224	-	-	-	K	-	-	-	LysR substrate binding domain
HKDIFGKN_00806	220668.lp_1420	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
HKDIFGKN_00807	220668.lp_1419	8.64e-272	-	-	-	-	-	-	-	-
HKDIFGKN_00808	220668.lp_1418	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKDIFGKN_00809	220668.lp_1417	0.0	yhaN	-	-	L	-	-	-	AAA domain
HKDIFGKN_00810	220668.lp_1416	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HKDIFGKN_00811	60520.HR47_02660	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HKDIFGKN_00812	220668.lp_1413	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKDIFGKN_00813	220668.lp_1412	2.43e-18	-	-	-	-	-	-	-	-
HKDIFGKN_00814	220668.lp_1411	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKDIFGKN_00815	220668.lp_1410	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
HKDIFGKN_00816	220668.lp_1409	6.64e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HKDIFGKN_00817	220668.lp_1407	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HKDIFGKN_00818	220668.lp_1406	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKDIFGKN_00819	220668.lp_1403	1.16e-146	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKDIFGKN_00820	220668.lp_1402	4.97e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HKDIFGKN_00821	220668.lp_1401	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_00822	220668.lp_1400	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_00823	220668.lp_1399	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKDIFGKN_00824	220668.lp_1398	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKDIFGKN_00825	220668.lp_1397	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKDIFGKN_00826	220668.lp_1396	0.0	celR	-	-	K	-	-	-	PRD domain
HKDIFGKN_00827	60520.HR47_02745	1.79e-137	-	-	-	-	-	-	-	-
HKDIFGKN_00828	220668.lp_1393	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKDIFGKN_00829	220668.lp_1392	4.64e-106	-	-	-	-	-	-	-	-
HKDIFGKN_00830	220668.lp_1391	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKDIFGKN_00831	220668.lp_1390	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HKDIFGKN_00834	1400520.LFAB_08900	1.79e-42	-	-	-	-	-	-	-	-
HKDIFGKN_00835	220668.lp_1386	4.49e-316	dinF	-	-	V	-	-	-	MatE
HKDIFGKN_00836	220668.lp_1385	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HKDIFGKN_00837	220668.lp_1381	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HKDIFGKN_00838	220668.lp_1380	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HKDIFGKN_00839	220668.lp_1379	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HKDIFGKN_00840	220668.lp_1378	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HKDIFGKN_00841	220668.lp_1377	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HKDIFGKN_00842	220668.lp_1375	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKDIFGKN_00843	220668.lp_1374	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKDIFGKN_00844	220668.lp_1373	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HKDIFGKN_00845	220668.lp_1372	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKDIFGKN_00846	220668.lp_1371	1.58e-236	-	-	-	-	-	-	-	-
HKDIFGKN_00847	220668.lp_1370	9.03e-16	-	-	-	-	-	-	-	-
HKDIFGKN_00848	220668.lp_1369	4.29e-87	-	-	-	-	-	-	-	-
HKDIFGKN_00851	220668.lp_1364	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HKDIFGKN_00852	220668.lp_1363	7.12e-62	-	-	-	-	-	-	-	-
HKDIFGKN_00853	220668.lp_1362	8.82e-119	-	-	-	-	-	-	-	-
HKDIFGKN_00854	220668.lp_1360	2.58e-110	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HKDIFGKN_00855	220668.lp_1359	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_00856	220668.lp_1358	4.56e-78	-	-	-	-	-	-	-	-
HKDIFGKN_00857	220668.lp_1357	3.11e-73	-	-	-	-	-	-	-	-
HKDIFGKN_00858	220668.lp_1356	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKDIFGKN_00859	220668.lp_1355	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKDIFGKN_00860	220668.lp_1354	7.83e-140	-	-	-	-	-	-	-	-
HKDIFGKN_00861	220668.lp_1353	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKDIFGKN_00862	220668.lp_1343	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKDIFGKN_00863	220668.lp_1342	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HKDIFGKN_00864	220668.lp_1341	4.72e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDIFGKN_00865	220668.lp_1339	1.34e-32	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKDIFGKN_00866	220668.lp_1339	1.09e-151	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKDIFGKN_00868	220668.lp_1336	2.11e-225	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HKDIFGKN_00869	220668.lp_1335	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_00870	220668.lp_1334	1.16e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HKDIFGKN_00872	220668.lp_1332	1.06e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HKDIFGKN_00873	220668.lp_1330	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKDIFGKN_00874	220668.lp_1329	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKDIFGKN_00875	220668.lp_1328	2.22e-161	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKDIFGKN_00876	220668.lp_1327	9.24e-317	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKDIFGKN_00877	220668.lp_1326	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_00878	220668.lp_1325	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDIFGKN_00879	220668.lp_1324	2.92e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HKDIFGKN_00880	220668.lp_1322	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKDIFGKN_00881	220668.lp_1321	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HKDIFGKN_00882	220668.lp_1320	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKDIFGKN_00883	220668.lp_1319	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKDIFGKN_00884	220668.lp_1317	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKDIFGKN_00885	220668.lp_1316	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKDIFGKN_00886	220668.lp_1315	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HKDIFGKN_00887	220668.lp_1314	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HKDIFGKN_00888	220668.lp_1313	9.32e-40	-	-	-	-	-	-	-	-
HKDIFGKN_00889	220668.lp_1312	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKDIFGKN_00890	220668.lp_1311	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKDIFGKN_00891	220668.lp_1310	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HKDIFGKN_00892	220668.lp_1303a	2.07e-297	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HKDIFGKN_00894	220668.lp_1303a	3.8e-27	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HKDIFGKN_00895	220668.lp_1302	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_00896	220668.lp_1301	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKDIFGKN_00897	220668.lp_1300	3.35e-157	-	-	-	-	-	-	-	-
HKDIFGKN_00898	220668.lp_1299	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKDIFGKN_00899	220668.lp_1298	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HKDIFGKN_00900	220668.lp_1297	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKDIFGKN_00901	220668.lp_1296	3.59e-240	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HKDIFGKN_00902	220668.lp_1295	2.19e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKDIFGKN_00904	220668.lp_1293	4.01e-198	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKDIFGKN_00905	220668.lp_1292	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDIFGKN_00906	220668.lp_1291	1.25e-124	-	-	-	-	-	-	-	-
HKDIFGKN_00907	220668.lp_1290	5.46e-238	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HKDIFGKN_00908	220668.lp_1289	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HKDIFGKN_00919	220668.lp_0215	1.36e-62	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HKDIFGKN_00920	220668.lp_0217	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKDIFGKN_00921	220668.lp_0218	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKDIFGKN_00922	220668.lp_0219	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDIFGKN_00923	220668.lp_0220	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HKDIFGKN_00924	220668.lp_0221	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HKDIFGKN_00925	220668.lp_0223	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKDIFGKN_00926	220668.lp_0224	1.2e-91	-	-	-	-	-	-	-	-
HKDIFGKN_00927	220668.lp_0225	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HKDIFGKN_00928	220668.lp_0226	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKDIFGKN_00929	1400520.LFAB_16345	1.82e-220	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKDIFGKN_00930	1400520.LFAB_16350	5.81e-245	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HKDIFGKN_00931	1400520.LFAB_16350	1.04e-05	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HKDIFGKN_00932	1400520.LFAB_16355	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_00933	220668.lp_0228	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDIFGKN_00934	220668.lp_0230	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKDIFGKN_00935	220668.lp_0231	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HKDIFGKN_00936	220668.lp_0232	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_00937	220668.lp_0233	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HKDIFGKN_00938	220668.lp_0235	1.21e-111	-	-	-	-	-	-	-	-
HKDIFGKN_00939	220668.lp_0236	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKDIFGKN_00940	220668.lp_0237	5.92e-67	-	-	-	-	-	-	-	-
HKDIFGKN_00941	220668.lp_0239	8.27e-124	-	-	-	-	-	-	-	-
HKDIFGKN_00942	220668.lp_0240	1.73e-89	-	-	-	-	-	-	-	-
HKDIFGKN_00943	220668.lp_0242	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HKDIFGKN_00944	220668.lp_0243	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HKDIFGKN_00945	220668.lp_0244	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HKDIFGKN_00946	220668.lp_0254	7.42e-125	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HKDIFGKN_00947	220668.lp_0255	8.21e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKDIFGKN_00948	220668.lp_0256	2.52e-209	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKDIFGKN_00949	220668.lp_0257	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HKDIFGKN_00950	220668.lp_0259	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKDIFGKN_00951	220668.lp_0260	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HKDIFGKN_00952	220668.lp_0261	6.35e-56	-	-	-	-	-	-	-	-
HKDIFGKN_00953	220668.lp_0262	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKDIFGKN_00954	220668.lp_0263	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKDIFGKN_00955	220668.lp_0264	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDIFGKN_00956	220668.lp_0265	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKDIFGKN_00957	220668.lp_0266	2.6e-185	-	-	-	-	-	-	-	-
HKDIFGKN_00958	220668.lp_0267	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKDIFGKN_00959	220668.lp_0268	5.71e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HKDIFGKN_00960	220668.lp_0269	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKDIFGKN_00961	220668.lp_0271	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKDIFGKN_00962	220668.lp_0272	2.73e-92	-	-	-	-	-	-	-	-
HKDIFGKN_00963	220668.lp_0273	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_00964	220668.lp_0274	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_00965	220668.lp_0275	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKDIFGKN_00966	220668.lp_0276	4.5e-150	-	-	-	-	-	-	-	-
HKDIFGKN_00967	220668.lp_0277	6.37e-52	-	-	-	-	-	-	-	-
HKDIFGKN_00968	1136177.KCA1_0250	3.13e-55	-	-	-	-	-	-	-	-
HKDIFGKN_00969	220668.lp_0280	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_00970	220668.lp_0281	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDIFGKN_00971	220668.lp_0282	2.72e-316	hpk2	-	-	T	-	-	-	Histidine kinase
HKDIFGKN_00972	220668.lp_0283	2.58e-163	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HKDIFGKN_00973	220668.lp_0284	1.15e-63	-	-	-	-	-	-	-	-
HKDIFGKN_00974	220668.lp_0285	2.78e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKDIFGKN_00975	220668.lp_0286	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_00976	220668.lp_0287	1.94e-74	-	-	-	-	-	-	-	-
HKDIFGKN_00977	220668.lp_0289	2.87e-56	-	-	-	-	-	-	-	-
HKDIFGKN_00978	220668.lp_0290	5.06e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKDIFGKN_00979	220668.lp_0291	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HKDIFGKN_00980	220668.lp_0292	1.49e-63	-	-	-	-	-	-	-	-
HKDIFGKN_00981	220668.lp_0293	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKDIFGKN_00982	220668.lp_0294	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HKDIFGKN_00983	60520.HR47_03545	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKDIFGKN_00984	220668.lp_0296	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKDIFGKN_00985	220668.lp_0297	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKDIFGKN_00986	220668.lp_0298	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKDIFGKN_00987	220668.lp_0299	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_00988	220668.lp_0300	1.54e-169	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_00989	220668.lp_0301	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_00990	525309.HMPREF0494_2051	7.1e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKDIFGKN_00991	1133569.AHYZ01000024_gene413	8.58e-71	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKDIFGKN_00992	420890.LCGL_1906	1.06e-05	-	-	-	-	-	-	-	-
HKDIFGKN_00993	60520.HR47_03410	4.26e-37	-	-	-	-	-	-	-	-
HKDIFGKN_00994	60520.HR47_03405	9.55e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HKDIFGKN_00995	387344.LVIS_A11	2.39e-178	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_00997	60520.HR47_09180	9.48e-36	-	-	-	-	-	-	-	-
HKDIFGKN_01000	1123306.KB904350_gene1227	4.21e-58	repB	-	-	L	-	-	-	Initiator Replication protein
HKDIFGKN_01001	1423807.BACO01000056_gene1645	4.08e-25	-	-	-	-	-	-	-	-
HKDIFGKN_01002	1400520.LFAB_17305	4.71e-78	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKDIFGKN_01003	1158601.I585_04014	7.74e-102	-	-	-	L	-	-	-	Integrase core domain
HKDIFGKN_01004	1329250.WOSG25_300030	3.82e-42	-	-	-	L	-	-	-	Transposase and inactivated derivatives
HKDIFGKN_01005	218493.SBG_3301	9.32e-54	rfaB	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyltransferase Family 4
HKDIFGKN_01006	1605.Lani381_0048	6.19e-30	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKDIFGKN_01007	1121105.ATXL01000025_gene2074	4.22e-28	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HKDIFGKN_01008	866895.HBHAL_1978	2.33e-74	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKDIFGKN_01011	1231377.C426_1826	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HKDIFGKN_01013	1045004.OKIT_0519	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HKDIFGKN_01014	1423780.LOT_2224	3.33e-107	-	-	-	-	-	-	-	-
HKDIFGKN_01015	1423807.BACO01000083_gene2425	5.98e-55	-	-	-	-	-	-	-	-
HKDIFGKN_01016	1423734.JCM14202_2802	1.69e-37	-	-	-	-	-	-	-	-
HKDIFGKN_01017	1423780.LOT_2221	0.0	-	-	-	L	-	-	-	MobA MobL family protein
HKDIFGKN_01018	525309.HMPREF0494_0082	8.84e-210	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKDIFGKN_01019	913848.AELK01000080_gene1673	2.32e-81	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKDIFGKN_01020	525309.HMPREF0494_0081	1.4e-133	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKDIFGKN_01021	525309.HMPREF0494_0080	7.9e-108	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKDIFGKN_01022	1400520.LFAB_06340	2.1e-17	-	-	-	-	-	-	-	-
HKDIFGKN_01023	1400520.LFAB_15450	4.13e-28	-	-	-	S	-	-	-	Mor transcription activator family
HKDIFGKN_01026	387344.LVIS_1815	1.27e-92	-	-	-	S	-	-	-	Protease prsW family
HKDIFGKN_01027	1423734.JCM14202_4064	1.52e-104	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKDIFGKN_01028	60520.HR47_01785	1.68e-15	-	-	-	-	-	-	-	-
HKDIFGKN_01030	1400520.LFAB_15440	9.74e-101	-	-	-	-	-	-	-	-
HKDIFGKN_01031	220668.lp_0988	2.14e-58	-	-	-	-	-	-	-	-
HKDIFGKN_01033	1267003.KB911387_gene1883	2.09e-171	int3	-	-	L	-	-	-	Phage integrase SAM-like domain
HKDIFGKN_01034	1138822.PL11_10125	6.01e-314	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HKDIFGKN_01035	220668.lp_3170	3.89e-41	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKDIFGKN_01036	220668.lp_3169	6.79e-53	-	-	-	-	-	-	-	-
HKDIFGKN_01037	1114972.AUAW01000022_gene1267	8.53e-111	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01038	1114972.AUAW01000022_gene1268	6.96e-71	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKDIFGKN_01039	1114972.AUAW01000022_gene1269	1.92e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKDIFGKN_01040	1114972.AUAW01000022_gene1270	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_01041	220668.lp_3150	2.23e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HKDIFGKN_01042	1423816.BACQ01000047_gene1756	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_01043	1400520.LFAB_05710	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_01044	1423816.BACQ01000047_gene1754	5.36e-76	-	-	-	-	-	-	-	-
HKDIFGKN_01045	220668.lp_3143	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKDIFGKN_01046	220668.lp_3142	1.83e-122	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HKDIFGKN_01047	220668.lp_3141	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HKDIFGKN_01048	220668.lp_3139	2.23e-279	-	-	-	S	-	-	-	Membrane
HKDIFGKN_01049	220668.lp_3134	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKDIFGKN_01050	1545701.LACWKB10_1045	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDIFGKN_01051	1423734.JCM14202_437	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKDIFGKN_01052	220668.lp_3129	1.8e-16	-	-	-	-	-	-	-	-
HKDIFGKN_01053	1136177.KCA1_2566	2.09e-85	-	-	-	-	-	-	-	-
HKDIFGKN_01054	1136177.KCA1_2565	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_01055	1136177.KCA1_2564	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_01056	1136177.KCA1_2563	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HKDIFGKN_01057	1074451.CRL705_1934	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKDIFGKN_01058	220668.lp_3127	0.0	-	-	-	S	-	-	-	MucBP domain
HKDIFGKN_01059	220668.lp_3125	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKDIFGKN_01060	220668.lp_3124	1.76e-204	-	-	-	K	-	-	-	LysR substrate binding domain
HKDIFGKN_01061	220668.lp_3123	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HKDIFGKN_01062	220668.lp_3122	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKDIFGKN_01063	220668.lp_3120	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKDIFGKN_01064	220668.lp_3119	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_01065	220668.lp_3117	1.6e-261	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HKDIFGKN_01066	220668.lp_3116	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_01067	220668.lp_3115	1.12e-229	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKDIFGKN_01068	220668.lp_3114	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKDIFGKN_01069	220668.lp_3113	4.51e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDIFGKN_01070	220668.lp_3112	4.95e-152	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKDIFGKN_01071	220668.lp_3112	4.18e-17	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKDIFGKN_01072	220668.lp_3111	8.08e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HKDIFGKN_01073	220668.lp_3110	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKDIFGKN_01074	220668.lp_3108	5.53e-210	-	-	-	GM	-	-	-	NmrA-like family
HKDIFGKN_01075	220668.lp_3107	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_01076	220668.lp_3106	1.16e-219	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKDIFGKN_01077	220668.lp_3105	3.69e-176	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKDIFGKN_01078	220668.lp_3105	2.85e-23	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKDIFGKN_01079	220668.lp_3104	8.69e-186	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKDIFGKN_01080	220668.lp_3103	1.73e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HKDIFGKN_01081	220668.lp_3102	2.64e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_01082	220668.lp_3101	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HKDIFGKN_01084	220668.lp_3100	3.27e-228	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKDIFGKN_01085	220668.lp_3099	1.27e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKDIFGKN_01086	220668.lp_3098	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HKDIFGKN_01087	220668.lp_3097	7.57e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_01088	220668.lp_3096	2.69e-169	-	-	-	S	-	-	-	KR domain
HKDIFGKN_01089	220668.lp_3095	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKDIFGKN_01090	220668.lp_3094	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HKDIFGKN_01091	220668.lp_3093	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKDIFGKN_01092	220668.lp_3092	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKDIFGKN_01093	220668.lp_3091	2.09e-213	-	-	-	GM	-	-	-	NmrA-like family
HKDIFGKN_01094	220668.lp_3090	1.15e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_01095	220668.lp_3088	5.93e-281	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKDIFGKN_01096	220668.lp_3087	8.01e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKDIFGKN_01097	220668.lp_3085	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKDIFGKN_01098	220668.lp_3084	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKDIFGKN_01099	220668.lp_3082	5.78e-269	-	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_01100	220668.lp_3081	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKDIFGKN_01101	220668.lp_3078	1.06e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKDIFGKN_01102	220668.lp_3077	9.69e-156	-	-	-	-	-	-	-	-
HKDIFGKN_01103	220668.lp_3075	2.11e-300	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HKDIFGKN_01104	220668.lp_3074	1.21e-82	-	-	-	-	-	-	-	-
HKDIFGKN_01105	220668.lp_3073	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_01106	220668.lp_3072	3.74e-242	ynjC	-	-	S	-	-	-	Cell surface protein
HKDIFGKN_01107	220668.lp_3071	2.63e-146	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HKDIFGKN_01108	220668.lp_3070	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKDIFGKN_01109	220668.lp_3069	6.57e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HKDIFGKN_01110	60520.HR47_04215	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_01111	220668.lp_3066	7.81e-241	-	-	-	S	-	-	-	Cell surface protein
HKDIFGKN_01112	220668.lp_3065	2.69e-99	-	-	-	-	-	-	-	-
HKDIFGKN_01113	220668.lp_3064	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_01114	220668.lp_3063	6.16e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKDIFGKN_01115	220668.lp_3062	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HKDIFGKN_01116	220668.lp_3060	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_01117	220668.lp_3059	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKDIFGKN_01118	220668.lp_3058	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HKDIFGKN_01119	220668.lp_3057	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HKDIFGKN_01120	220668.lp_3055	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKDIFGKN_01121	220668.lp_3054	3.93e-271	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HKDIFGKN_01122	220668.lp_3051	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HKDIFGKN_01123	220668.lp_3050	4.8e-86	lysM	-	-	M	-	-	-	LysM domain
HKDIFGKN_01124	220668.lp_3049	0.0	-	-	-	E	-	-	-	Amino Acid
HKDIFGKN_01125	220668.lp_3048	1.43e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKDIFGKN_01126	220668.lp_3047	1.97e-92	-	-	-	-	-	-	-	-
HKDIFGKN_01128	220668.lp_3045	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
HKDIFGKN_01129	220668.lp_3044	3.23e-290	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HKDIFGKN_01131	220668.lp_3042	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01132	220668.lp_3040	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_01133	220668.lp_3038	2.31e-277	-	-	-	-	-	-	-	-
HKDIFGKN_01134	220668.lp_3023	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HKDIFGKN_01135	220668.lp_3022	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKDIFGKN_01136	220668.lp_3021	1.73e-254	-	-	-	T	-	-	-	diguanylate cyclase
HKDIFGKN_01137	220668.lp_3020	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HKDIFGKN_01138	220668.lp_3019	3.57e-120	-	-	-	-	-	-	-	-
HKDIFGKN_01139	220668.lp_3018	9.56e-211	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKDIFGKN_01140	220668.lp_3017	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HKDIFGKN_01141	220668.lp_3016	8.11e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKDIFGKN_01142	220668.lp_3015	7.94e-126	-	-	-	M	-	-	-	Lysin motif
HKDIFGKN_01143	220668.lp_3014	4.61e-101	-	-	-	M	-	-	-	LysM domain
HKDIFGKN_01144	220668.lp_3013	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDIFGKN_01145	220668.lp_3012	1.25e-26	-	-	-	GM	-	-	-	Male sterility protein
HKDIFGKN_01146	220668.lp_3012	7.21e-183	-	-	-	GM	-	-	-	Male sterility protein
HKDIFGKN_01147	220668.lp_3011	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_01148	220668.lp_3010	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_01149	220668.lp_3009	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKDIFGKN_01150	220668.lp_3008	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKDIFGKN_01151	220668.lp_3006	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_01152	220668.lp_3004	1.21e-73	-	-	-	-	-	-	-	-
HKDIFGKN_01153	220668.lp_3003	1.58e-204	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKDIFGKN_01154	220668.lp_3002	2.03e-84	-	-	-	-	-	-	-	-
HKDIFGKN_01155	220668.lp_3001	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HKDIFGKN_01156	220668.lp_3000	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01157	220668.lp_2998	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HKDIFGKN_01158	60520.HR47_01805	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HKDIFGKN_01159	220668.lp_2995	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKDIFGKN_01160	220668.lp_2994	7.03e-62	-	-	-	-	-	-	-	-
HKDIFGKN_01161	220668.lp_2993	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKDIFGKN_01162	220668.lp_2992	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKDIFGKN_01163	220668.lp_2991	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKDIFGKN_01164	220668.lp_2989	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HKDIFGKN_01165	220668.lp_2988	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKDIFGKN_01166	220668.lp_2987	1.15e-43	-	-	-	-	-	-	-	-
HKDIFGKN_01168	220668.lp_2985	2.98e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKDIFGKN_01169	220668.lp_2984	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKDIFGKN_01170	220668.lp_2983	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKDIFGKN_01171	220668.lp_2982	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HKDIFGKN_01172	220668.lp_2981	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_01173	220668.lp_2980	3.13e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HKDIFGKN_01174	220668.lp_2979	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HKDIFGKN_01175	220668.lp_2978	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_01176	220668.lp_2977	9.55e-243	-	-	-	S	-	-	-	Cell surface protein
HKDIFGKN_01177	220668.lp_2976	4.71e-81	-	-	-	-	-	-	-	-
HKDIFGKN_01178	220668.lp_2975	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_01179	220668.lp_2974	6.97e-216	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_01180	220668.lp_2973	2.48e-199	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKDIFGKN_01181	220668.lp_2972	2.43e-149	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKDIFGKN_01182	220668.lp_2969	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKDIFGKN_01183	220668.lp_2968	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HKDIFGKN_01184	60520.HR47_01930	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKDIFGKN_01185	60520.HR47_01935	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
HKDIFGKN_01186	60520.HR47_01940	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKDIFGKN_01187	220668.lp_2966	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HKDIFGKN_01188	60520.HR47_01950	9.86e-117	-	-	-	-	-	-	-	-
HKDIFGKN_01189	60520.HR47_01955	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HKDIFGKN_01190	220668.lp_2965	3.57e-205	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKDIFGKN_01191	220668.lp_2964	5.07e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKDIFGKN_01192	220668.lp_2963	5.93e-144	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HKDIFGKN_01193	220668.lp_2961	3.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HKDIFGKN_01194	220668.lp_2960	5.03e-165	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKDIFGKN_01195	220668.lp_2959	9.84e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
HKDIFGKN_01196	220668.lp_2958	6e-299	-	-	-	M	-	-	-	Collagen binding domain
HKDIFGKN_01197	220668.lp_2956	0.0	-	-	-	I	-	-	-	acetylesterase activity
HKDIFGKN_01198	220668.lp_2954	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HKDIFGKN_01199	220668.lp_2953	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HKDIFGKN_01200	220668.lp_2952	4.29e-50	-	-	-	-	-	-	-	-
HKDIFGKN_01202	220668.lp_2949	9.23e-181	-	-	-	S	-	-	-	zinc-ribbon domain
HKDIFGKN_01203	220668.lp_2948	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HKDIFGKN_01204	220668.lp_2945	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HKDIFGKN_01205	220668.lp_2943	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HKDIFGKN_01206	220668.lp_2942	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HKDIFGKN_01207	220668.lp_2940	1.38e-131	-	-	-	-	-	-	-	-
HKDIFGKN_01208	220668.lp_2939	3.7e-30	-	-	-	-	-	-	-	-
HKDIFGKN_01209	220668.lp_2937	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKDIFGKN_01210	220668.lp_2936	1.07e-241	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKDIFGKN_01211	220668.lp_2935	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKDIFGKN_01212	220668.lp_2934	1.56e-108	-	-	-	-	-	-	-	-
HKDIFGKN_01213	220668.lp_2932	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HKDIFGKN_01214	220668.lp_2931	6.36e-134	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKDIFGKN_01215	220668.lp_2930	1.06e-33	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKDIFGKN_01216	220668.lp_2930	1.92e-96	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKDIFGKN_01217	220668.lp_2929	5.64e-277	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HKDIFGKN_01218	220668.lp_2927	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKDIFGKN_01219	220668.lp_2926	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HKDIFGKN_01220	220668.lp_2925	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_01221	220668.lp_2924	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKDIFGKN_01222	220668.lp_2923	9.55e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKDIFGKN_01223	220668.lp_2922	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HKDIFGKN_01224	220668.lp_2921	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HKDIFGKN_01225	220668.lp_2918	1.54e-219	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKDIFGKN_01226	220668.lp_2917	1.35e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKDIFGKN_01227	220668.lp_2915	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HKDIFGKN_01228	220668.lp_2914	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKDIFGKN_01229	220668.lp_2913	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKDIFGKN_01230	220668.lp_2912	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKDIFGKN_01231	220668.lp_2911	2.09e-287	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_01232	220668.lp_2909	3.57e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKDIFGKN_01233	220668.lp_2907	1.39e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKDIFGKN_01234	220668.lp_2906	4.36e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKDIFGKN_01235	220668.lp_2903	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDIFGKN_01236	220668.lp_2902	1.23e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HKDIFGKN_01237	60520.HR47_01460	2.06e-314	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HKDIFGKN_01241	220668.lp_2897	4.11e-232	-	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_01242	220668.lp_2896	5.78e-42	-	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_01243	220668.lp_2894	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_01244	220668.lp_2893	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_01246	220668.lp_2890	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
HKDIFGKN_01247	220668.lp_2889	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HKDIFGKN_01248	60520.HR47_00020	1.91e-282	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKDIFGKN_01249	220668.lp_2887	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKDIFGKN_01250	220668.lp_2885	2.31e-79	-	-	-	-	-	-	-	-
HKDIFGKN_01251	220668.lp_2879	1.76e-162	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKDIFGKN_01252	220668.lp_2878	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HKDIFGKN_01253	220668.lp_2877	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKDIFGKN_01254	220668.lp_2876	1.28e-45	-	-	-	-	-	-	-	-
HKDIFGKN_01255	220668.lp_2874	1.38e-192	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKDIFGKN_01256	220668.lp_2873	6.77e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKDIFGKN_01257	220668.lp_2872	8.81e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HKDIFGKN_01258	220668.lp_2871	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
HKDIFGKN_01259	220668.lp_2870	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HKDIFGKN_01260	220668.lp_2868	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HKDIFGKN_01261	220668.lp_2867	2.81e-64	-	-	-	-	-	-	-	-
HKDIFGKN_01262	220668.lp_2866	9.76e-50	-	-	-	-	-	-	-	-
HKDIFGKN_01263	220668.lp_2865	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
HKDIFGKN_01264	220668.lp_2864	4.86e-111	-	-	-	-	-	-	-	-
HKDIFGKN_01266	220668.lp_2862	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKDIFGKN_01267	220668.lp_2861	1.84e-140	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKDIFGKN_01268	60520.HR47_02190	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKDIFGKN_01270	60520.HR47_02180	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01271	220668.lp_2856	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDIFGKN_01272	220668.lp_2855	1.46e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKDIFGKN_01273	220668.lp_2854	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HKDIFGKN_01274	220668.lp_2853	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HKDIFGKN_01275	60520.HR47_02155	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKDIFGKN_01276	220668.lp_2851	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKDIFGKN_01277	220668.lp_2850	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKDIFGKN_01278	220668.lp_2849	4.06e-213	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01279	220668.lp_2848	6.5e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HKDIFGKN_01280	220668.lp_2847	2.75e-81	-	-	-	M	-	-	-	LysM domain
HKDIFGKN_01281	220668.342242703	8.43e-45	-	-	-	M	-	-	-	LysM domain protein
HKDIFGKN_01282	220668.lp_2844	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKDIFGKN_01283	220668.lp_2843	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKDIFGKN_01284	220668.lp_2842	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HKDIFGKN_01285	220668.lp_2841	1.2e-219	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKDIFGKN_01286	220668.lp_2840	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKDIFGKN_01287	220668.lp_2839	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKDIFGKN_01288	220668.lp_2836	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKDIFGKN_01289	220668.lp_2835	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKDIFGKN_01290	220668.lp_2833	4.32e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKDIFGKN_01291	220668.lp_2830	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HKDIFGKN_01292	220668.lp_2829	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKDIFGKN_01293	60520.HR47_02060	8.64e-153	-	-	-	S	-	-	-	Membrane
HKDIFGKN_01294	220668.lp_2827	9.35e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKDIFGKN_01295	220668.lp_2826	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HKDIFGKN_01296	220668.lp_2825	6.68e-237	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HKDIFGKN_01297	220668.lp_2824	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HKDIFGKN_01298	220668.lp_2823	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01299	220668.lp_2822	6.93e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDIFGKN_01300	220668.lp_2820	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HKDIFGKN_01301	220668.lp_2818	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKDIFGKN_01302	220668.lp_2817	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HKDIFGKN_01303	220668.lp_2816	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKDIFGKN_01304	220668.lp_2813	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKDIFGKN_01305	220668.lp_2812	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
HKDIFGKN_01306	220668.lp_2810	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKDIFGKN_01307	220668.lp_2809	1.27e-143	-	-	-	-	-	-	-	-
HKDIFGKN_01308	220668.lp_2807	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKDIFGKN_01309	220668.lp_2806	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HKDIFGKN_01310	220668.lp_2457	1.98e-40	-	-	-	-	-	-	-	-
HKDIFGKN_01313	220668.lp_2461	4.32e-73	-	-	-	-	-	-	-	-
HKDIFGKN_01314	60520.HR47_10390	1.62e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKDIFGKN_01317	60520.HR47_10405	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HKDIFGKN_01318	60520.HR47_10410	3.56e-259	-	-	-	S	-	-	-	Phage portal protein
HKDIFGKN_01320	1400520.LFAB_00210	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HKDIFGKN_01321	60520.HR47_10425	2.22e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HKDIFGKN_01322	1400520.LFAB_15775	7.71e-91	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
HKDIFGKN_01323	60520.HR47_10435	1.87e-65	-	-	-	S	-	-	-	Head-tail joining protein
HKDIFGKN_01325	1400520.LFAB_15680	3.36e-96	-	-	-	-	-	-	-	-
HKDIFGKN_01326	60520.HR47_10450	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HKDIFGKN_01327	60520.HR47_10455	6.03e-178	-	-	-	L	-	-	-	DNA replication protein
HKDIFGKN_01328	1400520.LFAB_10920	1.78e-38	-	-	-	-	-	-	-	-
HKDIFGKN_01329	1400520.LFAB_10925	1.62e-12	-	-	-	-	-	-	-	-
HKDIFGKN_01331	764291.STRUR_2168	4.83e-09	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HKDIFGKN_01332	1400520.LFAB_10940	1.96e-160	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKDIFGKN_01333	1400520.LFAB_10940	9.34e-86	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKDIFGKN_01334	220668.lp_2482	1.28e-51	-	-	-	-	-	-	-	-
HKDIFGKN_01335	220668.lp_2483	1.09e-56	-	-	-	-	-	-	-	-
HKDIFGKN_01336	220668.lp_2484	1.27e-109	-	-	-	K	-	-	-	MarR family
HKDIFGKN_01337	220668.lp_2485	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HKDIFGKN_01338	1136177.KCA1_2030	5.47e-200	inlJ	-	-	M	-	-	-	MucBP domain
HKDIFGKN_01339	1136177.KCA1_2030	2.63e-20	inlJ	-	-	M	-	-	-	MucBP domain
HKDIFGKN_01340	220668.lp_2488	9.05e-22	-	-	-	-	-	-	-	-
HKDIFGKN_01341	1136177.KCA1_2034	2.69e-23	-	-	-	-	-	-	-	-
HKDIFGKN_01342	220668.lp_2488c	9.85e-22	-	-	-	-	-	-	-	-
HKDIFGKN_01345	1138822.PL11_10705	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HKDIFGKN_01347	1121342.AUCO01000004_gene715	4.84e-38	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKDIFGKN_01348	1122149.BACN01000031_gene1406	8.66e-19	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKDIFGKN_01349	220668.lp_0869	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HKDIFGKN_01350	220668.lp_0871	5.86e-188	-	-	-	-	-	-	-	-
HKDIFGKN_01351	220668.lp_0872	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HKDIFGKN_01352	60520.HR47_04950	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKDIFGKN_01353	60520.HR47_04955	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKDIFGKN_01354	220668.lp_0875	1.28e-54	-	-	-	-	-	-	-	-
HKDIFGKN_01356	220668.lp_0878	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01357	220668.lp_0881	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKDIFGKN_01358	220668.lp_0882	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_01359	220668.lp_0883	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_01360	220668.lp_0884	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKDIFGKN_01361	220668.lp_0885	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKDIFGKN_01362	220668.lp_0886	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKDIFGKN_01363	220668.lp_0887	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HKDIFGKN_01364	220668.lp_0888	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HKDIFGKN_01365	220668.lp_0889	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKDIFGKN_01366	220668.lp_0891	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HKDIFGKN_01367	220668.lp_0892	8.83e-93	-	-	-	K	-	-	-	MarR family
HKDIFGKN_01368	220668.lp_0893	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKDIFGKN_01369	220668.lp_0894	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKDIFGKN_01370	220668.lp_0895	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_01371	220668.lp_0896	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKDIFGKN_01372	220668.lp_0897	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HKDIFGKN_01373	220668.lp_0898	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HKDIFGKN_01374	220668.lp_0899	1.61e-36	-	-	-	-	-	-	-	-
HKDIFGKN_01375	220668.lp_0900	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HKDIFGKN_01376	220668.lp_0901	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HKDIFGKN_01377	220668.lp_0902	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HKDIFGKN_01378	220668.lp_0903	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HKDIFGKN_01379	60520.HR47_05080	7.47e-142	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HKDIFGKN_01380	220668.lp_0910	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKDIFGKN_01381	220668.lp_0912	1.46e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HKDIFGKN_01382	220668.lp_0913	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKDIFGKN_01383	220668.lp_0914	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKDIFGKN_01385	1423734.JCM14202_2533	4.33e-226	arsB	-	-	U	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKDIFGKN_01386	220668.45723560	4.68e-43	-	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDIFGKN_01387	1133569.AHYZ01000008_gene50	1.44e-179	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKDIFGKN_01388	1122149.BACN01000100_gene1982	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
HKDIFGKN_01389	220668.lp_0304	1.37e-92	-	-	-	M	-	-	-	LysM domain protein
HKDIFGKN_01390	220668.lp_0305	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HKDIFGKN_01391	220668.lp_0306	4.29e-227	-	-	-	-	-	-	-	-
HKDIFGKN_01392	220668.lp_0307	3.27e-168	-	-	-	-	-	-	-	-
HKDIFGKN_01393	220668.lp_0308	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HKDIFGKN_01394	220668.lp_0309	3.01e-75	-	-	-	-	-	-	-	-
HKDIFGKN_01395	220668.lp_0310	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKDIFGKN_01396	220668.lp_0311	9.81e-33	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HKDIFGKN_01397	220668.lp_0312	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_01398	220668.lp_0313	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKDIFGKN_01399	220668.lp_0314	2.18e-53	-	-	-	-	-	-	-	-
HKDIFGKN_01400	220668.lp_0315	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_01401	220668.lp_0316	4.39e-178	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_01402	220668.lp_0317	6.34e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_01403	220668.lp_0318	8.8e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKDIFGKN_01404	220668.lp_0319	1.05e-124	-	-	-	K	-	-	-	Cupin domain
HKDIFGKN_01405	220668.lp_0320	8.08e-110	-	-	-	S	-	-	-	ASCH
HKDIFGKN_01406	220668.lp_0321	1.88e-111	-	-	-	K	-	-	-	GNAT family
HKDIFGKN_01407	220668.lp_0322	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
HKDIFGKN_01408	220668.lp_0324	2.06e-30	-	-	-	-	-	-	-	-
HKDIFGKN_01409	220668.lp_0325	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKDIFGKN_01410	220668.lp_0326	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_01411	220668.lp_0327	1.08e-243	-	-	-	-	-	-	-	-
HKDIFGKN_01412	220668.lp_0329	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HKDIFGKN_01413	220668.lp_0330	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HKDIFGKN_01415	220668.lp_0331	2.75e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HKDIFGKN_01416	220668.lp_0332	5.81e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HKDIFGKN_01417	220668.lp_0333	3.48e-40	-	-	-	-	-	-	-	-
HKDIFGKN_01418	220668.lp_0334	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDIFGKN_01419	220668.lp_0335	6.4e-54	-	-	-	-	-	-	-	-
HKDIFGKN_01420	220668.lp_0336	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKDIFGKN_01421	220668.lp_0337	6.8e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKDIFGKN_01422	220668.lp_0338	3.08e-81	-	-	-	S	-	-	-	CHY zinc finger
HKDIFGKN_01423	220668.lp_0339	3.51e-281	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKDIFGKN_01424	220668.lp_0340	1.57e-280	-	-	-	-	-	-	-	-
HKDIFGKN_01425	220668.lp_0343	1.15e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HKDIFGKN_01426	220668.lp_0344	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKDIFGKN_01427	220668.lp_0346	3.93e-59	-	-	-	-	-	-	-	-
HKDIFGKN_01428	220668.lp_0347	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKDIFGKN_01429	220668.lp_0348	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKDIFGKN_01430	220668.lp_0349	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HKDIFGKN_01431	220668.lp_0350	1.05e-225	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKDIFGKN_01432	220668.lp_0351	8.95e-60	-	-	-	-	-	-	-	-
HKDIFGKN_01433	220668.lp_0353	4.98e-131	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKDIFGKN_01434	220668.lp_0354	8.36e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKDIFGKN_01435	220668.lp_0355	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HKDIFGKN_01436	220668.lp_0357	7.59e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKDIFGKN_01437	220668.lp_0358	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKDIFGKN_01438	220668.lp_0359	9.31e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKDIFGKN_01439	220668.lp_0360	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HKDIFGKN_01440	220668.lp_0361	2.16e-103	-	-	-	-	-	-	-	-
HKDIFGKN_01441	220668.lp_0362	3.45e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKDIFGKN_01442	60520.HR47_09085	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HKDIFGKN_01443	60520.HR47_09080	4.01e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKDIFGKN_01444	203120.LEUM_1016	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HKDIFGKN_01445	220668.lp_0367	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKDIFGKN_01446	220668.lp_0368	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01447	220668.lp_0369	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKDIFGKN_01448	220668.lp_0370	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKDIFGKN_01449	220668.lp_0371	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HKDIFGKN_01450	220668.lp_0372	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKDIFGKN_01451	220668.lp_0373	0.0	-	-	-	M	-	-	-	domain protein
HKDIFGKN_01452	220668.lp_0374	8.91e-86	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HKDIFGKN_01453	169963.lmo0146	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
HKDIFGKN_01454	220668.lp_0379	1.23e-226	-	-	-	-	-	-	-	-
HKDIFGKN_01455	1158612.I580_02656	1.24e-11	-	-	-	S	-	-	-	Immunity protein 22
HKDIFGKN_01456	220668.lp_0381	3.41e-130	-	-	-	S	-	-	-	ankyrin repeats
HKDIFGKN_01457	1122149.BACN01000013_gene1294	5.21e-53	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKDIFGKN_01458	1423747.BAMJ01000010_gene846	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HKDIFGKN_01459	1423780.LOT_1606	6.41e-40	-	-	-	S	-	-	-	MazG-like family
HKDIFGKN_01460	1423743.JCM14108_2631	7.19e-246	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKDIFGKN_01462	1234679.BN424_100	1.44e-124	-	-	-	V	-	-	-	COG1401 GTPase subunit of restriction endonuclease
HKDIFGKN_01463	796942.HMPREF9623_01601	1.1e-24	-	-	-	-	-	-	-	-
HKDIFGKN_01464	220668.lp_3310	6.21e-124	-	-	-	V	-	-	-	VanZ like family
HKDIFGKN_01465	220668.lp_3312	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HKDIFGKN_01466	220668.lp_3313	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HKDIFGKN_01467	220668.lp_3314	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKDIFGKN_01468	220668.lp_3316	5.17e-70	-	-	-	S	-	-	-	Pfam:DUF59
HKDIFGKN_01469	220668.lp_3318	1.22e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKDIFGKN_01470	220668.lp_3319	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HKDIFGKN_01471	220668.lp_3321	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HKDIFGKN_01472	220668.lp_3322	4.29e-101	-	-	-	-	-	-	-	-
HKDIFGKN_01473	220668.lp_3323	5.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKDIFGKN_01474	220668.lp_3324	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HKDIFGKN_01475	220668.lp_3327	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HKDIFGKN_01477	220668.lp_3330	9.45e-160	-	-	-	S	-	-	-	YjbR
HKDIFGKN_01478	220668.lp_3333	4.04e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKDIFGKN_01479	220668.lp_3333	3.23e-215	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKDIFGKN_01480	220668.lp_3334	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKDIFGKN_01481	220668.lp_3335	1.44e-255	glmS2	-	-	M	-	-	-	SIS domain
HKDIFGKN_01482	60520.HR47_01360	2.07e-35	-	-	-	S	-	-	-	Belongs to the LOG family
HKDIFGKN_01483	220668.lp_3338	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKDIFGKN_01484	220668.lp_3339	9.04e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKDIFGKN_01485	220668.lp_3341	5.85e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_01486	220668.lp_3341	5.38e-92	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_01487	220668.lp_3342	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HKDIFGKN_01488	220668.lp_3343	6.47e-208	-	-	-	GM	-	-	-	NmrA-like family
HKDIFGKN_01489	220668.lp_3344	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HKDIFGKN_01490	220668.lp_3345	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HKDIFGKN_01491	220668.lp_3346	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HKDIFGKN_01492	220668.lp_3348	1.7e-70	-	-	-	-	-	-	-	-
HKDIFGKN_01493	220668.lp_3349	1.67e-273	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HKDIFGKN_01494	220668.lp_3350	2.11e-82	-	-	-	-	-	-	-	-
HKDIFGKN_01495	220668.lp_3351	3.89e-112	-	-	-	-	-	-	-	-
HKDIFGKN_01496	220668.lp_3352	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKDIFGKN_01497	220668.lp_3353	3.78e-73	-	-	-	-	-	-	-	-
HKDIFGKN_01498	1136177.KCA1_2738	4.79e-21	-	-	-	-	-	-	-	-
HKDIFGKN_01499	220668.lp_3355	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HKDIFGKN_01500	220668.lp_3356	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HKDIFGKN_01501	220668.lp_3358	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HKDIFGKN_01502	220668.lp_3359	2.66e-155	-	-	-	S	-	-	-	membrane
HKDIFGKN_01503	220668.lp_3360	1.47e-144	-	-	-	S	-	-	-	VIT family
HKDIFGKN_01504	220668.lp_3362	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HKDIFGKN_01505	220668.lp_3363	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKDIFGKN_01506	220668.lp_3365	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HKDIFGKN_01507	220668.lp_3366	4.26e-54	-	-	-	-	-	-	-	-
HKDIFGKN_01508	220668.lp_3367	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HKDIFGKN_01509	60520.HR47_01240	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HKDIFGKN_01510	220668.lp_3371	7.21e-35	-	-	-	-	-	-	-	-
HKDIFGKN_01511	220668.lp_3372	2.55e-65	-	-	-	-	-	-	-	-
HKDIFGKN_01512	220668.lp_3373	2.51e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HKDIFGKN_01513	220668.lp_3374	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HKDIFGKN_01514	220668.lp_3392	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKDIFGKN_01515	220668.lp_3393	3.46e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKDIFGKN_01516	220668.lp_3394	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HKDIFGKN_01517	60520.HR47_00245	4.66e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HKDIFGKN_01518	220668.lp_3398	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKDIFGKN_01519	220668.lp_3400	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKDIFGKN_01520	220668.lp_3402	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKDIFGKN_01521	220668.lp_3403	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HKDIFGKN_01522	220668.lp_3404	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKDIFGKN_01523	220668.lp_3405	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKDIFGKN_01524	1136177.KCA1_2769	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKDIFGKN_01525	220668.lp_3407	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKDIFGKN_01526	220668.lp_3408	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HKDIFGKN_01527	220668.lp_3409	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HKDIFGKN_01528	220668.lp_3410	1.58e-66	-	-	-	-	-	-	-	-
HKDIFGKN_01529	220668.lp_3411	9.81e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HKDIFGKN_01530	220668.lp_3412	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_01531	220668.lp_3413	7.89e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKDIFGKN_01532	220668.lp_3414	1.29e-169	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_01533	220668.lp_3415	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HKDIFGKN_01534	220668.lp_3416	3.08e-113	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKDIFGKN_01535	220668.lp_3417	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_01536	220668.lp_3418	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HKDIFGKN_01537	220668.lp_3419	4.45e-38	-	-	-	-	-	-	-	-
HKDIFGKN_01538	220668.lp_3420	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HKDIFGKN_01539	220668.lp_3421	1.88e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
HKDIFGKN_01540	220668.lp_3422	2.52e-70	-	-	-	-	-	-	-	-
HKDIFGKN_01541	220668.lp_3423	5.77e-81	-	-	-	-	-	-	-	-
HKDIFGKN_01544	220668.lp_3429	4.58e-134	-	-	-	K	-	-	-	transcriptional regulator
HKDIFGKN_01545	220668.lp_3430	4.84e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HKDIFGKN_01546	60520.HR47_00405	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKDIFGKN_01547	220668.lp_3432	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HKDIFGKN_01548	220668.lp_3433	1.39e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKDIFGKN_01549	220668.lp_3435	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HKDIFGKN_01550	220668.lp_3436	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKDIFGKN_01551	1423734.JCM14202_2812	6.7e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HKDIFGKN_01552	1423734.JCM14202_2813	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HKDIFGKN_01553	220668.lp_3440	1.01e-26	-	-	-	-	-	-	-	-
HKDIFGKN_01554	220668.lp_3441	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HKDIFGKN_01555	220668.lp_3442	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HKDIFGKN_01556	220668.lp_3444	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HKDIFGKN_01557	220668.lp_3445	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKDIFGKN_01558	220668.lp_3448	1.06e-106	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKDIFGKN_01559	220668.lp_3449	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HKDIFGKN_01560	220668.lp_3450	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKDIFGKN_01561	220668.lp_3451	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HKDIFGKN_01562	220668.lp_3452	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_01563	220668.lp_3453	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_01564	220668.lp_3454	7.83e-60	-	-	-	-	-	-	-	-
HKDIFGKN_01565	220668.lp_3458	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HKDIFGKN_01566	220668.lp_3459	1.03e-65	-	-	-	-	-	-	-	-
HKDIFGKN_01567	220668.lp_3460	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HKDIFGKN_01568	220668.lp_3461	3.17e-280	-	-	-	S	-	-	-	associated with various cellular activities
HKDIFGKN_01569	1136177.KCA1_2814	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKDIFGKN_01570	220668.lp_3464	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HKDIFGKN_01571	220668.lp_3466	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKDIFGKN_01572	220668.lp_3471	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKDIFGKN_01573	220668.lp_3472	2.9e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HKDIFGKN_01574	220668.lp_3473	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKDIFGKN_01575	220668.lp_3474	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HKDIFGKN_01576	220668.lp_3476	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKDIFGKN_01577	220668.lp_3477	3.38e-50	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKDIFGKN_01578	220668.lp_3477	1.11e-33	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKDIFGKN_01579	60520.HR47_11240	6.61e-29	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKDIFGKN_01580	60520.HR47_11235	5.55e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKDIFGKN_01581	220668.lp_3479	5.19e-229	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKDIFGKN_01582	220668.lp_3480	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKDIFGKN_01583	220668.lp_3481	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKDIFGKN_01584	220668.lp_3482	1.92e-285	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKDIFGKN_01585	220668.lp_3483	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HKDIFGKN_01586	220668.lp_3484	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HKDIFGKN_01587	220668.lp_3485	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKDIFGKN_01588	220668.lp_3486	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HKDIFGKN_01589	220668.lp_3487	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKDIFGKN_01590	220668.lp_3488	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKDIFGKN_01591	220668.lp_3489	1.22e-246	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HKDIFGKN_01592	220668.lp_3490	2.86e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HKDIFGKN_01593	220668.lp_3491	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKDIFGKN_01594	220668.lp_3492	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKDIFGKN_01595	60520.HR47_11135	3.35e-168	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKDIFGKN_01596	60520.HR47_11130	1.33e-274	-	-	-	G	-	-	-	Transporter
HKDIFGKN_01597	60520.HR47_11125	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKDIFGKN_01598	60520.HR47_11120	1.66e-208	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKDIFGKN_01599	60520.HR47_11115	5.78e-269	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKDIFGKN_01600	220668.lp_3504	2.97e-83	-	-	-	-	-	-	-	-
HKDIFGKN_01601	220668.lp_3505	1.52e-199	estA	-	-	S	-	-	-	Putative esterase
HKDIFGKN_01602	220668.lp_3506	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HKDIFGKN_01603	220668.lp_3507	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_01604	220668.lp_3508	2.41e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKDIFGKN_01605	220668.lp_3509	6.87e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HKDIFGKN_01606	220668.lp_3510	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKDIFGKN_01607	220668.lp_3512	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_01608	220668.lp_3513	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDIFGKN_01609	220668.lp_3514	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKDIFGKN_01610	220668.lp_3525	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_01611	220668.lp_3526	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_01612	220668.lp_3527	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDIFGKN_01613	220668.lp_3529	6.54e-142	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKDIFGKN_01614	220668.lp_3529	2.18e-35	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKDIFGKN_01615	220668.lp_3530	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKDIFGKN_01616	220668.lp_3531	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKDIFGKN_01617	220668.lp_3533	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKDIFGKN_01618	220668.lp_3534	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HKDIFGKN_01620	203123.OEOE_0076	1.23e-163	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	Transporter
HKDIFGKN_01621	862514.HMPREF0623_1599	3.43e-236	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HKDIFGKN_01622	862514.HMPREF0623_1598	2.47e-307	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKDIFGKN_01623	1033837.WANG_1747	6.96e-20	-	-	-	S	-	-	-	Transglycosylase associated protein
HKDIFGKN_01625	220668.lp_2488h	4.63e-24	-	-	-	-	-	-	-	-
HKDIFGKN_01626	220668.lp_2497	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HKDIFGKN_01627	220668.lp_2498	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKDIFGKN_01628	220668.lp_2499	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01629	60520.HR47_13790	2.1e-33	-	-	-	-	-	-	-	-
HKDIFGKN_01630	220668.lp_2502	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKDIFGKN_01631	220668.lp_2503	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKDIFGKN_01632	220668.lp_2504	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HKDIFGKN_01633	220668.lp_2505	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HKDIFGKN_01634	220668.lp_2506	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HKDIFGKN_01635	220668.lp_2507	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKDIFGKN_01636	220668.lp_2508	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HKDIFGKN_01637	220668.lp_2509	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HKDIFGKN_01639	220668.lp_2512	5.13e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKDIFGKN_01640	220668.lp_2513	7.59e-64	-	-	-	-	-	-	-	-
HKDIFGKN_01641	220668.lp_2514	2.48e-124	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HKDIFGKN_01642	220668.lp_2514	1.33e-134	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HKDIFGKN_01643	220668.lp_2515	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HKDIFGKN_01644	220668.lp_2516	7.71e-32	-	-	-	-	-	-	-	-
HKDIFGKN_01646	220668.lp_2519	8.51e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_01647	220668.lp_2520	1.23e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HKDIFGKN_01648	220668.lp_2521	3.43e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HKDIFGKN_01649	220668.lp_2522	2.29e-48	-	-	-	-	-	-	-	-
HKDIFGKN_01650	220668.lp_2523	4.54e-45	-	-	-	-	-	-	-	-
HKDIFGKN_01651	220668.lp_2524	8.05e-278	-	-	-	T	-	-	-	diguanylate cyclase
HKDIFGKN_01652	220668.lp_2525	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKDIFGKN_01653	220668.lp_2526	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HKDIFGKN_01654	220668.lp_2528	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKDIFGKN_01655	220668.lp_2529	2.64e-61	-	-	-	-	-	-	-	-
HKDIFGKN_01656	220668.lp_2531	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKDIFGKN_01657	220668.lp_2532	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKDIFGKN_01658	220668.lp_2534	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKDIFGKN_01659	220668.lp_2535	5.61e-291	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HKDIFGKN_01660	220668.lp_2536	1.74e-311	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HKDIFGKN_01661	220668.lp_2537	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HKDIFGKN_01662	220668.lp_2541	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_01663	220668.lp_2542	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKDIFGKN_01664	220668.lp_2543	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01665	220668.lp_2544	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKDIFGKN_01666	220668.lp_2548	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HKDIFGKN_01667	220668.lp_2549	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HKDIFGKN_01668	220668.lp_2550	1.74e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKDIFGKN_01669	220668.lp_2551	1.9e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKDIFGKN_01670	220668.lp_2552	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HKDIFGKN_01671	220668.lp_2553	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKDIFGKN_01672	220668.lp_2554	1.49e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKDIFGKN_01673	220668.lp_2556	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKDIFGKN_01674	220668.lp_2557	7.47e-141	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKDIFGKN_01675	220668.lp_2558	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HKDIFGKN_01676	220668.lp_2559	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKDIFGKN_01677	220668.lp_2560	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKDIFGKN_01678	220668.lp_2561	5.64e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKDIFGKN_01679	220668.lp_2563	4.54e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HKDIFGKN_01680	220668.lp_2564	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HKDIFGKN_01681	220668.lp_2565	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKDIFGKN_01682	220668.lp_2566	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HKDIFGKN_01683	220668.lp_2567	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HKDIFGKN_01684	220668.lp_2568	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKDIFGKN_01685	220668.lp_2569	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HKDIFGKN_01686	220668.lp_2570	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKDIFGKN_01687	220668.lp_2572	5.48e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKDIFGKN_01688	220668.lp_2573	1.19e-45	-	-	-	-	-	-	-	-
HKDIFGKN_01689	220668.lp_2574	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKDIFGKN_01690	220668.lp_2575	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKDIFGKN_01691	220668.lp_2578	0.0	-	-	-	M	-	-	-	domain protein
HKDIFGKN_01692	220668.lp_2579	6.05e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKDIFGKN_01693	220668.lp_2580	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKDIFGKN_01694	220668.lp_2582	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HKDIFGKN_01695	220668.lp_2585	4.68e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKDIFGKN_01696	220668.lp_2586	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_01697	220668.lp_2588	1.69e-248	-	-	-	S	-	-	-	domain, Protein
HKDIFGKN_01698	220668.lp_2589	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HKDIFGKN_01699	220668.lp_2590	3e-127	-	-	-	C	-	-	-	Nitroreductase family
HKDIFGKN_01700	220668.lp_2591	5.02e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HKDIFGKN_01701	220668.lp_2593	3.68e-203	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKDIFGKN_01702	1136177.KCA1_2125	3.64e-156	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKDIFGKN_01703	1136177.KCA1_2126	1.73e-200	ccpB	-	-	K	-	-	-	lacI family
HKDIFGKN_01704	1136177.KCA1_2127	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKDIFGKN_01705	220668.lp_2604	1.43e-226	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKDIFGKN_01706	220668.lp_2606	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HKDIFGKN_01707	220668.lp_2608	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKDIFGKN_01708	220668.lp_2610	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKDIFGKN_01709	220668.lp_2612	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HKDIFGKN_01710	220668.lp_2613	2.66e-172	-	-	-	-	-	-	-	-
HKDIFGKN_01711	220668.lp_2614	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_01712	220668.lp_2615	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HKDIFGKN_01713	220668.lp_2616	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HKDIFGKN_01714	220668.lp_2620	1.88e-222	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKDIFGKN_01715	220668.lp_2621	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HKDIFGKN_01716	220668.lp_2622	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_01717	220668.lp_2623	1.86e-210	-	-	-	-	-	-	-	-
HKDIFGKN_01718	220668.lp_2624	1.23e-75	-	-	-	-	-	-	-	-
HKDIFGKN_01719	220668.lp_2625	2.8e-63	-	-	-	-	-	-	-	-
HKDIFGKN_01720	220668.lp_2629	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKDIFGKN_01721	220668.lp_2630	1.83e-37	-	-	-	-	-	-	-	-
HKDIFGKN_01722	220668.lp_2631	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HKDIFGKN_01723	220668.lp_2633	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HKDIFGKN_01724	220668.lp_2634	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKDIFGKN_01725	220668.lp_2635	3.89e-62	-	-	-	-	-	-	-	-
HKDIFGKN_01726	220668.lp_2636	2.57e-70	-	-	-	-	-	-	-	-
HKDIFGKN_01727	220668.lp_2638	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HKDIFGKN_01728	220668.lp_2641	1.65e-97	-	-	-	-	-	-	-	-
HKDIFGKN_01729	220668.lp_2642	4.15e-78	-	-	-	-	-	-	-	-
HKDIFGKN_01730	220668.lp_2643	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HKDIFGKN_01731	220668.lp_2645	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HKDIFGKN_01732	220668.lp_2652	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
HKDIFGKN_01733	220668.lp_2653	2.5e-203	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKDIFGKN_01734	220668.lp_2654	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKDIFGKN_01735	60520.HR47_14325	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKDIFGKN_01736	220668.lp_2658	3.07e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKDIFGKN_01737	220668.lp_2659	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKDIFGKN_01738	220668.lp_2660	2.35e-208	-	-	-	S	-	-	-	Putative esterase
HKDIFGKN_01739	220668.lp_2661	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_01740	60520.HR47_14350	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKDIFGKN_01741	220668.lp_2663	2.48e-178	-	-	-	-	-	-	-	-
HKDIFGKN_01742	220668.lp_2664	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKDIFGKN_01743	220668.lp_2665	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HKDIFGKN_01744	220668.lp_2666	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HKDIFGKN_01745	220668.lp_2667	1.55e-79	-	-	-	-	-	-	-	-
HKDIFGKN_01746	220668.lp_2668	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKDIFGKN_01747	220668.lp_2669	2.97e-76	-	-	-	-	-	-	-	-
HKDIFGKN_01748	220668.lp_2671	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HKDIFGKN_01749	220668.lp_2673	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HKDIFGKN_01750	220668.lp_2674	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKDIFGKN_01751	220668.lp_2675	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_01752	220668.lp_2676	3.45e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDIFGKN_01753	220668.lp_2677	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKDIFGKN_01754	220668.lp_2680	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKDIFGKN_01755	220668.lp_2681	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKDIFGKN_01756	220668.lp_2683	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HKDIFGKN_01757	220668.lp_2684	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKDIFGKN_01758	220668.lp_2685	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKDIFGKN_01759	1114972.AUAW01000027_gene735	3.59e-26	-	-	-	-	-	-	-	-
HKDIFGKN_01760	220668.lp_2688	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKDIFGKN_01761	220668.lp_2689	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HKDIFGKN_01762	220668.lp_2690	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HKDIFGKN_01763	220668.lp_2691	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKDIFGKN_01764	220668.lp_2693	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKDIFGKN_01765	220668.lp_2694	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKDIFGKN_01766	60520.HR47_14480	1.12e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HKDIFGKN_01767	220668.lp_2697	5.46e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKDIFGKN_01768	220668.lp_2698	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKDIFGKN_01769	220668.lp_2699	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKDIFGKN_01770	60520.HR47_14500	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKDIFGKN_01771	220668.lp_2701	2.76e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKDIFGKN_01772	220668.lp_2702	1.61e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKDIFGKN_01773	220668.lp_2703	2.02e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKDIFGKN_01774	1136177.KCA1_2211	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKDIFGKN_01775	220668.lp_2708	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HKDIFGKN_01776	220668.lp_2710	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKDIFGKN_01777	220668.lp_2712	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HKDIFGKN_01778	220668.lp_2713	2.61e-205	-	-	-	GM	-	-	-	NmrA-like family
HKDIFGKN_01779	220668.lp_2714	1.25e-199	-	-	-	T	-	-	-	EAL domain
HKDIFGKN_01780	220668.lp_2715	6.18e-120	-	-	-	-	-	-	-	-
HKDIFGKN_01781	220668.lp_2716	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HKDIFGKN_01782	220668.lp_2718	1.83e-157	-	-	-	E	-	-	-	Methionine synthase
HKDIFGKN_01783	220668.lp_2719	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKDIFGKN_01784	220668.lp_2720	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKDIFGKN_01785	220668.lp_2721	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKDIFGKN_01786	220668.lp_2722	4.22e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKDIFGKN_01787	220668.lp_2723	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKDIFGKN_01788	220668.lp_2724	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKDIFGKN_01789	220668.lp_2725	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKDIFGKN_01790	220668.lp_2726	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKDIFGKN_01791	220668.lp_2727	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKDIFGKN_01792	220668.lp_2728	2.87e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKDIFGKN_01793	220668.lp_2729	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKDIFGKN_01794	220668.lp_2732	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HKDIFGKN_01795	220668.lp_2733	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKDIFGKN_01796	220668.lp_2734	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HKDIFGKN_01797	220668.lp_2735	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKDIFGKN_01798	220668.lp_2736	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HKDIFGKN_01799	220668.lp_2737	6.89e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_01800	220668.lp_2738	3.04e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HKDIFGKN_01801	220668.lp_2739	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01802	220668.lp_2740	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKDIFGKN_01803	220668.lp_2741	7.91e-55	-	-	-	-	-	-	-	-
HKDIFGKN_01804	220668.lp_2742	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HKDIFGKN_01805	220668.lp_2743	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01806	220668.lp_2744	4.21e-175	-	-	-	-	-	-	-	-
HKDIFGKN_01807	220668.lp_2745	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HKDIFGKN_01808	220668.lp_2746	3.64e-46	-	-	-	-	-	-	-	-
HKDIFGKN_01809	220668.lp_2747	5.7e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKDIFGKN_01810	220668.lp_2748	1.76e-114	-	-	-	-	-	-	-	-
HKDIFGKN_01811	220668.lp_2749	1.02e-67	-	-	-	-	-	-	-	-
HKDIFGKN_01812	1136177.KCA1_2246	4.79e-13	-	-	-	-	-	-	-	-
HKDIFGKN_01813	220668.lp_2751	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKDIFGKN_01814	220668.lp_2753	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HKDIFGKN_01815	220668.lp_2754	1.52e-151	-	-	-	-	-	-	-	-
HKDIFGKN_01816	220668.lp_2755	1.21e-69	-	-	-	-	-	-	-	-
HKDIFGKN_01818	220668.lp_2757	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKDIFGKN_01819	220668.lp_2758	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKDIFGKN_01820	220668.lp_2759	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKDIFGKN_01821	220668.lp_2760	2.99e-38	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HKDIFGKN_01822	220668.lp_2761	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKDIFGKN_01823	220668.lp_2762	1.13e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HKDIFGKN_01824	220668.lp_2763	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HKDIFGKN_01825	220668.lp_2764	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKDIFGKN_01826	220668.lp_2765	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HKDIFGKN_01827	220668.lp_2766	3.48e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKDIFGKN_01828	220668.lp_2767	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HKDIFGKN_01829	220668.lp_2770	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HKDIFGKN_01830	220668.lp_2771	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKDIFGKN_01831	220668.lp_2772	6.09e-152	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_01832	220668.lp_2773	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_01833	220668.lp_2774	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKDIFGKN_01834	220668.lp_2776	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HKDIFGKN_01835	220668.lp_2777	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_01836	220668.lp_2778	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDIFGKN_01837	1136177.KCA1_2274	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HKDIFGKN_01838	1136177.KCA1_2275	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKDIFGKN_01839	220668.lp_2782	3.69e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HKDIFGKN_01840	220668.lp_2783	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HKDIFGKN_01841	220668.lp_2785	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HKDIFGKN_01842	220668.lp_2786	7.63e-107	-	-	-	-	-	-	-	-
HKDIFGKN_01843	220668.lp_2787	5.9e-195	-	-	-	S	-	-	-	hydrolase
HKDIFGKN_01844	220668.lp_2788	6.86e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKDIFGKN_01845	220668.lp_2789	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HKDIFGKN_01846	220668.lp_2790	3.95e-224	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKDIFGKN_01847	220668.lp_2792	1.54e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKDIFGKN_01848	220668.lp_2793	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HKDIFGKN_01849	220668.lp_2794	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKDIFGKN_01850	220668.lp_2795	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKDIFGKN_01851	220668.lp_2796	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HKDIFGKN_01852	220668.lp_2797	4.3e-44	-	-	-	-	-	-	-	-
HKDIFGKN_01853	220668.lp_2798	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HKDIFGKN_01854	220668.lp_2799	0.0	ycaM	-	-	E	-	-	-	amino acid
HKDIFGKN_01855	220668.lp_2800	1.41e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKDIFGKN_01856	220668.lp_2802	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HKDIFGKN_01857	220668.lp_2803	2.43e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKDIFGKN_01858	220668.lp_2804	2.16e-208	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_01860	220668.lp_0939	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKDIFGKN_01861	220668.lp_0938	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKDIFGKN_01862	220668.lp_0937	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HKDIFGKN_01863	220668.lp_0935	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
HKDIFGKN_01864	220668.lp_0934	4.46e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKDIFGKN_01865	60520.HR47_05200	1.22e-210	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKDIFGKN_01866	220668.lp_0931	9.6e-191	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HKDIFGKN_01867	220668.lp_0930	8.55e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKDIFGKN_01868	220668.lp_0929	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKDIFGKN_01869	220668.lp_0928	5.74e-32	-	-	-	-	-	-	-	-
HKDIFGKN_01870	220668.lp_0927	1.37e-116	-	-	-	-	-	-	-	-
HKDIFGKN_01871	220668.lp_0926	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HKDIFGKN_01872	220668.lp_0925	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HKDIFGKN_01873	220668.lp_0924	2.09e-60	-	-	-	S	-	-	-	MORN repeat
HKDIFGKN_01874	220668.lp_0923	5.56e-262	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HKDIFGKN_01875	220668.lp_0922	1.33e-269	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HKDIFGKN_01876	60520.HR47_10240	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDIFGKN_01877	60520.HR47_10235	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
HKDIFGKN_01878	220668.lp_0921	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKDIFGKN_01879	60520.HR47_05115	9.51e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_01880	220668.lp_0917	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_01881	220668.lp_0915	1.08e-71	-	-	-	-	-	-	-	-
HKDIFGKN_01882	278197.PEPE_0973	3.32e-96	-	-	-	-	-	-	-	-
HKDIFGKN_01883	1400520.LFAB_17370	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDIFGKN_01884	1400520.LFAB_17370	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDIFGKN_01885	913848.AELK01000011_gene1157	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDIFGKN_01886	220668.lp_2011	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
HKDIFGKN_01888	562983.HMPREF0433_01301	1.04e-139	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
HKDIFGKN_01890	220668.lp_2397	2.91e-177	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HKDIFGKN_01891	220668.lp_2396	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKDIFGKN_01892	220668.lp_2395	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01893	220668.lp_2394	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKDIFGKN_01894	220668.lp_2393	8.87e-181	-	-	-	-	-	-	-	-
HKDIFGKN_01895	220668.lp_2391	1.33e-77	-	-	-	-	-	-	-	-
HKDIFGKN_01896	220668.lp_2390	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HKDIFGKN_01897	220668.lp_2388	8.57e-41	-	-	-	-	-	-	-	-
HKDIFGKN_01898	220668.lp_2385	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HKDIFGKN_01899	220668.lp_2384	4.07e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKDIFGKN_01900	220668.lp_2382	3.04e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HKDIFGKN_01901	220668.lp_2380	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HKDIFGKN_01902	220668.lp_2379	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKDIFGKN_01903	220668.lp_2378	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKDIFGKN_01904	220668.lp_2377	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKDIFGKN_01905	220668.lp_2376	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKDIFGKN_01906	220668.lp_2375	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKDIFGKN_01907	1136177.KCA1_2007	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKDIFGKN_01908	220668.lp_2371	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HKDIFGKN_01909	220668.lp_2370	7.99e-164	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKDIFGKN_01910	1400520.LFAB_10700	3.66e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKDIFGKN_01911	1136177.KCA1_2003	2.68e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKDIFGKN_01912	220668.lp_2367	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKDIFGKN_01913	220668.lp_2366	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKDIFGKN_01914	220668.lp_2365	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKDIFGKN_01915	220668.lp_2364	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKDIFGKN_01916	220668.lp_2363	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKDIFGKN_01917	220668.lp_2361	4.85e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKDIFGKN_01918	220668.lp_2360	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKDIFGKN_01919	220668.lp_2359	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HKDIFGKN_01920	220668.lp_2358	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HKDIFGKN_01921	220668.lp_2357	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HKDIFGKN_01922	220668.lp_2354	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKDIFGKN_01923	220668.lp_2353	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HKDIFGKN_01924	220668.lp_2352	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKDIFGKN_01925	60520.HR47_13195	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_01926	220668.lp_2350	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKDIFGKN_01927	220668.lp_2349	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKDIFGKN_01928	220668.lp_2347	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HKDIFGKN_01929	220668.lp_2346	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKDIFGKN_01930	220668.lp_2345	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKDIFGKN_01931	220668.lp_2344	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HKDIFGKN_01932	220668.lp_2342	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKDIFGKN_01933	220668.lp_2341	8.1e-261	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKDIFGKN_01934	1136177.KCA1_1981	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HKDIFGKN_01935	220668.lp_2339	1.34e-52	-	-	-	-	-	-	-	-
HKDIFGKN_01936	220668.lp_2337	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKDIFGKN_01937	220668.lp_2336	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HKDIFGKN_01938	220668.lp_2335	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDIFGKN_01939	220668.lp_2334	1.51e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HKDIFGKN_01940	220668.lp_2333	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKDIFGKN_01941	220668.lp_2332	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HKDIFGKN_01942	220668.lp_2331	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKDIFGKN_01943	220668.lp_2330	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HKDIFGKN_01944	220668.lp_2328	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKDIFGKN_01945	220668.lp_2326	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKDIFGKN_01946	220668.lp_2325	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKDIFGKN_01947	220668.lp_2324	7.78e-300	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HKDIFGKN_01948	220668.lp_2323	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKDIFGKN_01949	220668.lp_2322	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKDIFGKN_01950	220668.lp_2321	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKDIFGKN_01951	220668.lp_2320	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKDIFGKN_01952	220668.lp_2319	1.01e-210	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HKDIFGKN_01953	220668.lp_2318	1.08e-183	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKDIFGKN_01954	220668.lp_2317	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HKDIFGKN_01955	220668.lp_2316	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKDIFGKN_01956	220668.lp_2315	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HKDIFGKN_01957	220668.lp_2314	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDIFGKN_01958	220668.lp_2313	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_01959	220668.lp_2312	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKDIFGKN_01960	220668.lp_2308	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKDIFGKN_01961	220668.lp_2306	3.55e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HKDIFGKN_01962	220668.lp_2305	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HKDIFGKN_01963	220668.lp_2304	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HKDIFGKN_01964	220668.lp_2303	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKDIFGKN_01965	220668.lp_2302	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKDIFGKN_01966	220668.lp_2301	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKDIFGKN_01967	220668.lp_2300	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKDIFGKN_01968	220668.lp_2299	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HKDIFGKN_01969	220668.lp_2298	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKDIFGKN_01970	220668.lp_2297	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKDIFGKN_01971	220668.lp_2006	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HKDIFGKN_01972	220668.lp_2292	1.3e-91	-	-	-	-	-	-	-	-
HKDIFGKN_01973	220668.lp_2290	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKDIFGKN_01974	220668.lp_2289	4.02e-114	-	-	-	-	-	-	-	-
HKDIFGKN_01975	220668.lp_2287	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKDIFGKN_01976	220668.lp_2286	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKDIFGKN_01977	220668.lp_2285	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKDIFGKN_01978	220668.lp_2282	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKDIFGKN_01979	220668.lp_2281	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKDIFGKN_01980	220668.lp_2280	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKDIFGKN_01981	220668.lp_2279	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HKDIFGKN_01982	220668.lp_2278	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKDIFGKN_01983	220668.lp_2277	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKDIFGKN_01984	220668.lp_2275	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKDIFGKN_01985	220668.lp_2274	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKDIFGKN_01986	220668.lp_2273	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKDIFGKN_01987	220668.lp_2272	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKDIFGKN_01988	220668.lp_2271	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKDIFGKN_01989	220668.lp_2270	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKDIFGKN_01990	220668.lp_2269	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HKDIFGKN_01991	220668.lp_2268	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKDIFGKN_01992	220668.lp_2267	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKDIFGKN_01993	220668.lp_2266	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HKDIFGKN_01994	220668.lp_2265	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HKDIFGKN_01995	220668.lp_2264	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKDIFGKN_01996	220668.lp_2263	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKDIFGKN_01997	220668.lp_2262	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HKDIFGKN_01998	220668.lp_2261	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKDIFGKN_01999	220668.lp_2260	1.6e-96	-	-	-	-	-	-	-	-
HKDIFGKN_02000	220668.lp_2259	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDIFGKN_02001	220668.lp_2258	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKDIFGKN_02002	220668.lp_2256	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HKDIFGKN_02003	220668.lp_2255	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKDIFGKN_02004	220668.lp_2254	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HKDIFGKN_02005	220668.lp_2253	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HKDIFGKN_02006	220668.lp_2251	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKDIFGKN_02007	220668.lp_2249	1.48e-223	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HKDIFGKN_02008	220668.lp_2248	7.23e-241	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HKDIFGKN_02009	220668.lp_2247	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HKDIFGKN_02010	220668.lp_2246	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HKDIFGKN_02011	60520.HR47_12770	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HKDIFGKN_02012	220668.lp_2244	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HKDIFGKN_02014	220668.lp_2243	2.59e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HKDIFGKN_02015	220668.lp_2242	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKDIFGKN_02016	220668.lp_2240	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKDIFGKN_02017	220668.lp_2238	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKDIFGKN_02018	220668.lp_2237	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKDIFGKN_02019	220668.lp_2236	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HKDIFGKN_02020	220668.lp_2235	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKDIFGKN_02021	220668.lp_2234	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HKDIFGKN_02022	220668.lp_2232	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HKDIFGKN_02023	220668.lp_2231c	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKDIFGKN_02024	220668.lp_2231b	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HKDIFGKN_02025	220668.lp_2231a	1.11e-84	-	-	-	-	-	-	-	-
HKDIFGKN_02026	220668.lp_0473	4.31e-179	-	-	-	-	-	-	-	-
HKDIFGKN_02027	220668.lp_0472	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HKDIFGKN_02028	220668.lp_0471	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKDIFGKN_02029	220668.lp_0469	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKDIFGKN_02030	220668.lp_0467	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKDIFGKN_02031	220668.lp_0466	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HKDIFGKN_02032	220668.lp_0376	5.3e-49	-	-	-	-	-	-	-	-
HKDIFGKN_02033	220668.lp_0381	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
HKDIFGKN_02034	220668.lp_0464	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKDIFGKN_02035	220668.lp_0463	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKDIFGKN_02036	220668.lp_0461	2.22e-229	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HKDIFGKN_02037	220668.lp_0460	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKDIFGKN_02038	220668.lp_0459	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HKDIFGKN_02039	220668.lp_0458	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKDIFGKN_02040	220668.lp_0457	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKDIFGKN_02041	220668.lp_0456	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HKDIFGKN_02043	1136177.KCA1_0381	2.53e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HKDIFGKN_02044	220668.lp_0455	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HKDIFGKN_02045	220668.lp_0454	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKDIFGKN_02046	220668.lp_0452	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HKDIFGKN_02047	220668.lp_0450	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HKDIFGKN_02048	220668.lp_0449	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HKDIFGKN_02049	220668.lp_0448	1.09e-227	-	-	-	-	-	-	-	-
HKDIFGKN_02050	220668.lp_0447	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HKDIFGKN_02051	220668.lp_0446	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKDIFGKN_02052	220668.lp_0443	1.2e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKDIFGKN_02053	60520.HR47_08850	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKDIFGKN_02054	60520.HR47_08855	5.9e-46	-	-	-	-	-	-	-	-
HKDIFGKN_02055	220668.lp_0438	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKDIFGKN_02056	60520.HR47_08865	9.68e-34	-	-	-	-	-	-	-	-
HKDIFGKN_02057	220668.lp_0436	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_02058	220668.lp_0435	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HKDIFGKN_02059	220668.lp_0434	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKDIFGKN_02060	60520.HR47_08885	5.87e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HKDIFGKN_02061	220668.lp_0432	0.0	-	-	-	L	-	-	-	DNA helicase
HKDIFGKN_02062	220668.lp_0431	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HKDIFGKN_02063	220668.lp_0429	1.59e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_02064	220668.lp_0428	4.56e-144	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_02065	220668.lp_0426	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_02066	60520.HR47_08915	1.83e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_02067	220668.lp_0424	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HKDIFGKN_02068	220668.lp_0423	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKDIFGKN_02069	220668.lp_0422	1.49e-07	-	-	-	-	-	-	-	-
HKDIFGKN_02070	220668.lp_0421	1.93e-31	plnF	-	-	-	-	-	-	-
HKDIFGKN_02071	220668.lp_0419	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_02072	220668.lp_0418	3.02e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKDIFGKN_02073	1136177.KCA1_0354	9.77e-100	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKDIFGKN_02074	525318.HMPREF0497_2925	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HKDIFGKN_02075	220668.45723554	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HKDIFGKN_02076	1400520.LFAB_17345	5.3e-49	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKDIFGKN_02077	1423807.BACO01000083_gene2414	4.28e-81	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKDIFGKN_02078	713605.ADHG01000001_gene552	6.32e-08	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HKDIFGKN_02079	1400520.LFAB_17390	7.07e-106	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HKDIFGKN_02080	1423807.BACO01000083_gene2412	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKDIFGKN_02081	1400520.LFAB_17380	1.13e-219	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HKDIFGKN_02082	1423807.BACO01000083_gene2410	3.29e-232	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HKDIFGKN_02083	748671.LCRIS_00539	1.52e-129	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HKDIFGKN_02084	860228.Ccan_23150	1.46e-21	-	-	-	S	-	-	-	FRG
HKDIFGKN_02085	713605.ADHG01000001_gene551	3.77e-278	-	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_02086	713605.ADHG01000001_gene550	1.62e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKDIFGKN_02087	713605.ADHG01000001_gene552	7.83e-235	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HKDIFGKN_02088	1074451.CRL705_1644	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HKDIFGKN_02089	913848.AELK01000212_gene2692	5.13e-63	-	-	-	L	-	-	-	Transposase
HKDIFGKN_02090	1400520.LFAB_17600	1.75e-184	-	-	-	D	-	-	-	AAA domain
HKDIFGKN_02091	1400520.LFAB_17595	1.7e-45	-	-	-	-	-	-	-	-
HKDIFGKN_02093	278197.PEPE_0498	1.03e-156	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKDIFGKN_02094	278197.PEPE_0498	2.85e-50	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKDIFGKN_02095	1400520.LFAB_01550	5.82e-48	-	-	-	M	-	-	-	LysM domain protein
HKDIFGKN_02096	1400520.LFAB_17365	8.75e-138	-	-	-	L	-	-	-	Resolvase, N terminal domain
HKDIFGKN_02097	1400520.LFAB_17360	2.14e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKDIFGKN_02098	1114972.AUAW01000027_gene722	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKDIFGKN_02099	1114972.AUAW01000027_gene721	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HKDIFGKN_02100	543734.LCABL_06250	7.81e-247	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKDIFGKN_02101	525318.HMPREF0497_2979	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKDIFGKN_02102	585524.HMPREF0493_0553	6.75e-181	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HKDIFGKN_02103	220668.lp_0304	4.73e-53	-	-	-	M	-	-	-	LysM domain protein
HKDIFGKN_02104	334390.LAF_0161	5.29e-225	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HKDIFGKN_02105	1302286.BAOT01000072_gene2188	2.97e-234	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HKDIFGKN_02106	1291743.LOSG293_190030	1.14e-143	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HKDIFGKN_02107	1423806.JCM15457_1481	9.17e-126	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HKDIFGKN_02108	1114972.AUAW01000027_gene720	1.08e-219	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKDIFGKN_02109	1139219.I569_01456	2.7e-18	XK27_07075	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_02119	279808.SH2391	4.81e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
HKDIFGKN_02121	1291743.LOSG293_220180	1.85e-117	-	-	-	M	-	-	-	CHAP domain
HKDIFGKN_02123	1123312.KB904574_gene83	4.78e-118	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HKDIFGKN_02127	714313.LSA_2p00010	1.06e-113	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
HKDIFGKN_02128	1400520.LFAB_17600	1.55e-78	-	-	-	D	-	-	-	AAA domain
HKDIFGKN_02130	1138822.PL11_10540	9.46e-298	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKDIFGKN_02131	1133569.AHYZ01000003_gene560	2.4e-47	-	-	-	-	-	-	-	-
HKDIFGKN_02132	1138822.PL11_10550	2.54e-44	-	-	-	-	-	-	-	-
HKDIFGKN_02133	387344.LVIS_1260	1.66e-62	-	-	-	KLT	-	-	-	serine threonine protein kinase
HKDIFGKN_02134	1291743.LOSG293_220270	4.14e-126	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKDIFGKN_02136	1114972.AUAW01000013_gene1036	2.84e-177	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HKDIFGKN_02137	1033806.HTIA_2374	7.12e-06	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKDIFGKN_02138	220668.lp_1283	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKDIFGKN_02139	220668.lp_1281	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HKDIFGKN_02140	220668.lp_1280	3.91e-289	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKDIFGKN_02141	220668.lp_1278	9.32e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKDIFGKN_02142	220668.lp_1277	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKDIFGKN_02143	220668.lp_1276	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKDIFGKN_02144	220668.lp_1275	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKDIFGKN_02145	220668.lp_1274	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKDIFGKN_02146	1136177.KCA1_1042	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HKDIFGKN_02147	60520.HR47_00950	5.6e-41	-	-	-	-	-	-	-	-
HKDIFGKN_02148	220668.lp_1269	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKDIFGKN_02149	220668.lp_1268	2.5e-132	-	-	-	L	-	-	-	Integrase
HKDIFGKN_02150	220668.lp_1267	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKDIFGKN_02151	220668.lp_1265	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKDIFGKN_02152	220668.lp_1264	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKDIFGKN_02153	220668.lp_1263	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKDIFGKN_02154	220668.lp_1262	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKDIFGKN_02155	220668.lp_1261	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKDIFGKN_02156	220668.lp_1260	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HKDIFGKN_02157	60520.HR47_01000	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKDIFGKN_02158	220668.lp_1258	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HKDIFGKN_02159	220668.lp_1257	1.49e-252	-	-	-	M	-	-	-	MucBP domain
HKDIFGKN_02160	220668.lp_1256	0.0	-	-	-	-	-	-	-	-
HKDIFGKN_02161	220668.lp_1255	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKDIFGKN_02162	220668.lp_1253	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKDIFGKN_02163	220668.lp_1251	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HKDIFGKN_02164	220668.lp_1250	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKDIFGKN_02165	220668.lp_1249	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HKDIFGKN_02166	220668.lp_1248	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKDIFGKN_02167	220668.lp_1247	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HKDIFGKN_02168	220668.lp_1245	1.04e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKDIFGKN_02169	220668.lp_1244	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HKDIFGKN_02170	1400520.LFAB_05505	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HKDIFGKN_02171	220668.lp_1242	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HKDIFGKN_02172	220668.lp_1241	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HKDIFGKN_02173	220668.lp_1240	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HKDIFGKN_02174	220668.lp_1239	1.34e-168	-	-	-	-	-	-	-	-
HKDIFGKN_02175	220668.lp_1238	1.68e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HKDIFGKN_02176	220668.lp_1237	5.5e-34	-	-	-	-	-	-	-	-
HKDIFGKN_02177	220668.lp_1236	1.95e-41	-	-	-	-	-	-	-	-
HKDIFGKN_02178	220668.lp_1235	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HKDIFGKN_02179	220668.lp_1234	9.02e-70	-	-	-	-	-	-	-	-
HKDIFGKN_02180	1074451.CRL705_1644	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HKDIFGKN_02181	1123500.ATUU01000001_gene167	8.1e-199	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HKDIFGKN_02182	1423807.BACO01000083_gene2409	3.66e-106	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDIFGKN_02183	1423816.BACQ01000033_gene1402	1.55e-50	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDIFGKN_02184	1114972.AUAW01000003_gene1289	4.77e-86	-	-	-	L	-	-	-	Helix-turn-helix domain
HKDIFGKN_02185	220668.lp_1175	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKDIFGKN_02186	220668.lp_1174	1.95e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKDIFGKN_02187	220668.lp_1173	3.34e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKDIFGKN_02188	220668.lp_1171	3.3e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HKDIFGKN_02189	220668.lp_1169	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKDIFGKN_02190	220668.lp_1168	2.9e-139	-	-	-	-	-	-	-	-
HKDIFGKN_02191	220668.lp_1166	7.62e-97	-	-	-	-	-	-	-	-
HKDIFGKN_02193	220668.lp_1165	3.21e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_02194	220668.lp_1164	3.15e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_02195	220668.lp_1163	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HKDIFGKN_02197	220668.lp_1162	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HKDIFGKN_02198	220668.lp_1161	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HKDIFGKN_02199	1136177.KCA1_0934	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKDIFGKN_02200	220668.lp_1159	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HKDIFGKN_02201	220668.lp_1158	1.9e-186	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKDIFGKN_02202	220668.lp_1157	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HKDIFGKN_02203	220668.lp_1156	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_02204	220668.lp_1155	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_02205	220668.lp_1154	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKDIFGKN_02206	220668.lp_1153	2.26e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_02207	220668.lp_1151	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKDIFGKN_02208	220668.lp_1150	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HKDIFGKN_02209	220668.lp_1149	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKDIFGKN_02210	220668.lp_1148	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKDIFGKN_02211	220668.lp_1147	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKDIFGKN_02212	220668.lp_1146	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HKDIFGKN_02213	220668.lp_1145	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKDIFGKN_02214	220668.lp_1144	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKDIFGKN_02215	220668.lp_1141	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKDIFGKN_02216	220668.lp_1140	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HKDIFGKN_02217	220668.lp_1139	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKDIFGKN_02218	220668.lp_1138	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HKDIFGKN_02219	220668.lp_1136	7.78e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKDIFGKN_02220	220668.lp_1135	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKDIFGKN_02221	220668.lp_1134	2.53e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKDIFGKN_02222	60520.HR47_09980	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKDIFGKN_02223	220668.lp_1129	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKDIFGKN_02224	220668.lp_1128	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKDIFGKN_02225	220668.lp_1126	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HKDIFGKN_02226	220668.lp_1125	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HKDIFGKN_02227	220668.lp_1124	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HKDIFGKN_02228	220668.lp_1123	6.07e-33	-	-	-	-	-	-	-	-
HKDIFGKN_02229	220668.lp_1121	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKDIFGKN_02230	220668.lp_1120	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKDIFGKN_02231	220668.lp_1119	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HKDIFGKN_02232	220668.lp_1118	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HKDIFGKN_02233	220668.lp_1116	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HKDIFGKN_02234	220668.lp_1115	4.35e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HKDIFGKN_02235	220668.lp_1114	5.03e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKDIFGKN_02236	220668.lp_1113	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKDIFGKN_02237	220668.lp_1112	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKDIFGKN_02238	220668.lp_1109	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HKDIFGKN_02239	220668.lp_1108	9.11e-208	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HKDIFGKN_02240	220668.lp_1107	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HKDIFGKN_02241	220668.lp_1106	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKDIFGKN_02242	220668.lp_1105	1.11e-263	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HKDIFGKN_02243	220668.lp_1103	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HKDIFGKN_02244	220668.lp_1102	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKDIFGKN_02245	220668.lp_1101	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKDIFGKN_02246	220668.lp_1098	1.18e-66	-	-	-	-	-	-	-	-
HKDIFGKN_02247	220668.lp_1097	4.26e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKDIFGKN_02248	220668.lp_1096	1.76e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKDIFGKN_02249	220668.lp_1095	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKDIFGKN_02250	220668.lp_1093	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKDIFGKN_02251	220668.lp_1092	6.07e-252	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_02252	220668.lp_1090	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HKDIFGKN_02253	220668.lp_1089	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HKDIFGKN_02254	220668.lp_1088	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKDIFGKN_02255	220668.lp_1087	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKDIFGKN_02256	220668.lp_1086	1.33e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKDIFGKN_02257	220668.lp_1085	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HKDIFGKN_02258	220668.lp_1084	1.81e-193	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKDIFGKN_02259	220668.lp_1083	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKDIFGKN_02260	220668.lp_1082	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HKDIFGKN_02261	220668.lp_1081	2.02e-234	-	-	-	S	-	-	-	Membrane
HKDIFGKN_02262	220668.lp_1079	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKDIFGKN_02263	1136177.KCA1_0857	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKDIFGKN_02264	1136177.KCA1_0856	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKDIFGKN_02265	220668.lp_1076	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKDIFGKN_02266	220668.lp_1075	4.82e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKDIFGKN_02267	220668.lp_1074	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKDIFGKN_02268	220668.lp_1073	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKDIFGKN_02269	220668.lp_1072	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKDIFGKN_02270	220668.lp_1070	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HKDIFGKN_02271	220668.lp_1069	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKDIFGKN_02272	220668.lp_1068	4.42e-111	-	-	-	S	-	-	-	NusG domain II
HKDIFGKN_02273	220668.lp_1067	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HKDIFGKN_02274	220668.lp_1066	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKDIFGKN_02275	220668.lp_1063	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKDIFGKN_02276	220668.lp_1062	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKDIFGKN_02277	1400520.LFAB_04735	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKDIFGKN_02278	220668.lp_1060	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKDIFGKN_02279	1136177.KCA1_0840	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKDIFGKN_02280	220668.lp_1058	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKDIFGKN_02281	220668.lp_1056	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKDIFGKN_02282	1136177.KCA1_0837	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKDIFGKN_02283	220668.lp_1054	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HKDIFGKN_02284	1136177.KCA1_0835	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKDIFGKN_02285	220668.lp_1052	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKDIFGKN_02286	220668.lp_1051	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKDIFGKN_02287	1136177.KCA1_0832	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKDIFGKN_02288	1136177.KCA1_0830	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKDIFGKN_02289	220668.lp_1046	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKDIFGKN_02290	220668.lp_1045	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKDIFGKN_02291	1136177.KCA1_0827	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKDIFGKN_02292	1136177.KCA1_0826	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKDIFGKN_02293	220668.lp_1041	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKDIFGKN_02294	1136177.KCA1_0824	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKDIFGKN_02295	1136177.KCA1_0823	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKDIFGKN_02296	1136177.KCA1_0822	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKDIFGKN_02297	220668.lp_1036	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKDIFGKN_02298	220668.lp_1035	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKDIFGKN_02299	220668.lp_1034	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKDIFGKN_02300	220668.lp_1033	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKDIFGKN_02301	1136177.KCA1_0817	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKDIFGKN_02302	220668.lp_1027	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKDIFGKN_02303	1136177.KCA1_0815	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKDIFGKN_02304	220668.lp_1025	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKDIFGKN_02305	220668.lp_1023	3.14e-130	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HKDIFGKN_02306	220668.lp_1022	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKDIFGKN_02307	60520.HR47_09545	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKDIFGKN_02308	220668.lp_1020	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_02309	60520.HR47_09535	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKDIFGKN_02310	220668.lp_1018	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HKDIFGKN_02318	220668.lp_1012	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKDIFGKN_02319	220668.lp_1011	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKDIFGKN_02320	220668.lp_1010	7.48e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HKDIFGKN_02321	220668.lp_1008	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HKDIFGKN_02322	220668.lp_1005	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKDIFGKN_02323	220668.lp_1004	5.68e-117	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02324	220668.lp_1003	3.54e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKDIFGKN_02325	220668.lp_1002	1.58e-197	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKDIFGKN_02326	220668.lp_1001	4.15e-153	-	-	-	I	-	-	-	phosphatase
HKDIFGKN_02327	220668.lp_1000	7.84e-241	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKDIFGKN_02328	220668.lp_0999	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKDIFGKN_02329	220668.lp_0998	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKDIFGKN_02330	220668.lp_0997	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKDIFGKN_02331	220668.lp_0996	8.43e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HKDIFGKN_02332	220668.lp_0995	1.36e-77	-	-	-	-	-	-	-	-
HKDIFGKN_02333	220668.lp_0992	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKDIFGKN_02334	220668.lp_0991	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKDIFGKN_02335	220668.lp_0990	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKDIFGKN_02336	220668.lp_0988	2.94e-170	-	-	-	-	-	-	-	-
HKDIFGKN_02337	220668.lp_0984	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKDIFGKN_02338	220668.lp_0982	2.03e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HKDIFGKN_02339	220668.lp_0981	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HKDIFGKN_02340	220668.lp_0980	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKDIFGKN_02341	220668.lp_0979	4.88e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKDIFGKN_02342	220668.lp_0977	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKDIFGKN_02343	220668.lp_0975	0.0	xylP2	-	-	G	-	-	-	symporter
HKDIFGKN_02344	220668.lp_0973	4.24e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKDIFGKN_02345	220668.lp_0972	3.33e-64	-	-	-	-	-	-	-	-
HKDIFGKN_02346	220668.lp_0971	1.24e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HKDIFGKN_02347	220668.lp_0970	4.09e-131	-	-	-	K	-	-	-	FR47-like protein
HKDIFGKN_02348	220668.lp_0969	4.18e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HKDIFGKN_02349	220668.lp_0968	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HKDIFGKN_02350	220668.lp_0967	5.55e-244	-	-	-	-	-	-	-	-
HKDIFGKN_02351	220668.lp_0966	4.13e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKDIFGKN_02352	220668.lp_0965	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDIFGKN_02353	220668.lp_0963	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKDIFGKN_02354	220668.lp_0962	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKDIFGKN_02355	220668.lp_0961	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HKDIFGKN_02356	220668.lp_0960a	9.05e-55	-	-	-	-	-	-	-	-
HKDIFGKN_02357	220668.lp_0960	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKDIFGKN_02358	220668.lp_0959	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDIFGKN_02359	60520.HR47_09275	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HKDIFGKN_02360	220668.lp_0956	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKDIFGKN_02361	220668.lp_0955	4.03e-150	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKDIFGKN_02362	220668.lp_0954	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02364	220668.lp_0952	0.0	-	-	-	C	-	-	-	FMN_bind
HKDIFGKN_02365	220668.lp_0951	1.37e-220	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02366	220668.lp_0950	4.35e-61	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_02367	220668.lp_0950	4.31e-11	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_02368	220668.lp_0949	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
HKDIFGKN_02369	220668.lp_0948	1.27e-115	-	-	-	S	-	-	-	AAA domain
HKDIFGKN_02370	543734.LCABL_25980	1.42e-08	-	-	-	-	-	-	-	-
HKDIFGKN_02371	220668.lp_0946	0.0	-	-	-	M	-	-	-	MucBP domain
HKDIFGKN_02372	220668.lp_0945	4.85e-119	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HKDIFGKN_02390	1136177.KCA1_1475	1.77e-35	-	-	-	-	-	-	-	-
HKDIFGKN_02391	1136177.KCA1_1474	4.9e-76	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HKDIFGKN_02392	1136177.KCA1_1473	0.0	-	-	-	L	-	-	-	Transposase IS66 family
HKDIFGKN_02393	220668.lp_2230	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HKDIFGKN_02394	220668.lp_2229	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKDIFGKN_02395	220668.lp_2228	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKDIFGKN_02396	220668.lp_2227	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKDIFGKN_02397	220668.lp_2226	8.5e-79	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKDIFGKN_02398	220668.lp_2226	1.24e-137	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKDIFGKN_02399	220668.lp_2225	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HKDIFGKN_02400	220668.lp_2224	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HKDIFGKN_02401	220668.lp_2223	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKDIFGKN_02402	220668.lp_2222	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKDIFGKN_02403	220668.lp_2221	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKDIFGKN_02404	220668.lp_2220	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HKDIFGKN_02405	220668.lp_2219	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HKDIFGKN_02406	220668.lp_2218	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKDIFGKN_02407	220668.lp_2217	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HKDIFGKN_02408	220668.lp_2216	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKDIFGKN_02409	220668.lp_2215	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HKDIFGKN_02411	220668.lp_2213	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKDIFGKN_02412	220668.lp_2212	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HKDIFGKN_02413	220668.lp_2211	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKDIFGKN_02414	220668.lp_2210	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKDIFGKN_02415	220668.lp_2206	1.67e-222	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKDIFGKN_02416	220668.lp_2205	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HKDIFGKN_02417	220668.lp_2203	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKDIFGKN_02418	220668.lp_2202	5.82e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKDIFGKN_02419	220668.lp_2201	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HKDIFGKN_02420	220668.lp_2200	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKDIFGKN_02421	220668.lp_2199	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKDIFGKN_02422	220668.lp_2197	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKDIFGKN_02423	220668.lp_2196	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKDIFGKN_02424	220668.lp_2195	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKDIFGKN_02425	220668.lp_2194	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKDIFGKN_02426	220668.lp_2193	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKDIFGKN_02427	220668.lp_2192	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKDIFGKN_02428	220668.lp_2191	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HKDIFGKN_02429	220668.lp_2190	5.9e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HKDIFGKN_02430	220668.lp_2189	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HKDIFGKN_02431	220668.lp_2187	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKDIFGKN_02432	220668.lp_2185	2e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKDIFGKN_02433	220668.lp_2183	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HKDIFGKN_02434	220668.lp_2182	7.74e-47	-	-	-	-	-	-	-	-
HKDIFGKN_02435	220668.lp_2181	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKDIFGKN_02436	220668.lp_2180	4.88e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKDIFGKN_02437	220668.lp_2179	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HKDIFGKN_02438	220668.lp_2178	1.53e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKDIFGKN_02439	220668.lp_2177	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HKDIFGKN_02440	220668.lp_2176	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HKDIFGKN_02441	220668.lp_2175	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HKDIFGKN_02442	220668.lp_2174	2.82e-43	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKDIFGKN_02443	220668.lp_2174	2.42e-174	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKDIFGKN_02444	220668.lp_2173	0.0	-	-	-	N	-	-	-	domain, Protein
HKDIFGKN_02445	220668.lp_2170	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HKDIFGKN_02446	220668.lp_2169	1.02e-155	-	-	-	S	-	-	-	repeat protein
HKDIFGKN_02447	220668.lp_2168	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKDIFGKN_02448	220668.lp_2166	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKDIFGKN_02449	220668.lp_2162	9.21e-169	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HKDIFGKN_02450	220668.lp_2160	2.16e-39	-	-	-	-	-	-	-	-
HKDIFGKN_02451	220668.lp_2159	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKDIFGKN_02452	220668.lp_2158	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKDIFGKN_02453	220668.lp_2157	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKDIFGKN_02454	220668.lp_2156	6.45e-111	-	-	-	-	-	-	-	-
HKDIFGKN_02455	220668.lp_2155	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKDIFGKN_02456	220668.lp_2154	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKDIFGKN_02457	1136177.KCA1_1824	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HKDIFGKN_02458	220668.lp_2152	9.59e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKDIFGKN_02459	220668.lp_2151	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HKDIFGKN_02460	220668.lp_2150	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HKDIFGKN_02461	220668.lp_2149	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HKDIFGKN_02462	220668.lp_2147	7.1e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HKDIFGKN_02463	220668.lp_2146	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKDIFGKN_02464	220668.lp_2145	4.19e-122	-	-	-	-	-	-	-	-
HKDIFGKN_02465	220668.lp_2145	4.94e-129	-	-	-	-	-	-	-	-
HKDIFGKN_02466	220668.lp_2143	9.51e-135	-	-	-	-	-	-	-	-
HKDIFGKN_02467	220668.lp_2142	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HKDIFGKN_02468	220668.lp_2141	8.77e-114	-	-	-	-	-	-	-	-
HKDIFGKN_02469	220668.lp_2141	6.35e-236	-	-	-	-	-	-	-	-
HKDIFGKN_02470	220668.lp_2137	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKDIFGKN_02471	220668.lp_2136	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKDIFGKN_02472	220668.lp_2135	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HKDIFGKN_02473	220668.lp_2134	8.61e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HKDIFGKN_02474	220668.lp_2133	7.04e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKDIFGKN_02475	220668.lp_2132	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKDIFGKN_02476	220668.lp_2131	2.1e-161	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HKDIFGKN_02477	220668.lp_2130	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HKDIFGKN_02478	220668.lp_2129	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKDIFGKN_02479	220668.lp_2128	8.43e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKDIFGKN_02480	220668.lp_2126	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKDIFGKN_02481	1136177.KCA1_1802	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKDIFGKN_02482	220668.lp_2124	1.82e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKDIFGKN_02483	220668.lp_2123	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKDIFGKN_02484	220668.lp_2122	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKDIFGKN_02485	220668.lp_2121	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKDIFGKN_02486	220668.lp_2119	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKDIFGKN_02487	220668.lp_2118	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKDIFGKN_02488	220668.lp_2116	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKDIFGKN_02489	220668.lp_2115	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKDIFGKN_02490	220668.lp_2114	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HKDIFGKN_02491	220668.lp_2113	1.86e-94	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKDIFGKN_02492	220668.lp_2112	5.12e-31	-	-	-	-	-	-	-	-
HKDIFGKN_02493	220668.lp_2111	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDIFGKN_02494	220668.lp_2110	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_02495	220668.lp_2109	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKDIFGKN_02496	220668.lp_2108	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HKDIFGKN_02497	220668.lp_2107	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKDIFGKN_02498	220668.lp_2106	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKDIFGKN_02499	220668.lp_2105	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HKDIFGKN_02500	220668.lp_2104	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HKDIFGKN_02501	220668.lp_2103	1.43e-223	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HKDIFGKN_02502	220668.lp_2102	1.94e-244	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HKDIFGKN_02503	220668.lp_2101	2.71e-297	-	-	-	-	-	-	-	-
HKDIFGKN_02504	220668.lp_2100	3.4e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HKDIFGKN_02505	220668.lp_2099	0.0	cps4J	-	-	S	-	-	-	MatE
HKDIFGKN_02506	220668.lp_2098	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKDIFGKN_02507	220668.lp_2097	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HKDIFGKN_02508	220668.lp_2096	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKDIFGKN_02509	220668.lp_2095	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKDIFGKN_02510	220668.lp_2094	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKDIFGKN_02511	220668.lp_2093	6.62e-62	-	-	-	-	-	-	-	-
HKDIFGKN_02512	220668.lp_2090	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKDIFGKN_02513	220668.lp_2089	1.01e-179	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKDIFGKN_02514	220668.lp_2088	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HKDIFGKN_02515	220668.lp_2087	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HKDIFGKN_02516	220668.lp_2086	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKDIFGKN_02517	220668.lp_2085	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDIFGKN_02518	220668.lp_2084	1.36e-268	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKDIFGKN_02519	220668.lp_2083	3.66e-50	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HKDIFGKN_02520	220668.lp_2082	2.21e-178	-	-	-	Q	-	-	-	Methyltransferase
HKDIFGKN_02521	220668.lp_2081	1.75e-43	-	-	-	-	-	-	-	-
HKDIFGKN_02523	220668.lp_2078	1.61e-292	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HKDIFGKN_02524	220668.lp_2077	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDIFGKN_02525	220668.lp_2076	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKDIFGKN_02526	220668.lp_2075	5.43e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HKDIFGKN_02527	220668.lp_2074	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HKDIFGKN_02528	220668.lp_2071	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HKDIFGKN_02529	220668.lp_2069	3.81e-87	-	-	-	-	-	-	-	-
HKDIFGKN_02530	220668.lp_2068	1.38e-98	-	-	-	-	-	-	-	-
HKDIFGKN_02531	220668.lp_2067	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HKDIFGKN_02532	220668.lp_2066	7.8e-123	-	-	-	-	-	-	-	-
HKDIFGKN_02533	220668.lp_2063	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKDIFGKN_02534	1136177.KCA1_1750	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HKDIFGKN_02535	220668.lp_2061	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HKDIFGKN_02536	220668.lp_2060	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HKDIFGKN_02537	220668.lp_2059	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HKDIFGKN_02538	220668.lp_2058	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HKDIFGKN_02539	220668.lp_2057	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKDIFGKN_02540	220668.lp_2056	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HKDIFGKN_02541	220668.lp_2055	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKDIFGKN_02542	220668.lp_2054	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKDIFGKN_02543	220668.lp_2053	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKDIFGKN_02544	220668.lp_2052	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKDIFGKN_02545	220668.lp_2051	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKDIFGKN_02546	220668.lp_2050	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKDIFGKN_02547	220668.lp_2049	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKDIFGKN_02548	220668.lp_2048	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKDIFGKN_02549	220668.lp_2045	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKDIFGKN_02550	220668.lp_2044	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKDIFGKN_02551	220668.lp_2043	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKDIFGKN_02552	220668.lp_2042	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HKDIFGKN_02553	220668.lp_2041	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HKDIFGKN_02554	220668.lp_2040	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKDIFGKN_02555	1136177.KCA1_1729	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKDIFGKN_02556	220668.lp_2038	0.0	-	-	-	G	-	-	-	Major Facilitator
HKDIFGKN_02557	220668.lp_2037	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKDIFGKN_02558	220668.lp_2036	1.63e-121	-	-	-	-	-	-	-	-
HKDIFGKN_02559	220668.lp_2035	1.24e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKDIFGKN_02560	220668.lp_2034	1.47e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HKDIFGKN_02561	220668.lp_2033	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKDIFGKN_02562	220668.lp_2032	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKDIFGKN_02563	220668.lp_2031	1.53e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKDIFGKN_02564	220668.lp_2030	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HKDIFGKN_02565	220668.lp_2029	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKDIFGKN_02566	220668.lp_2028	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKDIFGKN_02567	220668.lp_2027	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKDIFGKN_02568	220668.lp_2026	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKDIFGKN_02569	220668.lp_2021	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HKDIFGKN_02570	220668.lp_2020	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKDIFGKN_02571	220668.lp_2019	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKDIFGKN_02572	220668.lp_2018	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HKDIFGKN_02573	220668.lp_2017	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKDIFGKN_02574	220668.lp_2016	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKDIFGKN_02575	220668.lp_2015	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKDIFGKN_02576	1423743.JCM14108_3128	1.43e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKDIFGKN_02579	220668.lp_1994	1e-66	-	-	-	-	-	-	-	-
HKDIFGKN_02580	220668.lp_1992	4.78e-65	-	-	-	-	-	-	-	-
HKDIFGKN_02581	220668.lp_1991	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKDIFGKN_02582	220668.lp_1990	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HKDIFGKN_02583	220668.lp_1989	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKDIFGKN_02584	220668.lp_1988	1.8e-76	-	-	-	-	-	-	-	-
HKDIFGKN_02585	220668.lp_1987	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKDIFGKN_02586	220668.lp_1986	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKDIFGKN_02587	220668.lp_1985	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HKDIFGKN_02588	220668.lp_1983	1.47e-210	-	-	-	G	-	-	-	Fructosamine kinase
HKDIFGKN_02589	220668.lp_1982	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HKDIFGKN_02590	220668.lp_1981	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKDIFGKN_02591	220668.lp_1980	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKDIFGKN_02592	220668.lp_1979	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKDIFGKN_02593	220668.lp_1978	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKDIFGKN_02594	220668.lp_1977	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKDIFGKN_02595	220668.lp_1976	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKDIFGKN_02596	220668.lp_1975	4.2e-139	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKDIFGKN_02597	220668.lp_1974	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKDIFGKN_02598	1136177.KCA1_1688	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKDIFGKN_02599	220668.lp_1972	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HKDIFGKN_02600	220668.lp_1970	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HKDIFGKN_02601	220668.lp_1969	3.14e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKDIFGKN_02602	220668.lp_1968	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HKDIFGKN_02603	220668.lp_1967	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKDIFGKN_02604	220668.lp_1966	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKDIFGKN_02605	220668.lp_1965	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKDIFGKN_02606	220668.lp_1964	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKDIFGKN_02607	220668.lp_1963	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKDIFGKN_02608	220668.lp_1962	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKDIFGKN_02609	220668.lp_1959	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKDIFGKN_02610	220668.lp_1958	2.1e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_02611	220668.lp_1957	2.13e-255	-	-	-	-	-	-	-	-
HKDIFGKN_02612	220668.lp_1956	1.85e-203	-	-	-	-	-	-	-	-
HKDIFGKN_02613	220668.lp_1955	6.05e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKDIFGKN_02614	220668.lp_1954	1.03e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_02615	1321779.HMPREF1984_00059	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKDIFGKN_02616	220668.lp_1949	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKDIFGKN_02617	220668.lp_1948	2.25e-93	-	-	-	K	-	-	-	MarR family
HKDIFGKN_02618	220668.lp_1947	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKDIFGKN_02620	220668.lp_1945	1.86e-46	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_02621	220668.lp_1945	1.18e-142	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_02622	220668.lp_1944	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKDIFGKN_02623	220668.lp_1943	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKDIFGKN_02624	220668.lp_1942	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HKDIFGKN_02625	220668.lp_1941	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKDIFGKN_02627	220668.lp_1939	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKDIFGKN_02628	220668.lp_1938	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02629	220668.lp_1937	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HKDIFGKN_02630	220668.lp_1936	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
HKDIFGKN_02631	220668.lp_1935	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
HKDIFGKN_02632	220668.lp_1934	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKDIFGKN_02633	220668.lp_1933	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HKDIFGKN_02634	220668.lp_1932	1.77e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HKDIFGKN_02635	568703.LGG_00320	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDIFGKN_02636	314315.LCA_1541	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_02637	797515.HMPREF9103_02326	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HKDIFGKN_02638	60520.HR47_11995	5.58e-274	-	-	-	S	-	-	-	membrane
HKDIFGKN_02639	60520.HR47_12000	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_02640	220668.lp_1931	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HKDIFGKN_02641	220668.lp_1930	8.09e-146	-	-	-	GM	-	-	-	epimerase
HKDIFGKN_02642	220668.lp_1929	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HKDIFGKN_02643	220668.lp_1928	7.32e-91	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HKDIFGKN_02644	220668.lp_1927	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKDIFGKN_02645	220668.lp_1926	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HKDIFGKN_02646	220668.lp_1925	1.41e-38	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKDIFGKN_02647	220668.lp_1925	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKDIFGKN_02648	220668.lp_1923	1.3e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKDIFGKN_02649	220668.lp_1922	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02650	220668.lp_1921	9.28e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HKDIFGKN_02651	220668.lp_1920	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKDIFGKN_02652	220668.lp_1919	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKDIFGKN_02653	220668.lp_1918	1.02e-230	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKDIFGKN_02654	220668.lp_1916	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKDIFGKN_02655	220668.lp_1915	1.93e-266	-	-	-	-	-	-	-	-
HKDIFGKN_02656	220668.lp_1914	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKDIFGKN_02657	220668.lp_1913	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
HKDIFGKN_02658	220668.lp_1912	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HKDIFGKN_02659	220668.lp_1911	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKDIFGKN_02660	220668.lp_1910	8.46e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKDIFGKN_02661	220668.lp_1909	5.09e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKDIFGKN_02662	220668.lp_1908	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HKDIFGKN_02663	220668.lp_1906	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKDIFGKN_02664	220668.lp_1905	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKDIFGKN_02665	220668.lp_1904	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKDIFGKN_02666	220668.lp_1903	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKDIFGKN_02668	220668.lp_1900	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKDIFGKN_02669	220668.lp_1899	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKDIFGKN_02670	220668.lp_1898	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKDIFGKN_02671	220668.lp_1897	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKDIFGKN_02672	220668.lp_1894	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HKDIFGKN_02673	220668.lp_1893	4.59e-217	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HKDIFGKN_02674	220668.lp_1892	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HKDIFGKN_02675	220668.lp_1891	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKDIFGKN_02676	220668.lp_1890	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKDIFGKN_02677	220668.lp_1889	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKDIFGKN_02678	220668.lp_1888	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKDIFGKN_02679	220668.lp_1887	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKDIFGKN_02680	220668.lp_1886	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
HKDIFGKN_02681	220668.lp_1885	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKDIFGKN_02682	220668.lp_1884	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HKDIFGKN_02683	220668.lp_1883	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKDIFGKN_02684	220668.lp_1882	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKDIFGKN_02685	220668.lp_1881	5.89e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKDIFGKN_02686	1400520.LFAB_08160	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKDIFGKN_02687	220668.lp_1877	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HKDIFGKN_02688	220668.lp_1876	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKDIFGKN_02689	220668.lp_1874	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKDIFGKN_02690	220668.lp_1873	6.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKDIFGKN_02691	220668.lp_1872	6.46e-109	-	-	-	-	-	-	-	-
HKDIFGKN_02692	220668.lp_1871	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_02693	220668.lp_1870	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKDIFGKN_02694	220668.lp_1869	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKDIFGKN_02695	220668.lp_1868	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HKDIFGKN_02696	220668.lp_1867	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKDIFGKN_02697	220668.lp_1866	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HKDIFGKN_02698	220668.lp_1865	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKDIFGKN_02699	220668.lp_1864	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HKDIFGKN_02700	220668.lp_1863	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_02701	220668.lp_1860	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HKDIFGKN_02702	220668.lp_1859	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKDIFGKN_02703	220668.lp_1858	1.73e-220	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HKDIFGKN_02704	220668.lp_1857	1.73e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKDIFGKN_02705	220668.lp_1856	5.99e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
HKDIFGKN_02707	220668.lp_1854	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKDIFGKN_02708	220668.lp_1853	8.64e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKDIFGKN_02709	220668.lp_1852	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HKDIFGKN_02710	220668.lp_1850	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKDIFGKN_02711	220668.lp_1848	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKDIFGKN_02712	220668.lp_1847	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HKDIFGKN_02713	1136177.KCA1_1594	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKDIFGKN_02714	220668.lp_1845	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKDIFGKN_02715	220668.lp_1843	3.64e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKDIFGKN_02716	220668.lp_1842	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKDIFGKN_02717	220668.lp_1840	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKDIFGKN_02718	220668.lp_1839	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKDIFGKN_02719	220668.lp_1838	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02720	220668.lp_1837	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HKDIFGKN_02721	220668.lp_1836	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HKDIFGKN_02722	220668.lp_1835	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKDIFGKN_02723	220668.lp_1834	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HKDIFGKN_02724	220668.lp_1833	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HKDIFGKN_02725	220668.lp_1825	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKDIFGKN_02726	220668.lp_1824	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HKDIFGKN_02727	220668.lp_1823	3.22e-87	-	-	-	-	-	-	-	-
HKDIFGKN_02728	220668.lp_1822	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKDIFGKN_02729	220668.lp_1821	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKDIFGKN_02730	220668.lp_1820	1.4e-122	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKDIFGKN_02731	220668.lp_1819	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKDIFGKN_02732	220668.lp_1818	8.63e-275	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKDIFGKN_02733	220668.lp_1817	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKDIFGKN_02734	220668.lp_1816	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HKDIFGKN_02735	220668.lp_1815	4.55e-288	-	-	-	-	-	-	-	-
HKDIFGKN_02736	220668.lp_1814	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HKDIFGKN_02737	220668.lp_1813	7.79e-78	-	-	-	-	-	-	-	-
HKDIFGKN_02738	220668.lp_1812	2.79e-181	-	-	-	-	-	-	-	-
HKDIFGKN_02739	220668.lp_1811	7.45e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKDIFGKN_02740	220668.lp_1809	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HKDIFGKN_02741	220668.lp_1807	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HKDIFGKN_02742	220668.lp_1806	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HKDIFGKN_02744	220668.lp_1803	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKDIFGKN_02745	220668.lp_1801	4.01e-190	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HKDIFGKN_02746	220668.lp_1800	2.37e-65	-	-	-	-	-	-	-	-
HKDIFGKN_02747	220668.lp_1799	2.29e-36	-	-	-	-	-	-	-	-
HKDIFGKN_02748	220668.lp_1798	4.81e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKDIFGKN_02749	220668.lp_1797	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HKDIFGKN_02750	220668.lp_1796	5.29e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
HKDIFGKN_02751	220668.lp_1795	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02752	220668.lp_1793	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HKDIFGKN_02753	220668.lp_1792	1.6e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKDIFGKN_02754	220668.lp_1791	5.3e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_02755	220668.lp_1790	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
HKDIFGKN_02756	220668.lp_1789	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HKDIFGKN_02757	220668.lp_1788	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HKDIFGKN_02758	220668.lp_1787	1.92e-168	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HKDIFGKN_02761	220668.lp_1786	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HKDIFGKN_02762	220668.lp_1785	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKDIFGKN_02763	220668.lp_1784	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKDIFGKN_02764	220668.lp_1783	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HKDIFGKN_02765	220668.lp_1782	7.75e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKDIFGKN_02766	220668.lp_1781	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKDIFGKN_02767	220668.lp_1780	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKDIFGKN_02768	220668.lp_1779	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HKDIFGKN_02769	220668.lp_1778	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HKDIFGKN_02770	220668.lp_1777	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HKDIFGKN_02771	220668.lp_1776	2.01e-266	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HKDIFGKN_02772	220668.lp_1774	2.13e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HKDIFGKN_02773	220668.lp_1773	2.27e-247	-	-	-	-	-	-	-	-
HKDIFGKN_02774	220668.lp_1771	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKDIFGKN_02775	220668.lp_1770	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKDIFGKN_02776	220668.lp_1768	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HKDIFGKN_02777	220668.lp_1767	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HKDIFGKN_02778	60520.HR47_12515	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDIFGKN_02779	220668.lp_1764	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HKDIFGKN_02780	220668.lp_1763	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HKDIFGKN_02781	220668.lp_1762	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
HKDIFGKN_02782	220668.lp_1760	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HKDIFGKN_02783	220668.lp_1759	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKDIFGKN_02784	220668.lp_1757	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDIFGKN_02785	220668.lp_1756	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKDIFGKN_02787	1136177.KCA1_1523	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKDIFGKN_02788	220668.lp_1753	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKDIFGKN_02789	220668.lp_1752	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKDIFGKN_02790	220668.lp_1751	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HKDIFGKN_02791	220668.lp_1750	8.03e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKDIFGKN_02792	220668.lp_1749	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKDIFGKN_02793	220668.lp_1748	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDIFGKN_02794	220668.lp_1747	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HKDIFGKN_02795	220668.lp_1746	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKDIFGKN_02796	220668.lp_1745	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_02797	220668.lp_1744	6.64e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKDIFGKN_02799	220668.lp_1741	9.32e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HKDIFGKN_02800	220668.lp_1740	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKDIFGKN_02801	220668.lp_1739	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HKDIFGKN_02802	220668.lp_1738	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HKDIFGKN_02803	220668.lp_1737	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKDIFGKN_02804	220668.lp_1735	6.01e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HKDIFGKN_02805	220668.lp_1734	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HKDIFGKN_02806	220668.lp_1733	1.03e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HKDIFGKN_02807	220668.lp_1732	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKDIFGKN_02808	220668.lp_1731	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKDIFGKN_02809	220668.lp_1730	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKDIFGKN_02810	220668.lp_1729	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKDIFGKN_02811	220668.lp_1726	1.38e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKDIFGKN_02812	220668.lp_1724	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HKDIFGKN_02813	220668.lp_1723	3.56e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKDIFGKN_02814	220668.lp_1722	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKDIFGKN_02815	220668.lp_1721	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKDIFGKN_02816	220668.lp_1718	3.23e-58	-	-	-	-	-	-	-	-
HKDIFGKN_02817	220668.lp_1717	1.25e-66	-	-	-	-	-	-	-	-
HKDIFGKN_02818	220668.lp_1716	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HKDIFGKN_02819	220668.lp_1715	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HKDIFGKN_02820	220668.lp_1713	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKDIFGKN_02821	1136177.KCA1_1460	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HKDIFGKN_02822	220668.lp_1711	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDIFGKN_02823	220668.lp_1709	1.06e-53	-	-	-	-	-	-	-	-
HKDIFGKN_02824	220668.lp_1708	4e-40	-	-	-	S	-	-	-	CsbD-like
HKDIFGKN_02825	220668.lp_1706	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HKDIFGKN_02826	220668.lp_1705	5.79e-21	-	-	-	-	-	-	-	-
HKDIFGKN_02827	220668.lp_1704	1.51e-48	-	-	-	-	-	-	-	-
HKDIFGKN_02828	220668.lp_1703	3.6e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKDIFGKN_02829	220668.lp_1702	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKDIFGKN_02830	220668.lp_1701	1.51e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKDIFGKN_02831	220668.lp_1700	2.47e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HKDIFGKN_02832	220668.lp_1699	2.05e-55	-	-	-	-	-	-	-	-
HKDIFGKN_02833	220668.lp_1698	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKDIFGKN_02834	220668.lp_1697	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HKDIFGKN_02835	1400520.LFAB_17370	1.05e-41	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDIFGKN_02836	220668.lp_1696	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKDIFGKN_02837	220668.lp_1695	2.02e-39	-	-	-	-	-	-	-	-
HKDIFGKN_02838	220668.lp_1694	1.48e-71	-	-	-	-	-	-	-	-
HKDIFGKN_02839	220668.lp_1690	2.29e-193	-	-	-	O	-	-	-	Band 7 protein
HKDIFGKN_02840	220668.lp_1689	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_02841	220668.lp_1688	6.05e-121	-	-	-	K	-	-	-	transcriptional regulator
HKDIFGKN_02842	220668.lp_1687	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKDIFGKN_02843	220668.lp_1686	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HKDIFGKN_02844	220668.lp_1685	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HKDIFGKN_02845	220668.lp_1684	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKDIFGKN_02846	220668.lp_1682	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HKDIFGKN_02847	220668.lp_1681	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HKDIFGKN_02848	220668.lp_1680	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HKDIFGKN_02849	220668.lp_1679	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKDIFGKN_02850	220668.lp_1678	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HKDIFGKN_02851	220668.lp_1677	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HKDIFGKN_02852	220668.lp_1676	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKDIFGKN_02853	220668.lp_1675	7.64e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKDIFGKN_02854	220668.lp_1674	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKDIFGKN_02855	220668.lp_1673	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HKDIFGKN_02856	220668.lp_1672	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKDIFGKN_02857	220668.lp_1671	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKDIFGKN_02858	220668.lp_1670	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKDIFGKN_02859	220668.lp_1669	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02860	220668.lp_1668	1.96e-185	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKDIFGKN_02862	220668.lp_1667	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HKDIFGKN_02863	220668.lp_1665	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKDIFGKN_02864	220668.lp_1664	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HKDIFGKN_02865	220668.lp_1663	2.8e-277	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HKDIFGKN_02866	220668.lp_1662	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKDIFGKN_02867	220668.lp_1660	2.04e-226	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HKDIFGKN_02868	220668.lp_1659	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HKDIFGKN_02869	220668.lp_1658	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKDIFGKN_02870	220668.lp_1657	5.13e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKDIFGKN_02871	220668.lp_1656	6.4e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HKDIFGKN_02872	220668.lp_1655	1.7e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HKDIFGKN_02873	220668.lp_1654	4.06e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKDIFGKN_02874	220668.lp_1653	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HKDIFGKN_02875	220668.lp_1652	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HKDIFGKN_02877	220668.lp_1649	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKDIFGKN_02878	220668.lp_1648	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKDIFGKN_02879	220668.lp_1645	9.06e-112	-	-	-	-	-	-	-	-
HKDIFGKN_02880	220668.lp_1643	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKDIFGKN_02881	1045004.OKIT_0519	1.15e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HKDIFGKN_02882	1423780.LOT_2224	1.85e-110	-	-	-	-	-	-	-	-
HKDIFGKN_02883	1423807.BACO01000083_gene2425	9.94e-54	-	-	-	-	-	-	-	-
HKDIFGKN_02884	1423734.JCM14202_2802	1.35e-26	-	-	-	-	-	-	-	-
HKDIFGKN_02885	1291743.LOSG293_220100	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HKDIFGKN_02886	220668.45723572	2.21e-227	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKDIFGKN_02887	1423807.BACO01000056_gene1646	3.99e-34	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKDIFGKN_02888	1122149.BACN01000143_gene320	1.85e-44	-	-	-	-	-	-	-	-
HKDIFGKN_02889	1400520.LFAB_17305	1.79e-247	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKDIFGKN_02890	1423743.JCM14108_1576	1.44e-39	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HKDIFGKN_02891	1423775.BAMN01000001_gene2579	7.03e-06	-	-	-	-	-	-	-	-
HKDIFGKN_02892	1114972.AUAW01000009_gene2161	6.58e-199	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKDIFGKN_02893	278197.PEPE_0381	2.16e-256	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKDIFGKN_02894	46256.BBIK01000001_gene294	0.0	-	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
HKDIFGKN_02895	1114972.AUAW01000006_gene2510	5.59e-46	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKDIFGKN_02896	1400520.LFAB_17400	5.82e-124	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HKDIFGKN_02897	220668.lp_0866	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HKDIFGKN_02898	220668.lp_0865	1.48e-27	-	-	-	-	-	-	-	-
HKDIFGKN_02899	220668.lp_0864	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HKDIFGKN_02900	220668.lp_0863	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HKDIFGKN_02901	220668.lp_0862	6.12e-115	-	-	-	-	-	-	-	-
HKDIFGKN_02902	220668.lp_0861	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKDIFGKN_02903	220668.lp_0860	3.8e-61	-	-	-	-	-	-	-	-
HKDIFGKN_02904	220668.lp_0858	3.13e-89	-	-	-	O	-	-	-	OsmC-like protein
HKDIFGKN_02905	220668.lp_0857	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKDIFGKN_02906	220668.lp_0856	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HKDIFGKN_02907	220668.lp_0854	4.12e-228	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKDIFGKN_02908	220668.lp_0853	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKDIFGKN_02909	220668.lp_0852	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKDIFGKN_02910	220668.lp_0850	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKDIFGKN_02911	220668.lp_0849	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKDIFGKN_02912	220668.lp_0848	1.03e-286	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKDIFGKN_02913	220668.lp_0846	1.36e-27	-	-	-	-	-	-	-	-
HKDIFGKN_02914	220668.lp_0845	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HKDIFGKN_02915	220668.lp_0844	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HKDIFGKN_02916	220668.lp_0843	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKDIFGKN_02917	220668.lp_0842	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKDIFGKN_02918	220668.lp_0841	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKDIFGKN_02919	220668.lp_0840	1.31e-315	-	-	-	EGP	-	-	-	Major Facilitator
HKDIFGKN_02920	220668.lp_0838	1.71e-116	-	-	-	V	-	-	-	VanZ like family
HKDIFGKN_02921	220668.lp_0837	3.88e-46	-	-	-	-	-	-	-	-
HKDIFGKN_02922	220668.lp_0836	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HKDIFGKN_02924	220668.lp_0835	6.37e-186	-	-	-	-	-	-	-	-
HKDIFGKN_02925	220668.lp_0834	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKDIFGKN_02926	1136177.KCA1_0666	6.68e-177	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKDIFGKN_02927	220668.lp_0829	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HKDIFGKN_02928	220668.lp_0828	2.49e-95	-	-	-	-	-	-	-	-
HKDIFGKN_02929	220668.lp_0827	3.38e-70	-	-	-	-	-	-	-	-
HKDIFGKN_02930	220668.lp_0826	3.43e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKDIFGKN_02931	220668.lp_0825	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDIFGKN_02932	220668.lp_0824	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKDIFGKN_02933	220668.lp_0823	5.44e-159	-	-	-	T	-	-	-	EAL domain
HKDIFGKN_02934	220668.lp_0822	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKDIFGKN_02935	220668.lp_0820	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKDIFGKN_02936	220668.lp_0819	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HKDIFGKN_02937	220668.lp_0818	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKDIFGKN_02938	220668.lp_0817	8.06e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HKDIFGKN_02939	220668.lp_0816	1.25e-118	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKDIFGKN_02940	220668.lp_0815	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKDIFGKN_02941	220668.lp_0814	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKDIFGKN_02942	220668.lp_0813	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HKDIFGKN_02943	220668.lp_0812	1.46e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKDIFGKN_02944	220668.lp_0811	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKDIFGKN_02945	220668.lp_0810	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKDIFGKN_02946	220668.lp_0809	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HKDIFGKN_02947	220668.lp_0807	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HKDIFGKN_02948	220668.lp_0806	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKDIFGKN_02949	220668.lp_0805	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKDIFGKN_02950	220668.lp_0804	7.98e-137	-	-	-	-	-	-	-	-
HKDIFGKN_02951	60520.HR47_07585	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDIFGKN_02952	220668.lp_0802	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDIFGKN_02953	220668.lp_0800	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKDIFGKN_02954	220668.lp_0799	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKDIFGKN_02955	220668.lp_0797	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKDIFGKN_02956	220668.lp_0796	4.47e-178	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HKDIFGKN_02957	220668.lp_0795	3.55e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKDIFGKN_02958	220668.lp_0794	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKDIFGKN_02959	220668.lp_0793	2.83e-168	-	-	-	-	-	-	-	-
HKDIFGKN_02960	220668.lp_0792	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKDIFGKN_02961	220668.lp_0791	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKDIFGKN_02962	220668.lp_0790	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKDIFGKN_02963	220668.lp_0789	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKDIFGKN_02964	220668.lp_0788	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HKDIFGKN_02965	220668.lp_0787	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HKDIFGKN_02967	220668.lp_0786	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKDIFGKN_02968	220668.lp_0785	4.25e-223	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKDIFGKN_02969	220668.lp_0783	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKDIFGKN_02970	220668.lp_0781	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKDIFGKN_02971	220668.lp_0780	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKDIFGKN_02972	220668.lp_0779	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKDIFGKN_02973	220668.lp_0778	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKDIFGKN_02974	220668.lp_0776	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HKDIFGKN_02975	220668.lp_0775	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKDIFGKN_02976	220668.lp_0774	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKDIFGKN_02977	220668.lp_0773	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKDIFGKN_02978	220668.lp_0772	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKDIFGKN_02979	220668.lp_0771	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HKDIFGKN_02980	220668.lp_0770	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HKDIFGKN_02981	220668.lp_0769	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HKDIFGKN_02982	220668.lp_0766	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKDIFGKN_02983	220668.lp_0765	1.19e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKDIFGKN_02984	220668.lp_0764	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKDIFGKN_02985	220668.lp_0763	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKDIFGKN_02986	220668.lp_0762	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKDIFGKN_02987	220668.lp_0761	1.23e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKDIFGKN_02988	220668.lp_0760	0.0	nox	-	-	C	-	-	-	NADH oxidase
HKDIFGKN_02989	220668.lp_0758	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKDIFGKN_02990	220668.lp_0757	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKDIFGKN_02991	220668.lp_0756	1.2e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKDIFGKN_02992	220668.lp_0755	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKDIFGKN_02993	220668.lp_0754	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKDIFGKN_02994	220668.lp_0753	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HKDIFGKN_02995	220668.lp_0752	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HKDIFGKN_02996	220668.lp_0751	6.31e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKDIFGKN_02997	220668.lp_0750	2.69e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKDIFGKN_02998	220668.lp_0749	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKDIFGKN_02999	220668.lp_0748	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HKDIFGKN_03000	220668.lp_0747	9.05e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKDIFGKN_03001	220668.lp_0746	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKDIFGKN_03002	220668.lp_0744	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKDIFGKN_03003	220668.lp_0743	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKDIFGKN_03004	220668.lp_0742	6.09e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKDIFGKN_03005	220668.lp_0741	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKDIFGKN_03006	220668.lp_0739	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKDIFGKN_03007	1136177.KCA1_0576	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKDIFGKN_03008	220668.lp_0736	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HKDIFGKN_03009	220668.lp_0735	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HKDIFGKN_03010	220668.lp_0734	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HKDIFGKN_03011	220668.lp_0733	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKDIFGKN_03012	220668.lp_0730	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HKDIFGKN_03013	220668.lp_0729	0.0	ydaO	-	-	E	-	-	-	amino acid
HKDIFGKN_03014	220668.lp_0728	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKDIFGKN_03015	220668.lp_0727	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKDIFGKN_03016	220668.lp_0726	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDIFGKN_03017	220668.lp_0725	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKDIFGKN_03018	220668.lp_0723	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HKDIFGKN_03019	220668.lp_0721	1.48e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKDIFGKN_03020	220668.lp_0720	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKDIFGKN_03021	220668.lp_0718	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HKDIFGKN_03022	220668.lp_0717	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HKDIFGKN_03023	220668.lp_0715	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HKDIFGKN_03024	220668.lp_0714	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKDIFGKN_03025	60520.HR47_07220	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HKDIFGKN_03026	220668.lp_0712	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDIFGKN_03027	220668.lp_0711	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HKDIFGKN_03028	220668.lp_0710	9.25e-271	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HKDIFGKN_03029	220668.lp_0709	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKDIFGKN_03030	220668.lp_0708	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HKDIFGKN_03031	220668.lp_0707	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKDIFGKN_03032	220668.lp_0706	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKDIFGKN_03033	220668.lp_0705	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKDIFGKN_03034	220668.lp_0704	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HKDIFGKN_03035	220668.lp_0703	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKDIFGKN_03036	220668.lp_0701	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HKDIFGKN_03037	1136177.KCA1_0545	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKDIFGKN_03038	220668.lp_0699	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKDIFGKN_03039	220668.lp_0698	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKDIFGKN_03040	220668.lp_0696	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKDIFGKN_03041	220668.lp_0695	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HKDIFGKN_03042	220668.lp_0694	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HKDIFGKN_03043	220668.lp_0693	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKDIFGKN_03044	220668.lp_0692	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKDIFGKN_03045	220668.lp_0691	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKDIFGKN_03046	220668.lp_0690	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKDIFGKN_03047	220668.lp_0689	4.82e-86	-	-	-	L	-	-	-	nuclease
HKDIFGKN_03048	220668.lp_0688	8.86e-212	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKDIFGKN_03049	1136177.KCA1_0530	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKDIFGKN_03050	220668.lp_0621	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKDIFGKN_03051	220668.lp_0620	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKDIFGKN_03052	220668.lp_0619	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKDIFGKN_03053	60520.HR47_02280	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDIFGKN_03054	220668.lp_0617	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKDIFGKN_03055	220668.lp_0616	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKDIFGKN_03056	1136177.KCA1_0523	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKDIFGKN_03057	220668.lp_0614	1.77e-54	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HKDIFGKN_03058	220668.lp_0613	1.75e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HKDIFGKN_03059	220668.lp_0612	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKDIFGKN_03060	220668.lp_0611	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKDIFGKN_03061	220668.lp_0610	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKDIFGKN_03062	220668.lp_0609	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKDIFGKN_03063	220668.lp_0607	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HKDIFGKN_03064	220668.lp_0606	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKDIFGKN_03065	220668.lp_0604	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HKDIFGKN_03066	220668.lp_0603	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HKDIFGKN_03067	220668.lp_0602	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKDIFGKN_03068	220668.lp_0601	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKDIFGKN_03069	220668.lp_0600	1.86e-146	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKDIFGKN_03070	220668.lp_0597	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKDIFGKN_03071	220668.lp_0595	1.22e-226	-	-	-	EG	-	-	-	EamA-like transporter family
HKDIFGKN_03072	220668.lp_0594	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HKDIFGKN_03073	220668.lp_0593	1.32e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKDIFGKN_03074	220668.lp_0592	3.37e-175	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HKDIFGKN_03075	220668.lp_0591	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKDIFGKN_03076	220668.lp_0590	1.98e-314	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HKDIFGKN_03077	220668.lp_0589	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HKDIFGKN_03078	220668.lp_0588	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKDIFGKN_03079	220668.lp_0587	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKDIFGKN_03080	220668.lp_0586	4.16e-93	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKDIFGKN_03081	220668.lp_0585	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HKDIFGKN_03082	1136177.KCA1_0496	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HKDIFGKN_03083	1136177.KCA1_0495	4.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKDIFGKN_03084	1136177.KCA1_0494	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HKDIFGKN_03085	1136177.KCA1_0493	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKDIFGKN_03086	220668.lp_0574	1.39e-153	-	-	-	G	-	-	-	Peptidase_C39 like family
HKDIFGKN_03088	220668.lp_0572	1.9e-198	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKDIFGKN_03089	220668.lp_0571	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKDIFGKN_03090	220668.lp_0570	3.76e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HKDIFGKN_03091	220668.lp_0569	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HKDIFGKN_03092	220668.lp_0568	2.57e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HKDIFGKN_03093	220668.lp_0567	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKDIFGKN_03094	220668.lp_0566	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKDIFGKN_03095	220668.lp_0565	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKDIFGKN_03096	220668.lp_0564	5.44e-175	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKDIFGKN_03097	220668.lp_0563	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKDIFGKN_03098	220668.lp_0562	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKDIFGKN_03099	220668.lp_0561	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKDIFGKN_03100	220668.lp_0559	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKDIFGKN_03101	220668.lp_0558	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HKDIFGKN_03102	220668.lp_0557	3.1e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HKDIFGKN_03103	220668.lp_0556	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HKDIFGKN_03104	220668.lp_0555	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HKDIFGKN_03108	220668.lp_0552	5.01e-193	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKDIFGKN_03109	220668.lp_0551	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HKDIFGKN_03111	862970.SAIN_1721	1.47e-55	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKDIFGKN_03113	545243.BAEV01000056_gene203	7.8e-40	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKDIFGKN_03115	334390.LAF_1769	3.25e-75	-	-	-	L	-	-	-	4.5 Transposon and IS